Emerging hepatotoxicity biomarkers and their potential to improve understanding and management of drug-induced liver injury

por Aubrecht, Jiri, Schomaker, Shelli J, Amacher, David E
Publicado 2013

The MicroRNA-based Liquid Biopsy Improves Early Assessment of Lethal Acetaminophen Poisoning: A Case Report

por Krauskopf, Julian, Gosink, Mark M., Schomaker, Shelli, Caiment, Florian, Warner, Roscoe, Johnson, Kent, Kleinjans, Jos, Aubrecht, Jiri
Publicado 2020

Glutamate dehydrogenase as a biomarker for mitotoxicity; insights from furosemide hepatotoxicity in the mouse

por Church, Rachel J., Schomaker, Shelli J., Eaddy, J. Scott, Boucher, Germaine G., Kreeger, John M., Aubrecht, Jiri, Watkins, Paul B.
Publicado 2020

Serum glutamate dehydrogenase activity enables early detection of liver injury in subjects with underlying muscle impairments

por Schomaker, Shelli, Potter, David, Warner, Roscoe, Larkindale, Jane, King, Nicholas, Porter, Amy C., Owens, Jane, Tomlinson, Lindsay, Sauer, John-Michael, Johnson, Kent, Aubrecht, Jiri
Publicado 2020

Phase I study of PF‐04895162, a Kv7 channel opener, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeost...

por Aleo, Michael D., Aubrecht, Jiri, D. Bonin, Paul, Burt, Deborah A., Colangelo, Jennifer, Luo, Lina, Schomaker, Shelli, Swiss, Rachel, Kirby, Simon, C. Rigdon, Greg, Dua, Pinky
Publicado 2019

Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human

por Krauskopf, Julian, de Kok, Theo M., Schomaker, Shelli J., Gosink, Mark, Burt, Deborah A., Chandler, Patricia, Warner, Roscoe L., Johnson, Kent J., Caiment, Florian, Kleinjans, Jos C., Aubrecht, Jiri
Publicado 2017