Exosomal Transport of Hepatocyte‐Derived Drug‐Modified Proteins to the Immune System

por Ogese, Monday O., Jenkins, Rosalind E., Adair, Kareena, Tailor, Arun, Meng, Xiaoli, Faulkner, Lee, Enyindah, Bright O., Schofield, Amy, Diaz‐Nieto, Rafael, Ressel, Lorenzo, Eagle, Gina L., Kitteringham, Neil R., Goldring, Chris E., Park, B. Kevin, Naisbitt, Dean J., Betts, Catherine
Publicado 2019

Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury

por Copple, Ian M., den Hollander, Wouter, Callegaro, Giulia, Mutter, Fiona E., Maggs, James L., Schofield, Amy L., Rainbow, Lucille, Fang, Yongxiang, Sutherland, Jeffrey J., Ellis, Ewa C., Ingelman-Sundberg, Magnus, Fenwick, Stephen W., Goldring, Christopher E., van de Water, Bob, Stevens, James L., Park, B. Kevin
Publicado 2018

Systems analysis of miRNA biomarkers to inform drug safety

por Schofield, Amy L., Brown, Joseph P., Brown, Jack, Wilczynska, Ania, Bell, Catherine, Glaab, Warren E., Hackl, Matthias, Howell, Lawrence, Lee, Stephen, Dear, James W., Remes, Mika, Reeves, Paul, Zhang, Eunice, Allmer, Jens, Norris, Alan, Falciani, Francesco, Takeshita, Louise Y., Seyed Forootan, Shiva, Sutton, Robert, Park, B. Kevin, Goldring, Chris
Publicado 2021

Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury comp...

por Oppelt, Angela, Kaschek, Daniel, Huppelschoten, Suzanna, Sison-Young, Rowena, Zhang, Fang, Buck-Wiese, Marie, Herrmann, Franziska, Malkusch, Sebastian, Krüger, Carmen L., Meub, Mara, Merkt, Benjamin, Zimmermann, Lea, Schofield, Amy, Jones, Robert P., Malik, Hassan, Schilling, Marcel, Heilemann, Mike, van de Water, Bob, Goldring, Christopher E., Park, B. Kevin, Timmer, Jens, Klingmüller, Ursula
Publicado 2018

A MicroRNA Next-Generation-Sequencing Discovery Assay (miND) for Genome-Scale Analysis and Absolute Quantitation of Circulating MicroRNA Biomarkers

por Khamina, Kseniya, Diendorfer, Andreas B., Skalicky, Susanna, Weigl, Moritz, Pultar, Marianne, Krammer, Teresa L., Fournier, Catharine Aquino, Schofield, Amy L., Otto, Carolin, Smith, Aaron Thomas, Buchtele, Nina, Schoergenhofer, Christian, Jilma, Bernd, Frank, Bernhard J. H., Hofstaetter, Jochen G., Grillari, Regina, Grillari, Johannes, Ruprecht, Klemens, Goldring, Christopher E., Rehrauer, Hubert, Glaab, Warren E., Hackl, Matthias
Publicado 2022