Specificity may be overrated in cancer immunotherapy: Getting to know the nonspecific side of memory T Cells

por Sckisel, Gail D., Murphy, William J.
Publicado 2012

Monoclonal antibody therapies targeting immune checkpoints induce fatal anaphylactic reactions in a murine model of breast cancer

por Mall, Christine, Sckisel, Gail D, Mirsoian, Annie, Grossenbacher, Steven K, Murphy, William J
Publicado 2014

Immunoediting and Antigen Loss: Overcoming the Achilles Heel of Immunotherapy with Antigen Non-Specific Therapies

por Monjazeb, Arta Monir, Zamora, Anthony E., Grossenbacher, Steven K., Mirsoian, Annie, Sckisel, Gail D., Murphy, William J.
Publicado 2013

Combined radiotherapy and immunotherapy using CPG oligodeoxynucleotides and indolamine 2,3 dioxygenase (IDO) blockade

por Monjazeb, Arta M, Grossenbacher, Steven K, Sckisel, Gail D, Canter, Robert, Sparger, Ellen E, Culp, William, Kent, Michael S, Murphy, William J
Publicado 2013

Bystander memory CD8 T cell proliferation after anti-CD40/IL-2 treatment is independent of CD4 T cells

por Grossenbacher, Steven K, Monjazeb, Arta M, Tietze, Julia, Sckisel, Gail D, Mirsoian, Annie, Hsiao, Hui-Hua, Koehn, Brent, Wilkins, Danice, Blazer, Bruce R, Murphy, William J
Publicado 2013

Mechanical Disruption of Tumors by Iron Particles and Magnetic Field Application Results in Increased Anti-Tumor Immune Responses

por Bouchlaka, Myriam N., Sckisel, Gail D., Wilkins, Danice, Maverakis, Emanual, Monjazeb, Arta M., Fung, Maxwell, Welniak, Lisbeth, Redelman, Doug, Fuchs, Alan, Evrensel, Cahit A., Murphy, William J.
Publicado 2012

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

por Sckisel, Gail D., Mirsoian, Annie, Minnar, Christine M., Crittenden, Marka, Curti, Brendan, Chen, Jane Q., Blazar, Bruce R., Borowsky, Alexander D., Monjazeb, Arta M., Murphy, William J.
Publicado 2017

Bystander Activation and Anti-Tumor Effects of CD8+ T Cells Following Interleukin-2 Based Immunotherapy Is Independent of CD4+ T Cell Help

por Monjazeb, Arta M., Tietze, Julia K., Grossenbacher, Steven K., Hsiao, Hui-Hua, Zamora, Anthony E., Mirsoian, Annie, Koehn, Brent, Blazar, Bruce R., Weiss, Jonathan M., Wiltrout, Robert H., Sckisel, Gail D., Murphy, William J.
Publicado 2014

Engineered IL-21 Cytokine Muteins Fused to Anti-PD-1 Antibodies Can Improve CD8+ T Cell Function and Anti-tumor Immunity

por Shen, Shanling, Sckisel, Gail, Sahoo, Anupama, Lalani, Almin, Otter, Doug Den, Pearson, Josh, DeVoss, Jason, Cheng, Jay, Casey, Stephanie C., Case, Ryan, Yang, Melissa, Low, Ray, Daris, Mark, Fan, Bin, Agrawal, Neeraj J., Ali, Khaled
Publicado 2020

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

por Mirsoian, Annie, Bouchlaka, Myriam N., Sckisel, Gail D., Chen, Mingyi, Pai, Chien-Chun Steven, Maverakis, Emanuel, Spencer, Richard G., Fishbein, Kenneth W., Siddiqui, Sana, Monjazeb, Arta M., Martin, Bronwen, Maudsley, Stuart, Hesdorffer, Charles, Ferrucci, Luigi, Longo, Dan L., Blazar, Bruce R., Wiltrout, Robert H., Taub, Dennis D., Murphy, William J.
Publicado 2014

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

por Bouchlaka, Myriam N., Sckisel, Gail D., Chen, Mingyi, Mirsoian, Annie, Zamora, Anthony E., Maverakis, Emanual, Wilkins, Danice E.C., Alderson, Kory L., Hsiao, Hui-Hua, Weiss, Jonathan M., Monjazeb, Arta M., Hesdorffer, Charles, Ferrucci, Luigi, Longo, Dan L., Blazar, Bruce R., Wiltrout, Robert H., Redelman, Doug, Taub, Dennis D., Murphy, William J.
Publicado 2013