The Apoe(−/−) mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction

por Lo Sasso, Giuseppe, Schlage, Walter K., Boué, Stéphanie, Veljkovic, Emilija, Peitsch, Manuel C., Hoeng, Julia
Publicado 2016

Comparison of monoamine oxidase inhibition by cigarettes and modified risk tobacco products

por van der Toorn, Marco, Koshibu, Kyoko, Schlage, Walter K., Majeed, Shoaib, Pospisil, Pavel, Hoeng, Julia, Peitsch, Manuel C.
Publicado 2019

Iota-carrageenan extracted from red algae is a potent inhibitor of SARS‐CoV-2 infection in reconstituted human airway epithelia

por Bovard, David, van der Toorn, Marco, Schlage, Walter K., Constant, Samuel, Renggli, Kasper, Peitsch, Manuel C., Hoeng, Julia
Publicado 2021

Systems Approaches Evaluating the Perturbation of Xenobiotic Metabolism in Response to Cigarette Smoke Exposure in Nasal and Bronchial Tissues

por Iskandar, Anita R., Martin, Florian, Talikka, Marja, Schlage, Walter K., Kostadinova, Radina, Mathis, Carole, Hoeng, Julia, Peitsch, Manuel C.
Publicado 2013

Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-Diseased Lung Cells Using a Dedicated Dataset

por Belcastro, Vincenzo, Poussin, Carine, Gebel, Stephan, Mathis, Carole, Schlage, Walter K., Lichtner, Rosemarie B., Quadt-Humme, Sibille, Wagner, Sandra, Hoeng, Julia, Peitsch, Manuel C.
Publicado 2013

Fractionation and Extraction Optimization of Potentially Valuable Compounds and Their Profiling in Six Varieties of Two Nicotiana Species

por Laszlo, Csaba, Kaminski, Kacper, Guan, Haifeng, Fatarova, Maria, Wei, Jianbing, Bergounioux, Alexandre, Schlage, Walter K., Schorderet-Weber, Sandra, Guy, Philippe A., Ivanov, Nikolai V., Lamottke, Kai, Hoeng, Julia
Publicado 2022

In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures

por Schlage, Walter K., Iskandar, Anita R., Kostadinova, Radina, Xiang, Yang, Sewer, Alain, Majeed, Shoaib, Kuehn, Diana, Frentzel, Stefan, Talikka, Marja, Geertz, Marcel, Mathis, Carole, Ivanov, Nikolai, Hoeng, Julia, Peitsch, Manuel C.
Publicado 2014

Construction of a Computable Network Model for DNA Damage, Autophagy, Cell Death, and Senescence

por Gebel, Stephan, Lichtner, Rosemarie B., Frushour, Brian, Schlage, Walter K., Hoang, Vy, Talikka, Marja, Hengstermann, Arnd, Mathis, Carole, Veljkovic, Emilija, Peck, Michael, Peitsch, Manuel C., Deehan, Renee, Hoeng, Julia, Westra, Jurjen W.
Publicado 2013

Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems

por Boué, Stéphanie, Talikka, Marja, Westra, Jurjen Willem, Hayes, William, Di Fabio, Anselmo, Park, Jennifer, Schlage, Walter K., Sewer, Alain, Fields, Brett, Ansari, Sam, Martin, Florian, Veljkovic, Emilija, Kenney, Renee, Peitsch, Manuel C., Hoeng, Julia
Publicado 2015

A Modular Cell-Type Focused Inflammatory Process Network Model for Non-Diseased Pulmonary Tissue

por Westra, Jurjen W., Schlage, Walter K., Hengstermann, Arnd, Gebel, Stephan, Mathis, Carole, Thomson, Ty, Wong, Ben, Hoang, Vy, Veljkovic, Emilija, Peck, Michael, Lichtner, Rosemarie B., Weisensee, Dirk, Talikka, Marja, Deehan, Renee, Hoeng, Julia, Peitsch, Manuel C.
Publicado 2013

Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach

por Iskandar, Anita R., Martinez, Yannick, Martin, Florian, Schlage, Walter K., Leroy, Patrice, Sewer, Alain, Torres, Laura Ortega, Majeed, Shoaib, Merg, Celine, Trivedi, Keyur, Guedj, Emmanuel, Frentzel, Stefan, Mathis, Carole, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia
Publicado 2017

On Crowd-verification of Biological Networks

por Ansari, Sam, Binder, Jean, Boue, Stephanie, Di Fabio, Anselmo, Hayes, William, Hoeng, Julia, Iskandar, Anita, Kleiman, Robin, Norel, Raquel, O’Neel, Bruce, Peitsch, Manuel C., Poussin, Carine, Pratt, Dexter, Rhrissorrakrai, Kahn, Schlage, Walter K., Stolovitzky, Gustavo, Talikka, Marja
Publicado 2013

A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue

por Schlage, Walter K, Westra, Jurjen W, Gebel, Stephan, Catlett, Natalie L, Mathis, Carole, Frushour, Brian P, Hengstermann, Arnd, Van Hooser, Aaron, Poussin, Carine, Wong, Ben, Lietz, Michael, Park, Jennifer, Drubin, David, Veljkovic, Emilija, Peitsch, Manuel C, Hoeng, Julia, Deehan, Renee
Publicado 2011

Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse stra...

por Cabanski, Maciej, Fields, Brett, Boue, Stephanie, Boukharov, Natalia, DeLeon, Hector, Dror, Natalie, Geertz, Marcel, Guedj, Emmanuel, Iskandar, Anita, Kogel, Ulrike, Merg, Celine, Peck, Michael J., Poussin, Carine, Schlage, Walter K., Talikka, Marja, Ivanov, Nikolai V., Hoeng, Julia, Peitsch, Manuel C.
Publicado 2015

Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case

por Schlage, Walter K., Titz, Bjoern, Iskandar, Anita, Poussin, Carine, Van der Toorn, Marco, Wong, Ee Tsin, Pratte, Pascal, Maeder, Serge, Schaller, Jean-Pierre, Pospisil, Pavel, Boue, Stephanie, Vuillaume, Grégory, Leroy, Patrice, Martin, Florian, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia
Publicado 2020

Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE(−/−...

por Kogel, Ulrike, Wong, Ee Tsin, Szostak, Justyna, Tan, Wei Teck, Lucci, Francesco, Leroy, Patrice, Titz, Bjoern, Xiang, Yang, Low, Tiffany, Wong, Sin Kei, Guedj, Emmanuel, Ivanov, Nikolai V., Schlage, Walter K., Peitsch, Manuel C., Kuczaj, Arkadiusz, Vanscheeuwijck, Patrick, Hoeng, Julia
Publicado 2021

A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability

por De León, Héctor, Boué, Stéphanie, Schlage, Walter K, Boukharov, Natalia, Westra, Jurjen W, Gebel, Stephan, VanHooser, Aaron, Talikka, Marja, Fields, R Brett, Veljkovic, Emilija, Peck, Michael J, Mathis, Carole, Hoang, Vy, Poussin, Carine, Deehan, Renee, Stolle, Katrin, Hoeng, Julia, Peitsch, Manuel C
Publicado 2014

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe(−/−) Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Produ...

por Phillips, Blaine, Veljkovic, Emilija, Boué, Stéphanie, Schlage, Walter K., Vuillaume, Gregory, Martin, Florian, Titz, Bjoern, Leroy, Patrice, Buettner, Ansgar, Elamin, Ashraf, Oviedo, Alberto, Cabanski, Maciej, De León, Héctor, Guedj, Emmanuel, Schneider, Thomas, Talikka, Marja, Ivanov, Nikolai V., Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia
Publicado 2016

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe(−/−) Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Produ...

por Phillips, Blaine, Veljkovic, Emilija, Boué, Stéphanie, Schlage, Walter K., Vuillaume, Gregory, Martin, Florian, Titz, Bjoern, Leroy, Patrice, Buettner, Ansgar, Elamin, Ashraf, Oviedo, Alberto, Cabanski, Maciej, De León, Héctor, Guedj, Emmanuel, Schneider, Thomas, Talikka, Marja, Ivanov, Nikolai V., Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia
Publicado 2016

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe(−/−) Mice—An Integrative Systems Toxicology...

por Titz, Bjoern, Boué, Stéphanie, Phillips, Blaine, Talikka, Marja, Vihervaara, Terhi, Schneider, Thomas, Nury, Catherine, Elamin, Ashraf, Guedj, Emmanuel, Peck, Michael J., Schlage, Walter K., Cabanski, Maciej, Leroy, Patrice, Vuillaume, Gregory, Martin, Florian, Ivanov, Nikolai V., Veljkovic, Emilija, Ekroos, Kim, Laaksonen, Reijo, Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia
Publicado 2016