Balkan endemic nephropathy: an update on its aetiology

por Stiborová, Marie, Arlt, Volker M., Schmeiser, Heinz H.
Publicado 2016

DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer

por Stiborová, Marie, Arlt, Volker M., Schmeiser, Heinz H.
Publicado 2017

Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers

por Stiborová, Marie, Hudeček, Jiří, Frei, Eva, Schmeiser, Heinz H.
Publicado 2008

Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches

por Stiborová, Marie, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Martínek, Václav
Publicado 2014

Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-m...

por Stiborová, Marie, Naiman, Karel, Martínková, Markéta, Martínek, Václav, Svobodová, Martina, Schmeiser, Heinz H., Frei, Eva
Publicado 2009

A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches

por Stiborová, Marie, Bárta, František, Levová, Kateřina, Hodek, Petr, Schmeiser, Heinz H., Arlt, Volker M., Martínek, Václav
Publicado 2015

Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1

por Milichovský, Jan, Bárta, František, Schmeiser, Heinz H., Arlt, Volker M., Frei, Eva, Stiborová, Marie, Martínek, Václav
Publicado 2016

Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches

por Martínek, Václav, Bárta, František, Hodek, Petr, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Stiborová, Marie
Publicado 2017

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

por Cerna, Tereza, Hrabeta, Jan, Eckschlager, Tomas, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Stiborová, Marie
Publicado 2018

Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study

por Stiborová, Marie, Martínek, Václav, Semanská, Marcela, Hodek, Petr, Dračínský, Martin, Cvačka, Josef, Schmeiser, Heinz H., Frei, Eva
Publicado 2009

Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone

por Mizerovská, Jana, Dračínská, Helena, Arlt, Volker M., Hudeček, Jiří, Hodek, Petr, Schmeiser, Heinz H, Frei, Eva, Stiborová, Marie
Publicado 2008

NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1

por Stiborová, Marie, Indra, Radek, Moserová, Michaela, Šulc, Miroslav, Hodek, Petr, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M.
Publicado 2016

The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers

por Šulc, Miroslav, Indra, Radek, Moserová, Michaela, Schmeiser, Heinz H., Frei, Eva, Arlt, Volker M., Stiborová, Marie, White, P.
Publicado 2016

The impact of p53 function on the metabolic activation of the carcinogenic air pollutant 3-nitrobenzanthrone and its metabolites 3-aminobenzanthrone and N-hydroxy-3-aminobenzanthro...

por Wohak, Laura E, Baranski, Ann-Christin, Krais, Annette M, Schmeiser, Heinz H, Phillips, David H, Arlt, Volker M
Publicado 2018

NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene

por Stiborová, Marie, Indra, Radek, Moserová, Michaela, Frei, Eva, Schmeiser, Heinz H., Kopka, Klaus, Philips, David H., Arlt, Volker M.
Publicado 2016

Correction to NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a...

por Stiborová, Marie, Indra, Radek, Moserová, Michaela, Frei, Eva, Schmeiser, Heinz H., Kopka, Klaus, Phillips, David H., Arlt, Volker M.
Publicado 2016

Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats

por Stiborová, Marie, Dračínská, Helena, Bořek-Dohalská, Lucie, Klusoňová, Zuzana, Holecová, Jana, Martínková, Markéta, Schmeiser, Heinz H., Arlt, Volker M.
Publicado 2018

TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

por Kucab, Jill E., van Steeg, Harry, Luijten, Mirjam, Schmeiser, Heinz H., White, Paul A., Phillips, David H., Arlt, Volker M.
Publicado 2015

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

por Kucab, Jill E., Zwart, Edwin P., van Steeg, Harry, Luijten, Mirjam, Schmeiser, Heinz H., Phillips, David H., Arlt, Volker M.
Publicado 2016

Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats

por Bárta, František, Dedíková, Alena, Bebová, Michaela, Dušková, Šárka, Mráz, Jaroslav, Schmeiser, Heinz H., Arlt, Volker M., Hodek, Petr, Stiborová, Marie
Publicado 2021