Small Molecules Targeting H3K9 Methylation Prevent Silencing of Reactivated FMR1 Alleles in Fragile X Syndrome Patient Derived Cells

por Kumari, Daman, Sciascia, Nicholas, Usdin, Karen
Publicado 2020

CGG-repeat dynamics and FMR1 gene silencing in fragile X syndrome stem cells and stem cell-derived neurons

por Zhou, Yifan, Kumari, Daman, Sciascia, Nicholas, Usdin, Karen
Publicado 2016

Repeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disorders

por Usdin, Karen, Hayward, Bruce E., Kumari, Daman, Lokanga, Rachel A., Sciascia, Nicholas, Zhao, Xiao-Nan
Publicado 2014

Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity

por Sciascia, Nicholas, Wu, Wei, Zong, Dali, Sun, Yilun, Wong, Nancy, John, Sam, Wangsa, Darawalee, Ried, Thomas, Bunting, Samuel F, Pommier, Yves, Nussenzweig, André
Publicado 2020

ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis

por Paiano, Jacob, Wu, Wei, Yamada, Shintaro, Sciascia, Nicholas, Callen, Elsa, Paola Cotrim, Ana, Deshpande, Rajashree A., Maman, Yaakov, Day, Amanda, Paull, Tanya T., Nussenzweig, André
Publicado 2020