The Action of Key Factors in Protein Evolution at High Temporal Resolution

por Schmitt, Armin, Schuchhardt, Johannes, Brockmann, Gudrun A.
Publicado 2009

Large-scale literature mining to assess the relation between anti-cancer drugs and cancer types

por Bauer, Chris, Herwig, Ralf, Lienhard, Matthias, Prasse, Paul, Scheffer, Tobias, Schuchhardt, Johannes
Publicado 2021

Risk of chronic kidney disease in patients with acute kidney injury following a major surgery: a US claims database analysis

por Ohlmeier, Christoph, Schuchhardt, Johannes, Bauer, Chris, Brinker, Meike, Kong, Sheldon X, Scott, Charlie, Vaitsiakhovich, Tatsiana
Publicado 2023

High-throughput and single-cell imaging of NF-κB oscillations using monoclonal cell lines

por Bartfeld, Sina, Hess, Simone, Bauer, Bianca, Machuy, Nikolaus, Ogilvie, Lesley A, Schuchhardt, Johannes, Meyer, Thomas F
Publicado 2010

BioMiner: Paving the Way for Personalized Medicine

por Bauer, Chris, Stec, Karol, Glintschert, Alexander, Gruden, Kristina, Schichor, Christian, Or-Guil, Michal, Selbig, Joachim, Schuchhardt, Johannes
Publicado 2015

Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40?

por Klafki, Hans-Wolfgang, Morgado, Barbara, Wirths, Oliver, Jahn, Olaf, Bauer, Chris, Esselmann, Hermann, Schuchhardt, Johannes, Wiltfang, Jens
Publicado 2022

A minimal model of peptide binding predicts ensemble properties of serum antibodies

por Greiff, Victor, Redestig, Henning, Lück, Juliane, Bruni, Nicole, Valai, Atijeh, Hartmann, Susanne, Rausch, Sebastian, Schuchhardt, Johannes, Or-Guil, Michal
Publicado 2012

Clinical characteristics and disease outcomes in non-diabetic chronic kidney disease: retrospective analysis of a US healthcare claims database

por Wanner, Christoph, Schuchhardt, Johannes, Bauer, Chris, Lindemann, Stefanie, Brinker, Meike, Kong, Sheldon X., Kleinjung, Frank, Horvat-Broecker, Andrea, Vaitsiakhovich, Tatsiana
Publicado 2022

PPINGUIN: Peptide Profiling Guided Identification of Proteins improves quantitation of iTRAQ ratios

por Bauer, Chris, Kleinjung, Frank, Rutishauser, Dorothea, Panse, Christian, Chadt, Alexandra, Dreja, Tanja, Al-Hasani, Hadi, Reinert, Knut, Schlapbach, Ralph, Schuchhardt, Johannes
Publicado 2012

A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s d...

por Shahpasand-Kroner, Hedieh, Klafki, Hans-W., Bauer, Chris, Schuchhardt, Johannes, Hüttenrauch, Melanie, Stazi, Martina, Bouter, Caroline, Wirths, Oliver, Vogelgsang, Jonathan, Wiltfang, Jens
Publicado 2018

Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia

por Spitzer, Philipp, Schieb, Heinke, Kamrowski-Kruck, Heike, Otto, Markus, Chiasserini, Davide, Parnetti, Lucilla, Herukka, Sanna-Kaisa, Schuchhardt, Johannes, Wiltfang, Jens, Klafki, Hans-Wolfgang
Publicado 2011

Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Dataset

por Bauer, Chris, Kleinjung, Frank, Smith, Celia J, Towers, Mark W, Tiss, Ali, Chadt, Alexandra, Dreja, Tanja, Beule, Dieter, Al-Hasani, Hadi, Reinert, Knut, Schuchhardt, Johannes, Cramer, Rainer
Publicado 2011

Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer’s Disease Dementia via Lead-Lag Analysis

por Fuentes, Manuel, Klostermann, Arne, Kleineidam, Luca, Bauer, Chris, Schuchhardt, Johannes, Maier, Wolfgang, Jessen, Frank, Frölich, Lutz, Wiltfang, Jens, Kornhuber, Johannes, Klöppel, Stefan, Schieting, Vera, Teipel, Stefan J., Wagner, Michael, Peters, Oliver
Publicado 2020

Don’t forget about tau: the effects of ApoE4 genotype on Alzheimer’s disease cerebrospinal fluid biomarkers in subjects with mild cognitive impairment—data from the Dementia Compet...

por Benson, Gloria S., Bauer, Chris, Hausner, Lucrezia, Couturier, Samuel, Lewczuk, Piotr, Peters, Oliver, Hüll, Michael, Jahn, Holger, Jessen, Frank, Pantel, Johannes, Teipel, Stefan J., Wagner, Michael, Schuchhardt, Johannes, Wiltfang, Jens, Kornhuber, Johannes, Frölich, Lutz
Publicado 2022

Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation

por Klafki, Hans-W., Vogelgsang, Jonathan, Manuilova, Ekaterina, Bauer, Chris, Jethwa, Alexander, Esselmann, Hermann, Jahn-Brodmann, Anke, Osterloh, Dirk, Lachmann, Ingolf, Breitling, Benedict, Rauter, Carolin, Hansen, Niels, Bouter, Caroline, Palme, Stefan, Schuchhardt, Johannes, Wiltfang, Jens
Publicado 2022

A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

por Kuepfer, Lars, Clayton, Olivia, Thiel, Christoph, Cordes, Henrik, Nudischer, Ramona, Blank, Lars M., Baier, Vanessa, Heymans, Stephane, Caiment, Florian, Roth, Adrian, Fluri, David A., Kelm, Jens M., Castell, José, Selevsek, Nathalie, Schlapbach, Ralph, Keun, Hector, Hynes, James, Sarkans, Ugis, Gmuender, Hans, Herwig, Ralf, Niederer, Steven, Schuchhardt, Johannes, Segall, Matthew, Kleinjans, Jos
Publicado 2017

Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer’s dementia

por Frölich, Lutz, Peters, Oliver, Lewczuk, Piotr, Gruber, Oliver, Teipel, Stefan J., Gertz, Hermann J., Jahn, Holger, Jessen, Frank, Kurz, Alexander, Luckhaus, Christian, Hüll, Michael, Pantel, Johannes, Reischies, Friedel M., Schröder, Johannes, Wagner, Michael, Rienhoff, Otto, Wolf, Stefanie, Bauer, Chris, Schuchhardt, Johannes, Heuser, Isabella, Rüther, Eckart, Henn, Fritz, Maier, Wolfgang, Wiltfang, Jens, Kornhuber, Johannes
Publicado 2017

Network integration and modelling of dynamic drug responses at multi-omics levels

por Selevsek, Nathalie, Caiment, Florian, Nudischer, Ramona, Gmuender, Hans, Agarkova, Irina, Atkinson, Francis L., Bachmann, Ivo, Baier, Vanessa, Barel, Gal, Bauer, Chris, Boerno, Stefan, Bosc, Nicolas, Clayton, Olivia, Cordes, Henrik, Deeb, Sally, Gotta, Stefano, Guye, Patrick, Hersey, Anne, Hunter, Fiona M. I., Kunz, Laura, Lewalle, Alex, Lienhard, Matthias, Merken, Jort, Minguet, Jasmine, Oliveira, Bernardo, Pluess, Carla, Sarkans, Ugis, Schrooders, Yannick, Schuchhardt, Johannes, Smit, Ines, Thiel, Christoph, Timmermann, Bernd, Verheijen, Marcha, Wittenberger, Timo, Wolski, Witold, Zerck, Alexandra, Heymans, Stephane, Kuepfer, Lars, Roth, Adrian, Schlapbach, Ralph, Niederer, Steven, Herwig, Ralf, Kleinjans, Jos
Publicado 2020