Metabolic changes during exclusive enteral nutrition in pediatric Crohn’s disease patients

por Marques, Jair G., Schwerd, Tobias, Bufler, Philip, Koletzko, Sibylle, Koletzko, Berthold
Publicado 2022

Epstein–Barr Virus Prevalence at Diagnosis and Seroconversion during Follow-Up in Pediatric Inflammatory Bowel Disease

por Bachmann, Jennifer, Le Thi, Giang, Brückner, Annecarin, Kalteis, Anna-Lena, Schwerd, Tobias, Koletzko, Sibylle, Lurz, Eberhard
Publicado 2021

Esophageal Perforation and EVAC in Pediatric Patients: A Case Series of Four Children

por Ritz, Laura Antonia, Hajji, Mohammad Samer, Schwerd, Tobias, Koletzko, Sibylle, von Schweinitz, Dietrich, Lurz, Eberhard, Hubertus, Jochen
Publicado 2021

Metabolomic Signatures in Pediatric Crohn’s Disease Patients with Mild or Quiescent Disease Treated with Partial Enteral Nutrition: A Feasibility Study

por Marques, Jair Gonzalez, Shokry, Engy, Frivolt, Klara, Werkstetter, Katharina Julia, Brückner, Annecarin, Schwerd, Tobias, Koletzko, Sibylle, Koletzko, Berthold
Publicado 2020

Following Pediatric and Adult IBD Patients through the COVID-19 Pandemic: Changes in Psychosocial Burden and Perception of Infection Risk and Harm over Time

por Koletzko, Leandra, Klucker, Elisabeth, Le Thi, Thu Giang, Breiteneicher, Simone, Rubio-Acero, Raquel, Neuhaus, Lukas, Stark, Reneé G., Standl, Marie, Wieser, Andreas, Török, Helga, Koletzko, Sibylle, Schwerd, Tobias
Publicado 2021

Is Autologous Fecal Microbiota Transfer after Exclusive Enteral Nutrition in Pediatric Crohn’s Disease Patients Rational and Feasible? Data from a Feasibility Test

por Hoelz, Hannes, Heetmeyer, Jeannine, Tsakmaklis, Anastasia, Hiergeist, Andreas, Siebert, Kolja, De Zen, Federica, Häcker, Deborah, Metwaly, Amira, Neuhaus, Klaus, Gessner, André, Vehreschild, Maria J. G. T., Haller, Dirk, Schwerd, Tobias
Publicado 2023

Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation

por Riffelmacher, Thomas, Clarke, Alexander, Richter, Felix C., Stranks, Amanda, Pandey, Sumeet, Danielli, Sara, Hublitz, Philip, Yu, Zhanru, Johnson, Errin, Schwerd, Tobias, McCullagh, James, Uhlig, Holm, Jacobsen, Sten Eirik W., Simon, Anna Katharina
Publicado 2017

Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors

por Canning, Peter, Ruan, Qui, Schwerd, Tobias, Hrdinka, Matous, Maki, Jenny L., Saleh, Danish, Suebsuwong, Chalada, Ray, Soumya, Brennan, Paul E., Cuny, Gregory D., Uhlig, Holm H., Gyrd-Hansen, Mads, Degterev, Alexei, Bullock, Alex N.
Publicado 2015

Valosin-containing protein-regulated endoplasmic reticulum stress causes NOD2-dependent inflammatory responses

por Ghalandary, Maryam, Li, Yue, Fröhlich, Thomas, Magg, Thomas, Liu, Yanshan, Rohlfs, Meino, Hollizeck, Sebastian, Conca, Raffaele, Schwerd, Tobias, Uhlig, Holm H., Bufler, Philip, Koletzko, Sibylle, Muise, Aleixo M., Snapper, Scott B., Hauck, Fabian, Klein, Christoph, Kotlarz, Daniel
Publicado 2022

Anti-TNF therapy for inflammatory bowel disease in patients with neurodegenerative Niemann-Pick disease Type C

por Williams, Isabelle, Pandey, Sumeet, Haller, Wolfram, Huynh, Hien Quoc, Chan, Alicia, Düeker, Gesche, Bettels, Ruth, Peyrin-Biroulet, Laurent, Dike, Chinenye R., DeGeeter, Catherine, Smith, David, Al Eisa, Nada, Platt, Nick, Marquardt, Thorsten, Schwerd, Tobias, Platt, Frances M., Uhlig, Holm H.
Publicado 2022

Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease

por Metwaly, Amira, Jovic, Jelena, Waldschmitt, Nadine, Khaloian, Sevana, Heimes, Helena, Häcker, Deborah, Ahmed, Mohamed, Hammoudi, Nassim, Le Bourhis, Lionel, Mayorgas, Aida, Siebert, Kolja, Basic, Marijana, Schwerd, Tobias, Allez, Matthieu, Panes, Julian, Salas, Azucena, Bleich, André, Zeissig, Sebastian, Schnupf, Pamela, Cominelli, Fabio, Haller, Dirk
Publicado 2023

Selective loss of function variants in IL6ST cause Hyper-IgE syndrome with distinct impairments of T-cell phenotype and function

por Shahin, Tala, Aschenbrenner, Dominik, Cagdas, Deniz, Bal, Sevgi Köstel, Conde, Cecilia Domínguez, Garncarz, Wojciech, Medgyesi, David, Schwerd, Tobias, Karaatmaca, Betül, Cetinkaya, Pınar Gur, Esenboga, Saliha, Twigg, Stephen R. F., Cant, Andrew, Wilkie, Andrew O. M., Tezcan, Ilhan, Uhlig, Holm H., Boztug, Kaan
Publicado 2019

A variant in IL6ST with a selective IL-11 signaling defect in human and mouse

por Schwerd, Tobias, Krause, Freia, Twigg, Stephen R. F., Aschenbrenner, Dominik, Chen, Yin-Huai, Borgmeyer, Uwe, Müller, Miryam, Manrique, Santiago, Schumacher, Neele, Wall, Steven A., Jung, Jonathan, Damm, Timo, Glüer, Claus-Christian, Scheller, Jürgen, Rose-John, Stefan, Jones, E. Yvonne, Laurence, Arian, Wilkie, Andrew O. M., Schmidt-Arras, Dirk, Uhlig, Holm H.
Publicado 2020

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2

por Mukhopadhyay, Subhankar, Heinz, Eva, Porreca, Immacolata, Alasoo, Kaur, Yeung, Amy, Yang, Huei-Ting, Schwerd, Tobias, Forbester, Jessica L., Hale, Christine, Agu, Chukwuma A., Choi, Yoon Ha, Rodrigues, Julia, Capitani, Melania, Jostins-Dean, Luke, Thomas, David C., Travis, Simon, Gaffney, Daniel, Skarnes, William C., Thomson, Nicholas, Uhlig, Holm H., Dougan, Gordon, Powrie, Fiona
Publicado 2019

NBAS Variants Are Associated with Quantitative and Qualitative NK and B Cell Deficiency

por Lenz, Dominic, Pahl, Jens, Hauck, Fabian, Alameer, Seham, Balasubramanian, Meena, Baric, Ivo, Boy, Nikolas, Church, Joseph A., Crushell, Ellen, Dick, Anke, Distelmaier, Felix, Gujar, Jidnyasa, Indolfi, Giuseppe, Lurz, Eberhard, Peters, Bianca, Schwerd, Tobias, Serranti, Daniele, Kölker, Stefan, Klein, Christoph, Hoffmann, Georg F., Prokisch, Holger, Greil, Johann, Cerwenka, Adelheid, Giese, Thomas, Staufner, Christian
Publicado 2021

Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease

por Schwerd, Tobias, Pandey, Sumeet, Yang, Huei-Ting, Bagola, Katrin, Jameson, Elisabeth, Jung, Jonathan, Lachmann, Robin H, Shah, Neil, Patel, Smita Y, Booth, Claire, Runz, Heiko, Düker, Gesche, Bettels, Ruth, Rohrbach, Marianne, Kugathasan, Subra, Chapel, Helen, Keshav, Satish, Elkadri, Abdul, Platt, Nick, Muise, Alexio M, Koletzko, Sibylle, Xavier, Ramnik J, Marquardt, Thorsten, Powrie, Fiona, Wraith, James E, Gyrd-Hansen, Mads, Platt, Frances M, Uhlig, Holm H
Publicado 2017

A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis

por Schwerd, Tobias, Twigg, Stephen R.F., Aschenbrenner, Dominik, Manrique, Santiago, Miller, Kerry A., Taylor, Indira B., Capitani, Melania, McGowan, Simon J., Sweeney, Elizabeth, Weber, Astrid, Chen, Liye, Bowness, Paul, Riordan, Andrew, Cant, Andrew, Freeman, Alexandra F., Milner, Joshua D., Holland, Steven M., Frede, Natalie, Müller, Miryam, Schmidt-Arras, Dirk, Grimbacher, Bodo, Wall, Steven A., Jones, E. Yvonne, Wilkie, Andrew O.M., Uhlig, Holm H.
Publicado 2017

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

por Serra, Eva Gonçalves, Schwerd, Tobias, Moutsianas, Loukas, Cavounidis, Athena, Fachal, Laura, Pandey, Sumeet, Kammermeier, Jochen, Croft, Nicholas M., Posovszky, Carsten, Rodrigues, Astor, Russell, Richard K., Barakat, Farah, Auth, Marcus K. H., Heuschkel, Robert, Zilbauer, Matthias, Fyderek, Krzysztof, Braegger, Christian, Travis, Simon P., Satsangi, Jack, Parkes, Miles, Thapar, Nikhil, Ferry, Helen, Matte, Julie C., Gilmour, Kimberly C., Wedrychowicz, Andrzej, Sullivan, Peter, Moore, Carmel, Sambrook, Jennifer, Ouwehand, Willem, Roberts, David, Danesh, John, Baeumler, Toni A., Fulga, Tudor A., Carrami, Eli M., Ahmed, Ahmed, Wilson, Rachel, Barrett, Jeffrey C., Elkadri, Abdul, Griffiths, Anne M., Snapper, Scott B., Shah, Neil, Muise, Aleixo M., Wilson, David C., Uhlig, Holm H., Anderson, Carl A.
Publicado 2020

Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

por Serra, Eva Gonçalves, Schwerd, Tobias, Moutsianas, Loukas, Cavounidis, Athena, Fachal, Laura, Pandey, Sumeet, Kammermeier, Jochen, Croft, Nicholas M., Posovszky, Carsten, Rodrigues, Astor, Russell, Richard K., Barakat, Farah, Auth, Marcus K. H., Heuschkel, Robert, Zilbauer, Matthias, Fyderek, Krzysztof, Braegger, Christian, Travis, Simon P., Satsangi, Jack, Parkes, Miles, Thapar, Nikhil, Ferry, Helen, Matte, Julie C., Gilmour, Kimberly C., Wedrychowicz, Andrzej, Sullivan, Peter, Moore, Carmel, Sambrook, Jennifer, Ouwehand, Willem, Roberts, David, Danesh, John, Baeumler, Toni A., Fulga, Tudor A., Carrami, Eli M, Ahmed, Ahmed, Wilson, Rachel, Barrett, Jeffrey C., Elkadri, Abdul, Griffiths, Anne M., Snapper, Scott B., Shah, Neil, Muise, Aleixo M., Wilson, David C., Uhlig, Holm H., Anderson, Carl A.
Publicado 2022