Therapeutic Potential for Targeting Autophagy in ER+ Breast Cancer

por Finnegan, Ryan M., Elshazly, Ahmed M., Schoenlein, Patricia V., Gewirtz, David A.
Publicado 2022

Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells

por Liu, Feiyan, Li, Xia, Lu, Chunwan, Bai, Aiping, Bielawski, Jacek, Bielawska, Alicja, Marshall, Brendan, Schoenlein, Patricia V., Lebedyeva, Iryna O., Liu, Kebin
Publicado 2016

Disruption of Immune Homeostasis in Human Dendritic Cells via Regulation of Autophagy and Apoptosis by Porphyromonas gingivalis

por Meghil, Mohamed M., Tawfik, Omnia K., Elashiry, Mahmoud, Rajendran, Mythilypriya, Arce, Roger M., Fulton, David J., Schoenlein, Patricia V., Cutler, Christopher W.
Publicado 2019

BRD4 Inhibition as a Strategy to Prolong the Response to Standard of Care in Estrogen Receptor-Positive Breast Cancer

por Elshazly, Ahmed M., Sinanian, Melanie M., Neely, Victoria, Chakraborty, Eesha, Alshehri, Muruj A., McGrath, Michael K., Harada, Hisashi, Schoenlein, Patricia V., Gewirtz, David A.
Publicado 2023

Porphyromonas gingivalis Evasion of Autophagy and Intracellular Killing by Human Myeloid Dendritic Cells Involves DC-SIGN-TLR2 Crosstalk

por El-Awady, Ahmed R., Miles, Brodie, Scisci, Elizabeth, Kurago, Zoya B., Palani, Chithra D., Arce, Roger M., Waller, Jennifer L., Genco, Caroline A., Slocum, Connie, Manning, Matthew, Schoenlein, Patricia V., Cutler, Christopher W.
Publicado 2015

Rapamycin up-regulation of autophagy reduces infarct size and improves outcomes in both permanent MCAL, and embolic MCAO, murine models of stroke

por Buckley, Kathleen M, Hess, Daniel L, Sazonova, Irina Y, Periyasamy-Thandavan, Sudharsan, Barrett, John R, Kirks, Russell, Grace, Harrison, Kondrikova, Galina, Johnson, Maribeth H, Hess, David C, Schoenlein, Patricia V, Hoda, Md Nasrul, Hill, William D
Publicado 2014

Upregulation of the EGFR/MEK1/MAPK1/2 signaling axis as a mechanism of resistance to antiestrogen-induced BimEL dependent apoptosis in ER(+) breast cancer cells

por Hagan, Mackenzie L., Mander, Suchreet, Joseph, Carol, Mcgrath, Michael, Barrett, Amanda, Lewis, Allison, Hill, William D., Browning, Darren, Mcgee-Lawrence, Meghan E., Cai, Haifeng, Liu, Kebin, Barrett, John T., Gewirtz, David A., Thangaraju, Muthusamy, Schoenlein, Patricia V.
Publicado 2022