Targeting RNA G‐quadruplexes as new treatment strategy for C9orf72 ALS/FTD

por Schludi, Martin H, Edbauer, Dieter
Publicado 2017

Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD

por Khosravi, Bahram, Hartmann, Hannelore, May, Stephanie, Möhl, Christoph, Ederle, Helena, Michaelsen, Meike, Schludi, Martin H., Dormann, Dorothee, Edbauer, Dieter
Publicado 2017

Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing

por Schludi, Martin H., May, Stephanie, Grässer, Friedrich A., Rentzsch, Kristin, Kremmer, Elisabeth, Küpper, Clemens, Klopstock, Thomas, Arzberger, Thomas, Edbauer, Dieter
Publicado 2015

Erratum to: Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing

por Schludi, Martin H., May, Stephanie, Grässer, Friedrich A., Rentzsch, Kristin, Kremmer, Elisabeth, Küpper, Clemens, Klopstock, Thomas, Arzberger, Thomas, Edbauer, Dieter
Publicado 2015

Loss of TMEM106B potentiates lysosomal and FTLD‐like pathology in progranulin‐deficient mice

por Werner, Georg, Damme, Markus, Schludi, Martin, Gnörich, Johannes, Wind, Karin, Fellerer, Katrin, Wefers, Benedikt, Wurst, Wolfgang, Edbauer, Dieter, Brendel, Matthias, Haass, Christian, Capell, Anja
Publicado 2020

A novel CHCHD10 mutation implicates a Mia40‐dependent mitochondrial import deficit in ALS

por Lehmer, Carina, Schludi, Martin H, Ransom, Linnea, Greiling, Johanna, Junghänel, Michaela, Exner, Nicole, Riemenschneider, Henrick, van der Zee, Julie, Van Broeckhoven, Christine, Weydt, Patrick, Heneka, Michael T, Edbauer, Dieter
Publicado 2018

C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration

por May, Stephanie, Hornburg, Daniel, Schludi, Martin H., Arzberger, Thomas, Rentzsch, Kristin, Schwenk, Benjamin M., Grässer, Friedrich A., Mori, Kohji, Kremmer, Elisabeth, Banzhaf-Strathmann, Julia, Mann, Matthias, Meissner, Felix, Edbauer, Dieter
Publicado 2014

Antibodies inhibit transmission and aggregation of C9orf72 poly‐GA dipeptide repeat proteins

por Zhou, Qihui, Lehmer, Carina, Michaelsen, Meike, Mori, Kohji, Alterauge, Dominik, Baumjohann, Dirk, Schludi, Martin H, Greiling, Johanna, Farny, Daniel, Flatley, Andrew, Feederle, Regina, May, Stephanie, Schreiber, Franziska, Arzberger, Thomas, Kuhm, Christoph, Klopstock, Thomas, Hermann, Andreas, Haass, Christian, Edbauer, Dieter
Publicado 2017

TDP‐43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons

por Schwenk, Benjamin M, Hartmann, Hannelore, Serdaroglu, Alperen, Schludi, Martin H, Hornburg, Daniel, Meissner, Felix, Orozco, Denise, Colombo, Alessio, Tahirovic, Sabina, Michaelsen, Meike, Schreiber, Franziska, Haupt, Simone, Peitz, Michael, Brüstle, Oliver, Küpper, Clemens, Klopstock, Thomas, Otto, Markus, Ludolph, Albert C, Arzberger, Thomas, Kuhn, Peer‐Hendrik, Edbauer, Dieter
Publicado 2016

Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss

por Schludi, Martin H., Becker, Lore, Garrett, Lillian, Gendron, Tania F., Zhou, Qihui, Schreiber, Franziska, Popper, Bastian, Dimou, Leda, Strom, Tim M., Winkelmann, Juliane, von Thaden, Anne, Rentzsch, Kristin, May, Stephanie, Michaelsen, Meike, Schwenk, Benjamin M., Tan, Jing, Schoser, Benedikt, Dieterich, Marianne, Petrucelli, Leonard, Hölter, Sabine M., Wurst, Wolfgang, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabe, Klopstock, Thomas, Arzberger, Thomas, Edbauer, Dieter
Publicado 2017

Poly‐GP in cerebrospinal fluid links C9orf72‐associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD

por Lehmer, Carina, Oeckl, Patrick, Weishaupt, Jochen H, Volk, Alexander E, Diehl‐Schmid, Janine, Schroeter, Matthias L, Lauer, Martin, Kornhuber, Johannes, Levin, Johannes, Fassbender, Klaus, Landwehrmeyer, Bernhard, Schludi, Martin H, Arzberger, Thomas, Kremmer, Elisabeth, Flatley, Andrew, Feederle, Regina, Steinacker, Petra, Weydt, Patrick, Ludolph, Albert C, Edbauer, Dieter, Otto, Markus, Danek, Adrian, Feneberg, Emily, Anderl‐Straub, Sarah, von Arnim, Christine, Jahn, Holger, Schneider, Anja, Maler, Manuel, Polyakova, Maryna, Riedl, Lina, Wiltfang, Jens, Ziegler, Georg
Publicado 2017