Con: are we ready to translate Alzheimer’s disease-modifying therapies to people with down syndrome?

por Head, Elizabeth, Schmitt, Frederick A
Publicado 2014

Metabolic and Vascular Imaging Biomarkers in Down Syndrome Provide Unique Insights Into Brain Aging and Alzheimer Disease Pathogenesis

por Head, Elizabeth, Powell, David K., Schmitt, Frederick A.
Publicado 2018

A practical algorithm for managing Alzheimer's disease: what, when, and why?

por Cummings, Jeffrey L, Isaacson, Richard S, Schmitt, Frederick A, Velting, Drew M
Publicado 2015

Longitudinal assessment of dementia measures in Down syndrome

por Koehl, Lisa, Harp, Jordan, Van Pelt, Kathryn L., Head, Elizabeth, Schmitt, Frederick A.
Publicado 2020

Evaluating trajectories of episodic memory in normal cognition and mild cognitive impairment: Results from ADNI

por Ding, Xiuhua, Charnigo, Richard J., Schmitt, Frederick A., Kryscio, Richard J., Abner, Erin L.
Publicado 2019

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

por Webster, Scott J., Bachstetter, Adam D., Nelson, Peter T., Schmitt, Frederick A., Van Eldik, Linda J.
Publicado 2014

Analyzing the impact of 23 mg/day donepezil on language dysfunction in moderate to severe Alzheimer's disease

por Ferris, Steven H, Schmitt, Frederick A, Saxton, Judith, Richardson, Sharon, Mackell, Joan, Sun, Yijun, Xu, Yikang
Publicado 2011

Feasibility of dual‐task gait to estimate Alzheimer's related cognitive decline in Down syndrome

por Van Pelt, Kathryn L., Koehl, Lisa, Caban‐Holt, Allison, Anderson‐Mooney, Amelia, Head, Elizabeth, Schmitt, Frederick A.
Publicado 2020

Cerebrovascular pathology in Down syndrome and Alzheimer disease

por Head, Elizabeth, Phelan, Michael J., Doran, Eric, Kim, Ronald C., Poon, Wayne W., Schmitt, Frederick A., Lott, Ira T.
Publicado 2017

Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

por Martini, Alessandra C., Helman, Alex M., McCarty, Katie L., Lott, Ira T., Doran, Eric, Schmitt, Frederick A., Head, Elizabeth
Publicado 2020

Dopaminergic Modulation of Medial Prefrontal Cortex Deactivation in Parkinson Depression

por Andersen, Anders H., Smith, Charles D., Slevin, John T., Kryscio, Richard J., Martin, Catherine A., Schmitt, Frederick A., Blonder, Lee X.
Publicado 2015

A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging

por Li, Juan, Broster, Lucas S., Jicha, Gregory A., Munro, Nancy B., Schmitt, Frederick A., Abner, Erin, Kryscio, Richard, Smith, Charles D., Jiang, Yang
Publicado 2017

Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome

por Harp, Jordan P., Koehl, Lisa M., Pelt, Kathryn L. Van, Hom, Christy L., Doran, Eric, Head, Elizabeth, Lott, Ira T., Schmitt, Frederick A.
Publicado 2021

Practice effects in a longitudinal, multi-center Alzheimer’s disease prevention clinical trial

por Abner, Erin L, Dennis, Brandon C, Mathews, Melissa J, Mendiondo, Marta S, Caban-Holt, Allison, Kryscio, Richard J, Schmitt, Frederick A, Crowley, John J
Publicado 2012

Sugihara causality analysis of scalp EEG for detection of early Alzheimer's disease

por McBride, Joseph C., Zhao, Xiaopeng, Munro, Nancy B., Jicha, Gregory A., Schmitt, Frederick A., Kryscio, Richard J., Smith, Charles D., Jiang, Yang
Publicado 2014

Hierarchical Clustering Analyses of Plasma Proteins in Subjects With Cardiovascular Risk Factors Identify Informative Subsets Based on Differential Levels of Angiogenic and Inflamm...

por Winder, Zachary, Sudduth, Tiffany L., Fardo, David, Cheng, Qiang, Goldstein, Larry B., Nelson, Peter T., Schmitt, Frederick A., Jicha, Gregory A., Wilcock, Donna M.
Publicado 2020

Memory-Related Frontal Brainwaves Predict Transition to Mild Cognitive Impairment in Healthy Older Individuals Five Years Before Diagnosis

por Jiang, Yang, Li, Juan, Schmitt, Frederick A., Jicha, Gregory A., Munro, Nancy B., Zhao, Xiaopeng, Smith, Charles D., Kryscio, Richard J., Abner, Erin L.
Publicado 2021

Peripheral (deep) but not periventricular MRI white matter hyperintensities are increased in clinical vascular dementia compared to Alzheimer's disease

por Smith, Charles D., Johnson, Eleanor S., Van Eldik, Linda J., Jicha, Gregory A., Schmitt, Frederick A., Nelson, Peter T., Kryscio, Richard J., Murphy, Ronan R., Wellnitz, Clinton V.
Publicado 2016

Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults

por Jiang, Yang, Kuan Lin, Ming, Jicha, Gregory A., Ding, Xiuhua, McIlwrath, Sabrina L., Fardo, David W., Broster, Lucas S., Schmitt, Frederick A., Kryscio, Richard, Lipsky, Robert H.
Publicado 2017

Brain structure changes over time in normal and mildly impaired aged persons

por Smith, Charles D, Van Eldik, Linda J, Jicha, Gregory A, Schmitt, Frederick A, Nelson, Peter T, Abner, Erin L, Kryscio, Richard J, Murphy, Ronan R, Andersen, Anders H
Publicado 2020