Pyrvinium Pamoate: Past, Present, and Future as an Anti-Cancer Drug

por Schultz, Christopher W., Nevler, Avinoam
Publicado 2022

Repurposing the FDA-approved anthelmintic pyrvinium pamoate for pancreatic cancer treatment: study protocol for a phase I clinical trial in early-stage pancreatic ductal adenocarci...

por Ponzini, Francesca M, Schultz, Christopher W, Leiby, Benjamin E, Cannaday, Shawnna, Yeo, T, Posey, James, Bowne, Wilbur B, Yeo, Charles, Brody, Jonathan R, Lavu, Harish, Nevler, Avinoam
Publicado 2023

Replication Stress Defines Distinct Molecular Subtypes Across Cancers

por Takahashi, Nobuyuki, Kim, Sehyun, Schultz, Christopher W., Rajapakse, Vinodh N., Zhang, Yang, Redon, Christophe E., Fu, Haiqing, Pongor, Lorinc, Kumar, Suresh, Pommier, Yves, Aladjem, Mirit I., Thomas, Anish
Publicado 2022

Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents

por Jo, Ukhyun, Senatorov, Ilya S., Zimmermann, Astrid, Saha, Liton Kumar, Murai, Yasuhisa, Kim, Se Hyun, Rajapakse, Vinodh N., Elloumi, Fathi, Takahashi, Nobuyuki, Schultz, Christopher W., Thomas, Anish, Zenke, Frank T., Pommier, Yves
Publicado 2021

Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models

por Lissa, Delphine, Takahashi, Nobuyuki, Desai, Parth, Manukyan, Irena, Schultz, Christopher W., Rajapakse, Vinodh, Velez, Moises J., Mulford, Deborah, Roper, Nitin, Nichols, Samantha, Vilimas, Rasa, Sciuto, Linda, Chen, Yuanbin, Guha, Udayan, Rajan, Arun, Atkinson, Devon, El Meskini, Rajaa, Weaver Ohler, Zoe, Thomas, Anish
Publicado 2022

Validation of American Joint Committee on Cancer 8(th) edition of TNM staging in resected distal pancreatic cancer

por Yin, Feng, Saad, Mohammed, Xie, Hao, Lin, Jingmei, Jackson, Christopher R, Ren, Bing, Lawson, Cynthia, Karamchandani, Dipti M, Bernabeu, Belen Quereda, Jiang, Wei, Dhir, Teena, Zheng, Richard, Schultz, Christopher W, Zhang, Dongwei, Thomas, Courtney L, Zhang, Xuchen, Lai, Jinping, Schild, Michael, Zhang, Xuefeng, Liu, Xiuli
Publicado 2020

Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer

por Yin, Feng, Saad, Mohammed, Lin, Jingmei, Jackson, Christopher R, Ren, Bing, Lawson, Cynthia, Karamchandani, Dipti M, Bernabeu, Belen Quereda, Jiang, Wei, Dhir, Teena, Zheng, Richard, Schultz, Christopher W, Zhang, Dongwei, Thomas, Courtney L, Zhang, Xuchen, Lai, Jinping, Schild, Michael, Zhang, Xuefeng, Xie, Hao, Liu, Xiuli
Publicado 2020

ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer

por Schultz, Christopher W, Zhang, Yang, Elmeskini, Rajaa, Zimmermann, Astrid, Fu, Haiqing, Murai, Yasuhisa, Wangsa, Darawalee, Kumar, Suresh, Takahashi, Nobuyuki, Atkinson, Devon, Saha, Liton Kumar, Lee, Chien‐Fei, Elenbaas, Brian, Desai, Parth, Sebastian, Robin, Sharma, Ajit Kumar, Abel, Melissa, Schroeder, Brett, Krishnamurthy, Manan, Kumar, Rajesh, Roper, Nitin, Aladjem, Mirit, Zenke, Frank T, Ohler, Zoe Weaver, Pommier, Yves, Thomas, Anish
Publicado 2023

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis

por Palomo-Irigoyen, Marta, Pérez-Andrés, Encarni, Iruarrizaga-Lejarreta, Marta, Barreira-Manrique, Adrián, Tamayo-Caro, Miguel, Vila-Vecilla, Laura, Moreno-Cugnon, Leire, Beitia, Nagore, Medrano, Daniela, Fernández-Ramos, David, Lozano, Juan José, Okawa, Satoshi, Lavín, José L., Martín-Martín, Natalia, Sutherland, James D., de Juan, Virginia Guitiérez, Gonzalez-Lopez, Monika, Macías-Cámara, Nuria, Mosén-Ansorena, David, Laraba, Liyam, Hanemann, C. Oliver, Ercolano, Emanuela, Parkinson, David B., Schultz, Christopher W., Araúzo-Bravo, Marcos J., Ascensión, Alex M., Gerovska, Daniela, Iribar, Haizea, Izeta, Ander, Pytel, Peter, Krastel, Philipp, Provenzani, Alessandro, Seneci, Pierfausto, Carrasco, Ruben D., Del Sol, Antonio, Martinez-Chantar, María Luz, Barrio, Rosa, Serra, Eduard, Lazaro, Conxi, Flanagan, Adrienne M., Gorospe, Myriam, Ratner, Nancy, Aransay, Ana M., Carracedo, Arkaitz, Varela-Rey, Marta, Woodhoo, Ashwin
Publicado 2020