ETMR-03. THE ROLE OF FOXR2 IN PEDIATRIC BRAIN CANCER

por Schmitt-Hoffner, Felix, van Rijn, Sjoerd, Hübner, Jens-Martin, Lambo, Sander, Mauermann, Monika, Mack, Norman, Schwalm, Benjamin, Pfister, Stefan, Kool, Marcel
Publicado 2020

ETMR-11. Transcriptional changes upon knockdown of alteredBCOR/BCORL1 transcripts in preclinical models of CNS embryonal tumors with BCOR-related alterations

por Piontek, Martin, Kirchhofer, Dominik, Gabler, Lisa, Lötsch-Gojo, Daniela, Pirker, Christine, Schmitt-Hoffner, Felix, Jaunecker, Carola N, Kool, Marcel, Berger, Walter, Gojo, Johannes
Publicado 2022

FOXR2 Stabilizes MYCN Protein and Identifies Non–MYCN-Amplified Neuroblastoma Patients With Unfavorable Outcome

por Schmitt-Hoffner, Felix, van Rijn, Sjoerd, Toprak, Umut H., Mauermann, Monika, Rosemann, Felix, Heit-Mondrzyk, Anke, Hübner, Jens-Martin, Camgöz, Aylin, Hartlieb, Sabine, Pfister, Stefan M., Henrich, Kai-Oliver, Westermann, Frank, Kool, Marcel
Publicado 2021

Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma

por Krausert, Sonja, Brabetz, Sebastian, Mack, Norman L, Schmitt-Hoffner, Felix, Schwalm, Benjamin, Peterziel, Heike, Mangang, Aileen, Holland-Letz, Tim, Sieber, Laura, Korshunov, Andrey, Oehme, Ina, Jäger, Natalie, Witt, Olaf, Pfister, Stefan M, Kool, Marcel
Publicado 2022

Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation

por Korshunov, Andrey, Okonechnikov, Konstantin, Schmitt-Hoffner, Felix, Ryzhova, Marina, Sahm, Felix, Stichel, Damian, Schrimpf, Daniel, Reuss, David E., Sievers, Philipp, Suwala, Abigail Kora, Kumirova, Ella, Zheludkova, Olga, Golanov, Andrey, Jones, David T. W., Pfister, Stefan M., Kool, Marcel, von Deimling, Andreas
Publicado 2021

ETMR-12. Novel cell models of CNS tumors with BCOR fusion or internal tandem duplication suggest FGFR and PDGFR as promising therapy targets

por Kirchhofer, Dominik, Lötsch-Gojo, Daniela, Gabler, Lisa, Jaunecker, Carola N, Piontek, Martin, Mayr, Lisa, Englinger, Bernhard, Pirker, Christine, Mohr, Thomas, Lämmerer, Anna, Schmitt-Hoffner, Felix, Boidol, Bernd, Kubiceck, Stefan, Peyrl, Andreas, Azizi, Amadeo A, Dorfer, Christian, Haberler, Christine, Kool, Marcel, Berger, Walter, Gojo, Johannes
Publicado 2022

RARE-15. Astroblastoma, MN1 altered comprises two molecularly and clinically distinct subgroups defined by the fusion partners BEND2 and CXXC5

por Schmitt-Hoffner, Felix, Gojo, Johannes, Mauermann, Monika, von Hoff, Katja, Sill, Martin, Stichel, Damian, Capper, David, Tauziede-Espariat, Arnault, Varlet, Pascale, Aldape, Kenneth, Abdullaev, Zied, Donson, Andrew M, Schüller, Ulrich, Snuderl, Matija, Brandner, Sebastian, Łastowska, Maria, Trubicka, Joanna, Miele, Evelina, van der Lugt, Jasper, Bunt, Jens, Kramm, Christof, Zapotocky, Michal, Sahm, Felix, Korshunov, Andrey, Jäger, Natalie, Pfister, Stefan M, Kool, Marcel
Publicado 2022

ETMR-06. Molecular and clinical characteristics of CNS tumors withBCOR(L1) fusion/internal tandem duplication

por Gojo, Johannes, Schmitt-Hoffner, Felix, Mauermann, Monika, von Hoff, Katja, Sill, Martin, Korshunov, Andrey, Stichel, Damian, Capper, David, Tauziede-Espariat, Arnault, Varlet, Pascale, Aldape, Kenneth, Abdullaev, Zied, Donson, Andrew, Pahnke, Jens, Schüller, Ulrich, Tran, Ivy, Galbraith, Kristyn, Snuderl, Matija, Alexandrescu, Sanda, Brandner, Sebastian, Łastowska, Maria, Miele, Evelina, Lugt, Jasper v, Meijer, Lisethe, Bunt, Jens, Kramm, Christof, Hansford, Jordan R, Krskova, Lenka, Zapotocky, Michal, Nobusawa, Sumihito, Solomon, David, Haberler, Christine, Jones, Barbara, Sturm, Dominik, Sahm, Felix, Jäger, Natalie, Pfister, Stefan M, Kool, Marcel
Publicado 2022