2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP(+)-Dependent Isocitrate Dehydrogenase Mutations

por Jin, Genglin, Reitman, Zachary J., Spasojevic, Ivan, Batinic-Haberle, Ines, Yang, Jian, Schmidt-Kittler, Oleg, Bigner, Darell D., Yan, Hai
Publicado 2011

High-resolution array comparative genomic hybridization of single micrometastatic tumor cells

por Fuhrmann, Christine, Schmidt-Kittler, Oleg, Stoecklein, Nikolas H., Petat-Dutter, Karina, Vay, Christian, Bockler, Kerstin, Reinhardt, Richard, Ragg, Thomas, Klein, Christoph A.
Publicado 2008

Thiazolidinedione-Based PI3Kα Inhibitors: An Analysis of Biochemical and Virtual Screening Methods

por Pinson, Jo-Anne, Schmidt-Kittler, Oleg, Zhu, Jiuxiang, Jennings, Ian G, Kinzler, Kenneth W, Vogelstein, Bert, Chalmers, David K, Thompson, Philip E
Publicado 2011

PI3Kα Inhibitors That Inhibit Metastasis

por Schmidt-Kittler, Oleg, Zhu, Jiuxiang, Yang, Jian, Liu, Guosheng, Hendricks, William, Lengauer, Christoph, Gabelli, Sandra B., Kinzler, Kenneth W., Vogelstein, Bert, Huso, David L., Zhou, Shibin
Publicado 2010

Structural basis of nSH2 regulation and lipid binding in PI3Kα

por Miller, Michelle S., Schmidt-Kittler, Oleg, Bolduc, David M., Brower, Evan T., Chaves-Moreira, Daniele, Allaire, Marc, Kinzler, Kenneth W., Jennings, Ian G., Thompson, Philip E., Cole, Philip A., Amzel, L. Mario, Vogelstein, Bert, Gabelli, Sandra B.
Publicado 2014

Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma

por Yoo, Changhoon, Kang, Jihoon, Kim, Deokhoon, Kim, Kyu-Pyo, Ryoo, Baek-Yeol, Hong, Seung-Mo, Hwang, Jung Jin, Jeong, Seong-Yun, Hwang, Shin, Kim, Ki-Hun, Lee, Young-Joo, Hoeflich, Klaus P., Schmidt-Kittler, Oleg, Miller, Stephen, Choi, Eun Kyung
Publicado 2017

Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial

por DeAngelo, Daniel J., Radia, Deepti H., George, Tracy I., Robinson, William A., Quiery, Albert T., Drummond, Mark W., Bose, Prithviraj, Hexner, Elizabeth O., Winton, Elliott F., Horny, Hans-Peter, Tugnait, Meera, Schmidt-Kittler, Oleg, Evans, Erica K., Lin, Hui-Min, Mar, Brenton G., Verstovsek, Srdan, Deininger, Michael W., Gotlib, Jason
Publicado 2021

RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations

por Subbiah, Vivek, Sahai, Vaibhav, Maglic, Dejan, Bruderek, Kamil, Touré, B. Barry, Zhao, Songping, Valverde, Roberto, O'Hearn, Patrick J., Moustakas, Demetri T., Schönherr, Heike, Gerami-Moayed, Nastaran, Taylor, Alexander M., Hudson, Brandi M., Houde, Damian J., Pal, Debjani, Foster, Lindsey, Gunaydin, Hakan, Ayaz, Pelin, Sharon, Dina A., Goyal, Lipika, Schram, Alison M., Kamath, Suneel, Sherwin, Cori Ann, Schmidt-Kittler, Oleg, Jen, Kai Yu, Ricard, Fabien, Wolf, Beni B., Shaw, David E., Bergstrom, Donald A., Watters, James, Casaletto, Jessica B.
Publicado 2023