Protein engineering strategies for rational immunogen design

por Caradonna, Timothy M., Schmidt, Aaron G.
Publicado 2021

Peptide Inhibitors of Dengue-Virus Entry Target a Late-Stage Fusion Intermediate

por Schmidt, Aaron G., Yang, Priscilla L., Harrison, Stephen C.
Publicado 2010

Mechanisms that promote the evolution of cross-reactive antibodies upon vaccination with designed influenza immunogens

por Yang, Leerang, Caradonna, Timothy M., Schmidt, Aaron G., Chakraborty, Arup K.
Publicado 2023

Small-Molecule Inhibitors of Dengue-Virus Entry

por Schmidt, Aaron G., Lee, Kyungae, Yang, Priscilla L., Harrison, Stephen C.
Publicado 2012

Correction: Small-Molecule Inhibitors of Dengue-Virus Entry

por Schmidt, Aaron G., Lee, Kyungae, Yang, Priscilla L., Harrison, Stephen C.
Publicado 2019

Sequential conformational rearrangements in flavivirus membrane fusion

por Chao, Luke H, Klein, Daryl E, Schmidt, Aaron G, Peña, Jennifer M, Harrison, Stephen C
Publicado 2014

Correction: Sequential conformational rearrangements in flavivirus membrane fusion

por Chao, Luke H, Klein, Daryl E, Schmidt, Aaron G, Peña, Jennifer M, Harrison, Stephen C
Publicado 2015

Affinity maturation in a human humoral response to influenza hemagglutinin

por McCarthy, Kevin R., Raymond, Donald D., Do, Khoi T., Schmidt, Aaron G., Harrison, Stephen C.
Publicado 2019

Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody

por Phillips, Angela M, Maurer, Daniel P, Brooks, Caelan, Dupic, Thomas, Schmidt, Aaron G, Desai, Michael M
Publicado 2023

Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity

por McCarthy, Kevin R., Schmidt, Aaron G., Kirmaier, Andrea, Wyand, Allison L., Newman, Ruchi M., Johnson, Welkin E.
Publicado 2013

Humoral responses to the SARS-CoV-2 spike and receptor binding domain in context of pre-existing immunity confer broad sarbecovirus neutralization

por Hauser, Blake M., Sangesland, Maya, Lam, Evan C., Feldman, Jared, Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Publicado 2022

Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies

por Bajic, Goran, van der Poel, Cees E., Kuraoka, Masayuki, Schmidt, Aaron G., Carroll, Michael C., Kelsoe, Garnett, Harrison, Stephen C.
Publicado 2019

Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

por Raymond, Donald D., Bajic, Goran, Ferdman, Jack, Suphaphiphat, Pirada, Settembre, Ethan C., Moody, M. Anthony, Schmidt, Aaron G., Harrison, Stephen C.
Publicado 2018

Coronavirus-Specific Antibody Cross Reactivity in Rhesus Macaques following SARS-CoV-2 Vaccination and Infection

por Jacob-Dolan, Catherine, Feldman, Jared, McMahan, Katherine, Yu, Jingyou, Zahn, Roland, Wegmann, Frank, Schuitemaker, Hanneke, Schmidt, Aaron G., Barouch, Dan H.
Publicado 2021

Altering the Immunogenicity of Hemagglutinin Immunogens by Hyperglycosylation and Disulfide Stabilization

por Thornlow, Dana N., Macintyre, Andrew N., Oguin, Thomas H., Karlsson, Amelia B., Stover, Erica L., Lynch, Heather E., Sempowski, Gregory D., Schmidt, Aaron G.
Publicado 2021

Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein

por Joshi, Vinita R., Newman, Ruchi M., Pack, Melissa L., Power, Karen A., Munro, James B., Okawa, Ken, Madani, Navid, Sodroski, Joseph G., Schmidt, Aaron G., Allen, Todd M.
Publicado 2020

Heterologous sarbecovirus receptor binding domains as scaffolds for SARS-CoV-2 receptor binding motif presentation

por Hauser, Blake M., Sangesland, Maya, Lam, Evan C., Denis, Kerri J. St., Sheehan, Maegan L., Vu, Mya L., Cheng, Agnes H., Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Publicado 2023

Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage

por Xu, Huafeng, Schmidt, Aaron G, O'Donnell, Timothy, Therkelsen, Matthew D, Kepler, Thomas B, Moody, M Anthony, Haynes, Barton F, Liao, Hua-Xin, Harrison, Stephen C, Shaw, David E
Publicado 2015

Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells

por Amraei, Razie, Xia, Chaoshuang, Olejnik, Judith, White, Mitchell R., Napoleon, Marc A., Lotfollahzadeh, Saran, Hauser, Blake M., Schmidt, Aaron G., Chitalia, Vipul, Mühlberger, Elke, Costello, Catherine E., Rahimi, Nader
Publicado 2022

A bivalent ChAd nasal vaccine protects against SARS-CoV-2 BQ.1.1 and XBB.1.5 infection and disease in mice and hamsters

por Ying, Baoling, Darling, Tamarand L., Desai, Pritesh, Liang, Chieh-Yu, Dmitriev, Igor P., Soudani, Nadia, Bricker, Traci, Kashentseva, Elena A., Harastani, Houda, Schmidt, Aaron G., Curiel, David T., Boon, Adrianus C.M., Diamond, Michael S.
Publicado 2023