Platelet gene therapy induces robust immune tolerance even in a primed model via peripheral clonal deletion of antigen-specific T cells

por Li, Jing, Chen, Juan, Schroeder, Jocelyn A., Hu, Jianda, Williams, Calvin B., Shi, Qizhen
Publicado 2021

Targeting transmembrane-domain-less MOG expression to platelets prevents disease development in experimental autoimmune encephalomyelitis

por Cai, Yuanhua, Schroeder, Jocelyn A., Jing, Weiqing, Gurski, Cody, Williams, Calvin B., Wang, Shaoyuan, Dittel, Bonnie N., Shi, Qizhen
Publicado 2022

Platelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells

por Luo, Xiaofeng, Chen, Juan, Schroeder, Jocelyn A., Allen, Kenneth P., Baumgartner, Christina K., Malarkannan, Subramaniam, Hu, Jianda, Williams, Calvin B., Shi, Qizhen
Publicado 2018

A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD

por Shi, Qizhen, Fahs, Scot A., Mattson, Jeremy G., Yu, Hongyin, Perry, Crystal L., Morateck, Patricia A., Schroeder, Jocelyn A., Rapten, Jessica, Weiler, Hartmut, Montgomery, Robert R.
Publicado 2022