A clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease

por Eoli, Andrea, Ibing, Susanne, Schurmann, Claudia, Nadkarni, Girish N., Heyne, Henrike, Böttinger, Erwin
Publicado 2023

Implementation and evaluation of personal genetic testing as part of genomics analysis courses in German universities

por Slosarek, Tamara, Ibing, Susanne, Schormair, Barbara, Heyne, Henrike O., Böttinger, Erwin P., Andlauer, Till F. M., Schurmann, Claudia
Publicado 2023

Associations between Serum Sex Hormone Concentrations and Whole Blood Gene Expression Profiles in the General Population

por Haring, Robin, Schurmann, Claudia, Homuth, Georg, Steil, Leif, Völker, Uwe, Völzke, Henry, Keevil, Brian G., Nauck, Matthias, Wallaschofski, Henri
Publicado 2015

Blood RNA expression profiles undergo major changes during the seventh decade

por Gheorghe, Marius, Schurmann, Claudia, Peters, Marjolein J., Uitterlinden, André G., Hofman, Albert, Biffar, Reiner, Homuth, Georg, Völker, Uwe, van Meurs, Joyce BJ, Raz, Vered
Publicado 2016

Helicobacter pylori colonization and obesity – a Mendelian randomization study

por den Hollander, Wouter J., Broer, Linda, Schurmann, Claudia, Meyre, David, den Hoed, Caroline M., Mayerle, Julia, Hofman, Albert, Homuth, Georg, Uitterlinden, André G., Lerch, Markus M., Kuipers, Ernst J.
Publicado 2017

Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis

por Sendler, Matthias, Beyer, Georg, Mahajan, Ujjwal M., Kauschke, Vivien, Maertin, Sandrina, Schurmann, Claudia, Homuth, Georg, Völker, Uwe, Völzke, Henry, Halangk, Walter, Wartmann, Thomas, Weiss, Frank-Ulrich, Hegyi, Peter, Lerch, Markus M., Mayerle, Julia
Publicado 2015

Genome-wide association and targeted analysis of copy number variants with psoriatic arthritis in German patients

por Uebe, Steffen, Ehrlicher, Maria, Ekici, Arif Bülent, Behrens, Frank, Böhm, Beate, Homuth, Georg, Schurmann, Claudia, Völker, Uwe, Jünger, Michael, Nauck, Matthias, Völzke, Henry, Traupe, Heiko, Krawczak, Michael, Burkhardt, Harald, Reis, André, Hüffmeier, Ulrike
Publicado 2017

Blood cis-eQTL Analysis Fails to Identify Novel Association Signals among Sub-Threshold Candidates from Genome-Wide Association Studies in Restless Legs Syndrome

por Schulte, Eva C., Schramm, Katharina, Schurmann, Claudia, Lichtner, Peter, Herder, Christian, Roden, Michael, Gieger, Christian, Peters, Annette, Trenkwalder, Claudia, Högl, Birgit, Frauscher, Birgit, Berger, Klaus, Fietze, Ingo, Gross, Nadine, Stiasny-Kolster, Karin, Oertel, Wolfgang, Bachmann, Cornelius G., Paulus, Walter, Zimprich, Alexander, Völzke, Henry, Schminke, Ulf, Nauck, Matthias, Illig, Thomas, Meitinger, Thomas, Müller-Myhsok, Bertram, Prokisch, Holger, Winkelmann, Juliane
Publicado 2014

Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity

por Shrine, Nick, Tobin, Martin D., Schurmann, Claudia, Soler Artigas, María, Hui, Jennie, Lehtimäki, Terho, Raitakari, Olli T., Pennell, Craig E., Ang, Qi Wei, Strachan, David P., Homuth, Georg, Gläser, Sven, Felix, Stephan B., Evans, David M., Henderson, John, Granell, Raquel, Palmer, Lyle J., Huffman, Jennifer, Hayward, Caroline, Scotland, Generation, Malarstig, Anders, Musk, Bill, James, Alan L., Wain, Louise V.
Publicado 2016

Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium

por Schurmann, Claudia, Heim, Katharina, Schillert, Arne, Blankenberg, Stefan, Carstensen, Maren, Dörr, Marcus, Endlich, Karlhans, Felix, Stephan B., Gieger, Christian, Grallert, Harald, Herder, Christian, Hoffmann, Wolfgang, Homuth, Georg, Illig, Thomas, Kruppa, Jochen, Meitinger, Thomas, Müller, Christian, Nauck, Matthias, Peters, Annette, Rettig, Rainer, Roden, Michael, Strauch, Konstantin, Völker, Uwe, Völzke, Henry, Wahl, Simone, Wallaschofski, Henri, Wild, Philipp S., Zeller, Tanja, Teumer, Alexander, Prokisch, Holger, Ziegler, Andreas
Publicado 2012

Mapping the Genetic Architecture of Gene Regulation in Whole Blood

por Schramm, Katharina, Marzi, Carola, Schurmann, Claudia, Carstensen, Maren, Reinmaa, Eva, Biffar, Reiner, Eckstein, Gertrud, Gieger, Christian, Grabe, Hans-Jörgen, Homuth, Georg, Kastenmüller, Gabriele, Mägi, Reedik, Metspalu, Andres, Mihailov, Evelin, Peters, Annette, Petersmann, Astrid, Roden, Michael, Strauch, Konstantin, Suhre, Karsten, Teumer, Alexander, Völker, Uwe, Völzke, Henry, Wang-Sattler, Rui, Waldenberger, Melanie, Meitinger, Thomas, Illig, Thomas, Herder, Christian, Grallert, Harald, Prokisch, Holger
Publicado 2014

Rare Genomic Structural Variants in Complex Disease: Lessons from the Replication of Associations with Obesity

por Walters, Robin G., Coin, Lachlan J. M., Ruokonen, Aimo, de Smith, Adam J., El-Sayed Moustafa, Julia S., Jacquemont, Sebastien, Elliott, Paul, Esko, Tõnu, Hartikainen, Anna-Liisa, Laitinen, Jaana, Männik, Katrin, Martinet, Danielle, Meyre, David, Nauck, Matthias, Schurmann, Claudia, Sladek, Rob, Thorleifsson, Gudmar, Thorsteinsdóttir, Unnur, Valsesia, Armand, Waeber, Gerard, Zufferey, Flore, Balkau, Beverley, Pattou, François, Metspalu, Andres, Völzke, Henry, Vollenweider, Peter, Stefansson, Kári, Järvelin, Marjo-Riitta, Beckmann, Jacques S., Froguel, Philippe, Blakemore, Alexandra I. F.
Publicado 2013

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos

por Hodonsky, Chani J., Jain, Deepti, Schick, Ursula M., Morrison, Jean V., Brown, Lisa, McHugh, Caitlin P., Schurmann, Claudia, Chen, Diane D., Liu, Yong Mei, Auer, Paul L., Laurie, Cecilia A., Taylor, Kent D., Browning, Brian L., Li, Yun, Papanicolaou, George, Rotter, Jerome I., Kurita, Ryo, Nakamura, Yukio, Browning, Sharon R., Loos, Ruth J. F., North, Kari E., Laurie, Cathy C., Thornton, Timothy A., Pankratz, Nathan, Bauer, Daniel E., Sofer, Tamar, Reiner, Alex P.
Publicado 2017

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

por Homuth, Georg, Wahl, Simone, Müller, Christian, Schurmann, Claudia, Mäder, Ulrike, Blankenberg, Stefan, Carstensen, Maren, Dörr, Marcus, Endlich, Karlhans, Englbrecht, Christian, Felix, Stephan B., Gieger, Christian, Grallert, Harald, Herder, Christian, Illig, Thomas, Kruppa, Jochen, Marzi, Carola S., Mayerle, Julia, Meitinger, Thomas, Metspalu, Andres, Nauck, Matthias, Peters, Annette, Rathmann, Wolfgang, Reinmaa, Eva, Rettig, Rainer, Roden, Michael, Schillert, Arne, Schramm, Katharina, Steil, Leif, Strauch, Konstantin, Teumer, Alexander, Völzke, Henry, Wallaschofski, Henri, Wild, Philipp S., Ziegler, Andreas, Völker, Uwe, Prokisch, Holger, Zeller, Tanja
Publicado 2015

Genetic identification of a common collagen disease in Puerto Ricans via identity-by-descent mapping in a health system

por Belbin, Gillian Morven, Odgis, Jacqueline, Sorokin, Elena P, Yee, Muh-Ching, Kohli, Sumita, Glicksberg, Benjamin S, Gignoux, Christopher R, Wojcik, Genevieve L, Van Vleck, Tielman, Jeff, Janina M, Linderman, Michael, Schurmann, Claudia, Ruderfer, Douglas, Cai, Xiaoqiang, Merkelson, Amanda, Justice, Anne E, Young, Kristin L, Graff, Misa, North, Kari E, Peters, Ulrike, James, Regina, Hindorff, Lucia, Kornreich, Ruth, Edelmann, Lisa, Gottesman, Omri, Stahl, Eli EA, Cho, Judy H, Loos, Ruth JF, Bottinger, Erwin P, Nadkarni, Girish N, Abul-Husn, Noura S, Kenny, Eimear E
Publicado 2017

A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans

por Liu, Fan, van der Lijn, Fedde, Schurmann, Claudia, Zhu, Gu, Chakravarty, M. Mallar, Hysi, Pirro G., Wollstein, Andreas, Lao, Oscar, de Bruijne, Marleen, Ikram, M. Arfan, van der Lugt, Aad, Rivadeneira, Fernando, Uitterlinden, André G., Hofman, Albert, Niessen, Wiro J., Homuth, Georg, de Zubicaray, Greig, McMahon, Katie L., Thompson, Paul M., Daboul, Amro, Puls, Ralf, Hegenscheid, Katrin, Bevan, Liisa, Pausova, Zdenka, Medland, Sarah E., Montgomery, Grant W., Wright, Margaret J., Wicking, Carol, Boehringer, Stefan, Spector, Timothy D., Paus, Tomáš, Martin, Nicholas G., Biffar, Reiner, Kayser, Manfred
Publicado 2012

Testing the role of predicted gene knockouts in human anthropometric trait variation

por Lessard, Samuel, Manning, Alisa K., Low-Kam, Cécile, Auer, Paul L., Giri, Ayush, Graff, Mariaelisa, Schurmann, Claudia, Yaghootkar, Hanieh, Luan, Jian'an, Esko, Tonu, Karaderi, Tugce, Bottinger, Erwin P., Lu, Yingchang, Carlson, Chris, Caulfield, Mark, Dubé, Marie-Pierre, Jackson, Rebecca D., Kooperberg, Charles, McKnight, Barbara, Mongrain, Ian, Peters, Ulrike, Reiner, Alex P., Rhainds, David, Sotoodehnia, Nona, Hirschhorn, Joel N., Scott, Robert A., Munroe, Patricia B., Frayling, Timothy M., Loos, Ruth J.F., North, Kari E., Edwards, Todd L., Tardif, Jean-Claude, Lindgren, Cecilia M., Lettre, Guillaume
Publicado 2016

Burden Analysis of Rare Microdeletions Suggests a Strong Impact of Neurodevelopmental Genes in Genetic Generalised Epilepsies

por Lal, Dennis, Ruppert, Ann-Kathrin, Trucks, Holger, Schulz, Herbert, de Kovel, Carolien G., Kasteleijn-Nolst Trenité, Dorothée, Sonsma, Anja C. M., Koeleman, Bobby P., Lindhout, Dick, Weber, Yvonne G., Lerche, Holger, Kapser, Claudia, Schankin, Christoph J., Kunz, Wolfram S., Surges, Rainer, Elger, Christian E., Gaus, Verena, Schmitz, Bettina, Helbig, Ingo, Muhle, Hiltrud, Stephani, Ulrich, Klein, Karl M., Rosenow, Felix, Neubauer, Bernd A., Reinthaler, Eva M., Zimprich, Fritz, Feucht, Martha, Møller, Rikke S., Hjalgrim, Helle, De Jonghe, Peter, Suls, Arvid, Lieb, Wolfgang, Franke, Andre, Strauch, Konstantin, Gieger, Christian, Schurmann, Claudia, Schminke, Ulf, Nürnberg, Peter, Sander, Thomas
Publicado 2015

A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension

por Huan, Tianxiao, Esko, Tõnu, Peters, Marjolein J., Pilling, Luke C., Schramm, Katharina, Schurmann, Claudia, Chen, Brian H., Liu, Chunyu, Joehanes, Roby, Johnson, Andrew D., Yao, Chen, Ying, Sai-xia, Courchesne, Paul, Milani, Lili, Raghavachari, Nalini, Wang, Richard, Liu, Poching, Reinmaa, Eva, Dehghan, Abbas, Hofman, Albert, Uitterlinden, André G., Hernandez, Dena G., Bandinelli, Stefania, Singleton, Andrew, Melzer, David, Metspalu, Andres, Carstensen, Maren, Grallert, Harald, Herder, Christian, Meitinger, Thomas, Peters, Annette, Roden, Michael, Waldenberger, Melanie, Dörr, Marcus, Felix, Stephan B., Zeller, Tanja, Vasan, Ramachandran, O'Donnell, Christopher J., Munson, Peter J., Yang, Xia, Prokisch, Holger, Völker, Uwe, van Meurs, Joyce B. J., Ferrucci, Luigi, Levy, Daniel
Publicado 2015

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations

por Bonnemaijer, Pieter W. M., Iglesias, Adriana I., Nadkarni, Girish N., Sanyiwa, Anna J., Hassan, Hassan G., Cook, Colin, Simcoe, Mark, Taylor, Kent D., Schurmann, Claudia, Belbin, Gillian M., Kenny, Eimear E., Bottinger, Erwin P., van de Laar, Suzanne, Wiliams, Susan E. I., Akafo, Stephen K., Ashaye, Adeyinka O., Zangwill, Linda M., Girkin, Christopher A., Ng, Maggie C. Y., Rotter, Jerome I., Weinreb, Robert N., Li, Zheng, Allingham, R. Rand, Nag, Abhishek, Hysi, Pirro G., Meester-Smoor, Magda A., Wiggs, Janey L, Hauser, Michael A., Hammond, Christopher J., Lemij, Hans G., Loos, Ruth J. F., van Duijn, Cornelia M., Thiadens, Alberta A. H. J., Klaver, Caroline C. W.
Publicado 2018