NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM...

por Braciak, Todd A, Wildenhain, Sarah, Roskopf, Claudia C, Schubert, Ingo A, Fey, Georg H, Jacob, Uwe, Hopfner, Karl-Peter, Oduncu, Fuat S
Publicado 2013

T cell-recruiting triplebody 19-3-19 mediates serial lysis of malignant B-lymphoid cells by a single T cell

por Roskopf, Claudia C., Schiller, Christian B., Braciak, Todd A., Kobold, Sebastian, Schubert, Ingo A., Fey, Georg H., Hopfner, Karl-Peter, Oduncu, Fuat S.
Publicado 2014

CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells

por Schiller, Christian B., Braciak, Todd A., Fenn, Nadja C., Seidel, Ursula J. E., Roskopf, Claudia C., Wildenhain, Sarah, Honegger, Annemarie, Schubert, Ingo A., Schele, Alexandra, Lämmermann, Kerstin, Fey, Georg H., Jacob, Uwe, Lang, Peter, Hopfner, Karl-Peter, Oduncu, Fuat S.
Publicado 2016

Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural kille...

por Braciak, Todd A., Roskopf, Claudia C., Wildenhain, Sarah, Fenn, Nadja C., Schiller, Christian B., Schubert, Ingo A., Jacob, Uwe, Honegger, Annemarie, Krupka, Christina, Subklewe, Marion, Spiekermann, Karsten, Hopfner, Karl-Peter, Fey, Georg H., Aigner, Michael, Krause, Stefan, Mackensen, Andreas, Oduncu, Fuat S.
Publicado 2018