Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion

por Warita, Katsuhiko, Warita, Tomoko, Beckwitt, Colin H., Schurdak, Mark E., Vazquez, Alexei, Wells, Alan, Oltvai, Zoltán N.
Publicado 2014

Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised

por Sannino, Sara, Yates, Megan E, Schurdak, Mark E, Oesterreich, Steffi, Lee, Adrian V, Wipf, Peter, Brodsky, Jeffrey L
Publicado 2021

Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers

por Gearhart, Tricia L., Montelaro, Ronald C., Schurdak, Mark E., Pilcher, Chris D., Rinaldo, Charles R., Kodadek, Thomas, Park, Yongseok, Islam, Kazi, Yurko, Raymond, Marques, Ernesto T.A., Burke, Donald S.
Publicado 2016

Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery

por Gough, Albert H., Chen, Ning, Shun, Tong Ying, Lezon, Timothy R., Boltz, Robert C., Reese, Celeste E., Wagner, Jacob, Vernetti, Lawrence A., Grandis, Jennifer R., Lee, Adrian V., Stern, Andrew M., Schurdak, Mark E., Taylor, D. Lansing
Publicado 2014

A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection

por Chen, Fangyuan, Shi, Qingya, Pei, Fen, Vogt, Andreas, Porritt, Rebecca A, Garcia, Gustavo, Gomez, Angela C, Cheng, Mary Hongying, Schurdak, Mark E, Liu, Bing, Chan, Stephen Y, Arumugaswami, Vaithilingaraja, Stern, Andrew M, Taylor, D Lansing, Arditi, Moshe, Bahar, Ivet
Publicado 2021

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology

por Pei, Fen, Li, Hongchun, Henderson, Mark J., Titus, Steven A., Jadhav, Ajit, Simeonov, Anton, Cobanoglu, Murat Can, Mousavi, Seyed H., Shun, Tongying, McDermott, Lee, Iyer, Prema, Fioravanti, Michael, Carlisle, Diane, Friedlander, Robert M., Bahar, Ivet, Taylor, D. Lansing, Lezon, Timothy R., Stern, Andrew M., Schurdak, Mark E.
Publicado 2017