MYC-mediated resistance to trametinib and HCQ in PDAC is overcome by CDK4/6 and lysosomal inhibition

por Silvis, Mark R., Silva, Dilru, Rohweder, Riley, Schuman, Sophia, Gudipaty, Swapna, Truong, Amanda, Yap, Jeffrey, Affolter, Kajsa, McMahon, Martin, Kinsey, Conan
Publicado 2023

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAF(V600E)-Driven Lung Tumorigenesis

por Vaishnavi, Aria, Juan, Joseph, Jacob, Maebh, Stehn, Christopher, Gardner, Eric E., Scherzer, Michael T., Schuman, Sophia, Van Veen, J. Edward, Murphy, Brandon, Hackett, Christopher S., Dupuy, Adam J., Chmura, Steven A., van der Weyden, Louise, Newberg, Justin Y., Liu, Annie, Mann, Karen, Rust, Alistair G., Weiss, William A., Kinsey, Conan G., Adams, David J., Grossmann, Allie, Mann, Michael B., McMahon, Martin
Publicado 2022

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

por Kinsey, Conan G., Camolotto, Soledad A., Boespflug, Amelie M., Gullien, Katrin P., Foth, Mona, Truong, Amanda, Schuman, Sophia S., Shea, Jill E., Seipp, Michael T., Yap, Jeffrey T., Burrell, Lance D., Lum, David H., Whisenant, Jonathan R., Gilcrease, G. Weldon, Cavalieri, Courtney C., Rehbein, Kaitrin M., Cutler, Stephanie L., Affolter, Kajsa E., Welm, Alana L., Welm, Bryan E., Scaife, Courtney L., Snyder, Eric L., McMahon, Martin
Publicado 2019