Synthesis and structure–activity relationships of pyrazole-based inhibitors of meprin α and β

por Tan, Kathrin, Jäger, Christian, Geissler, Stefanie, Schlenzig, Dagmar, Buchholz, Mirko, Ramsbeck, Daniel
Publicado 2023

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold‐Hopping Approach

por Tan, Kathrin, Jäger, Christian, Körschgen, Hagen, Geissler, Stefanie, Schlenzig, Dagmar, Buchholz, Mirko, Stöcker, Walter, Ramsbeck, Daniel
Publicado 2020

Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor

por Linnert, Miriam, Fritz, Claudia, Jäger, Christian, Schlenzig, Dagmar, Ramsbeck, Daniel, Kleinschmidt, Martin, Wermann, Michael, Demuth, Hans-Ulrich, Parthier, Christoph, Schilling, Stephan
Publicado 2021

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor

por Bayly-Jones, Charles, Lupton, Christopher J., Fritz, Claudia, Venugopal, Hariprasad, Ramsbeck, Daniel, Wermann, Michael, Jäger, Christian, de Marco, Alex, Schilling, Stephan, Schlenzig, Dagmar, Whisstock, James C.
Publicado 2022