Minimizing leukemia escape: implementing a dual anti-CD20- and CD19-scFv-based chimeric antigen receptor (CAR)

por Schneider, Dina, Xiong, Ying, Roy, Andre, Kaiser, Andrew, Dropulic, Boro, Orentas, Rimas
Publicado 2015

A tandem CD19/CD20 CAR lentiviral vector drives on-target and off-target antigen modulation in leukemia cell lines

por Schneider, Dina, Xiong, Ying, Wu, Darong, Nӧlle, Volker, Schmitz, Sarah, Haso, Waleed, Kaiser, Andrew, Dropulic, Boro, Orentas, Rimas J.
Publicado 2017

A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia

por Schneider, Dina, Xiong, Ying, Hu, Peirong, Wu, Darong, Chen, Weizao, Ying, Tianlei, Zhu, Zhongyu, Dimitrov, Dimiter S., Dropulic, Boro, Orentas, Rimas J.
Publicado 2018

Armored BCMA CAR T Cells Eliminate Multiple Myeloma and Are Resistant to the Suppressive Effects of TGF-β

por Alabanza, Leah M., Xiong, Ying, Vu, Bang, Webster, Brian, Wu, Darong, Hu, Peirong, Zhu, Zhongyu, Dropulic, Boro, Dash, Pradyot, Schneider, Dina
Publicado 2022

P1082: RESULTS FROM A PHASE 1/2 STUDY OF TANDEM, BISPECIFIC ANTI-CD20/ANTI-CD19 (LV20.19) CAR T-CELLS FOR MANTLE CELL LYMPHOMA

por Shah, Nirav N, Fenske, Timothy, Johnson, Bryon, Szabo, Aniko, Devata, Sumana, Longo, Walter, Kearl, Tyce, Zamora, Anthony, Hari, Parameswaran, Schneider, Dina, Hamadani, Mehdi
Publicado 2023

A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

por Bari, Rafijul, Granzin, Markus, Tsang, Kam Sze, Roy, Andre, Krueger, Winfried, Orentas, Rimas, Schneider, Dina, Pfeifer, Rita, Moeker, Nina, Verhoeyen, Els, Dropulic, Boro, Leung, Wing
Publicado 2019

Corrigendum: A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

por Bari, Rafijul, Granzin, Markus, Tsang, Kam Sze, Roy, Andre, Krueger, Winfried, Orentas, Rimas, Schneider, Dina, Pfeifer, Rita, Moeker, Nina, Verhoeyen, Els, Dropulic, Boro, Leung, Wing
Publicado 2019

MDA5 and TLR3 Initiate Pro-Inflammatory Signaling Pathways Leading to Rhinovirus-Induced Airways Inflammation and Hyperresponsiveness

por Wang, Qiong, Miller, David J., Bowman, Emily R., Nagarkar, Deepti R., Schneider, Dina, Zhao, Ying, Linn, Marisa J., Goldsmith, Adam M., Bentley, J. Kelley, Sajjan, Umadevi S., Hershenson, Marc B.
Publicado 2011

Transgenic mice with ectopic expression of constitutively active TLR4 in adipose tissues do not show impaired insulin sensitivity

por Ono‐Moore, Kikumi D., Zhao, Ling, Huang, Shurong, Kim, Jeonga, Rutkowsky, Jennifer M., Snodgrass, Ryan G., Schneider, Dina A., Quon, Michael J., Graham, James L., Havel, Peter J., Hwang, Daniel H.
Publicado 2017

Primary CD33-targeting CAR-NK cells for the treatment of acute myeloid leukemia

por Albinger, Nawid, Pfeifer, Rita, Nitsche, Marcus, Mertlitz, Sarah, Campe, Julia, Stein, Katja, Kreyenberg, Hermann, Schubert, Ralf, Quadflieg, Melissa, Schneider, Dina, Kühn, Michael W. M., Penack, Olaf, Zhang, Congcong, Möker, Nina, Ullrich, Evelyn
Publicado 2022

Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia

por Liu, Chao, Gates, Keith P., Fang, Longhou, Amar, Marcelo J., Schneider, Dina A., Geng, Honglian, Huang, Wei, Kim, Jungsu, Pattison, Jennifer, Zhang, Jian, Witztum, Joseph L., Remaley, Alan T., Dong, P. Duc, Miller, Yury I.
Publicado 2015

Titratable Pharmacological Regulation of CAR T Cells Using Zinc Finger-Based Transcription Factors

por Kotter, Bettina, Engert, Fabian, Krueger, Winfried, Roy, Andre, Rawashdeh, Wael Al, Cordes, Nicole, Drees, Britta, Webster, Brian, Werchau, Niels, Lock, Dominik, Dapa, Sandra, Schneider, Dina, Ludwig, Stephan, Rossig, Claudia, Assenmacher, Mario, Mittelstaet, Joerg, Kaiser, Andrew D.
Publicado 2021

Patient-reported outcomes and neurotoxicity markers in patients treated with bispecific LV20.19 CAR T cell therapy

por Knight, Jennifer M., Szabo, Aniko, Arapi, Igli, Wu, Ruizhe, Emmrich, Amanda, Hackett, Edward, Sauber, Garrett, Yim, Sharon, Johnson, Bryon, Hari, Parameswaran, Schneider, Dina, Dropulic, Boro, Cusatis, Rachel N., Cole, Steve W., Hillard, Cecilia J., Shah, Nirav N.
Publicado 2022

Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma

por Jackson, Zachary, Roe, Anne, Sharma, Ashish Arunkumar, Lopes, Filipa Blasco Tavares Pereira, Talla, Aarthi, Kleinsorge-Block, Sarah, Zamborsky, Kayla, Schiavone, Jennifer, Manjappa, Shivaprasad, Schauner, Robert, Lee, Grace, Liu, Ruifu, Caimi, Paolo F., Xiong, Ying, Krueger, Winfried, Worden, Andrew, Kadan, Mike, Schneider, Dina, Orentas, Rimas, Dropulic, Boro, Sekaly, Rafick-Pierre, de Lima, Marcos, Wald, David N., Reese, Jane S.
Publicado 2020

Multiple site place-of-care manufactured anti-CD19 CAR-T cells induce high remission rates in B-cell malignancy patients

por Maschan, Michael, Caimi, Paolo F., Reese-Koc, Jane, Sanchez, Gabriela Pacheco, Sharma, Ashish A., Molostova, Olga, Shelikhova, Larisa, Pershin, Dmitriy, Stepanov, Alexey, Muzalevskii, Yakov, Suzart, Vinicius G., Otegbeye, Folashade, Wald, David, Xiong, Ying, Wu, Darong, Knight, Adam, Oparaocha, Ibe, Ferencz, Beatrix, Roy, Andre, Worden, Andrew, Kruger, Winfried, Kadan, Michael, Schneider, Dina, Orentas, Rimas, Sekaly, Rafick-Pierre, de Lima, Marcos, Dropulić, Boro
Publicado 2021

Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma

por Tian, Meijie, Wei, Jun S., Shivaprasad, Nityashree, Highfill, Steven L., Gryder, Berkley E., Milewski, David, Brown, G. Tom, Moses, Larry, Song, Hannah, Wu, Jerry T., Azorsa, Peter, Kumar, Jeetendra, Schneider, Dina, Chou, Hsien-Chao, Song, Young K., Rahmy, Abdelrahman, Masih, Katherine E., Kim, Yong Yean, Belyea, Brian, Linardic, Corinne M., Dropulic, Boro, Sullivan, Peter M., Sorensen, Poul H., Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L., Orentas, Rimas J., Cheuk, Adam T., Khan, Javed
Publicado 2023