Ba/F3 transformation assays

por Kong, Kathleen, Ng, Patrick Kwok-Shing, Scott, Kenneth L.
Publicado 2017

IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion.

por Bajaj, Rakhee, Kundu, Samrat T., Grzeskowiak, Caitlin L., Fradette, Jared J., Scott, Kenneth L., Creighton, Chad J., Gibbons, Don L.
Publicado 2020

The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing

por Hu, Xiaohui, Harvey, Samuel E., Zheng, Rong, Lyu, Jingyi, Grzeskowiak, Caitlin L., Powell, Emily, Piwnica-Worms, Helen, Scott, Kenneth L., Cheng, Chonghui
Publicado 2020

HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome

por Wardwell-Ozgo, Joanna, Dogruluk, Turgut, Gifford, Armel, Zhang, Yiqun, Heffernan, Timothy P., van Doorn, Remco, Creighton, Chad J., Chin, Lynda, Scott, Kenneth L.
Publicado 2013

TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins

por Kundu, Samrat T., Grzeskowiak, Caitlin L., Fradette, Jared J., Gibson, Laura A., Rodriguez, Leticia B., Creighton, Chad J., Scott, Kenneth L., Gibbons, Don L.
Publicado 2018

Cancer driver mutation prediction through Bayesian integration of multi-omic data

por Wang, Zixing, Ng, Kwok-Shing, Chen, Tenghui, Kim, Tae-Beom, Wang, Fang, Shaw, Kenna, Scott, Kenneth L., Meric-Bernstam, Funda, Mills, Gordon B., Chen, Ken
Publicado 2018

Daam2 driven degradation of VHL promotes gliomagenesis

por Zhu, Wenyi, Krishna, Saritha, Garcia, Cristina, Lin, Chia-Ching John, Mitchell, Bartley D, Scott, Kenneth L, Mohila, Carrie A, Creighton, Chad J, Yoo, Seung-Hee, Lee, Hyun Kyoung, Deneen, Benjamin
Publicado 2017

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies

por Ip, Carman K. M., Ng, Patrick K. S., Jeong, Kang Jin, Shao, S. H., Ju, Zhenlin, Leonard, P. G., Hua, Xu, Vellano, Christopher P., Woessner, Richard, Sahni, Nidhi, Scott, Kenneth L., Mills, Gordon B.
Publicado 2018

Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

por Tsang, Yiu Huen, Wang, Yumeng, Kong, Kathleen, Grzeskowiak, Caitlin, Zagorodna, Oksana, Dogruluk, Turgut, Lu, Hengyu, Villafane, Nicole, Bhavana, Venkata Hemanjani, Moreno, Daniela, Elsea, Sarah H, Liang, Han, Mills, Gordon B, Scott, Kenneth L
Publicado 2020

Integrative Genome Comparison of Primary and Metastatic Melanomas

por Kabbarah, Omar, Nogueira, Cristina, Feng, Bin, Nazarian, Rosalynn M., Bosenberg, Marcus, Wu, Min, Scott, Kenneth L., Kwong, Lawrence N., Xiao, Yonghong, Cordon-Cardo, Carlos, Granter, Scott R., Ramaswamy, Sridhar, Golub, Todd, Duncan, Lyn M., Wagner, Stephan N., Brennan, Cameron, Chin, Lynda
Publicado 2010

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

por Wang, Yumeng, Xu, Xiaoyan, Yu, Shuangxing, Jeong, Kang Jin, Zhou, Zhicheng, Han, Leng, Tsang, Yiu Huen, Li, Jun, Chen, Hu, Mangala, Lingegowda S., Yuan, Yuan, Eterovic, A. Karina, Lu, Yiling, Sood, Anil K., Scott, Kenneth L., Mills, Gordon B., Liang, Han
Publicado 2017

GOLPH3 modulates mTOR signaling and rapamycin sensitivity in cancer

por Scott, Kenneth L., Kabbarah, Omar, Liang, Mei-Chih, Ivanova, Elena, Anagnostou, Valsamo, Wu, Joyce, Dhakal, Sabin, Wu, Min, Chen, Shujuan, Feinberg, Tamar, Huang, Joseph, Saci, Abdel, Widlund, Hans R., Fisher, David E., Xiao, Yonghong, Rimm, David L., Protopopov, Alexei, Wong, Kwok-Kin, Chin, Lynda
Publicado 2009

Polygenic in vivo validation of cancer mutations using transposons

por Chew, Su Kit, Lu, Dong, Campos, Lia S, Scott, Kenneth L, Saci, Abdel, Wang, Juexuan, Collinson, Adam, Raine, Keiran, Hinton, Jonathan, Teague, Jon W, Jones, David, Menzies, Andrew, Butler, Adam P, Gamble, John, O’Meara, Sarah, McLaren, Stuart, Chin, Lynda, Liu, Pentao, Futreal, P Andrew
Publicado 2014

A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis

por Powell, Emily, Shao, Jiansu, Picon, Hector M., Bristow, Christopher, Ge, Zhongqi, Peoples, Michael, Robinson, Frederick, Jeter-Jones, Sabrina L., Schlosberg, Christopher, Grzeskowiak, Caitlin L., Yang, Fei, Wu, Yun, Wistuba, Ignacio, Moulder, Stacy L., Symmans, William F., Scott, Kenneth L., Edwards, John R., Liang, Han, Heffernan, Timothy P., Piwnica-Worms, Helen
Publicado 2018

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

por Grzeskowiak, Caitlin L., Kundu, Samrat T., Mo, Xiulei, Ivanov, Andrei A., Zagorodna, Oksana, Lu, Hengyu, Chapple, Richard H., Tsang, Yiu Huen, Moreno, Daniela, Mosqueda, Maribel, Eterovic, Karina, Fradette, Jared J., Ahmad, Sumreen, Chen, Fengju, Chong, Zechen, Chen, Ken, Creighton, Chad J., Fu, Haian, Mills, Gordon B., Gibbons, Don L., Scott, Kenneth L.
Publicado 2018

Functional annotation of rare gene aberration drivers of pancreatic cancer

por Tsang, Yiu Huen, Dogruluk, Turgut, Tedeschi, Philip M., Wardwell-Ozgo, Joanna, Lu, Hengyu, Espitia, Maribel, Nair, Nikitha, Minelli, Rosalba, Chong, Zechen, Chen, Fengju, Chang, Qing Edward, Dennison, Jennifer B., Dogruluk, Armel, Li, Min, Ying, Haoqiang, Bertino, Joseph R., Gingras, Marie-Claude, Ittmann, Michael, Kerrigan, John, Chen, Ken, Creighton, Chad J., Eterovic, Karina, Mills, Gordon B., Scott, Kenneth L.
Publicado 2016

RNA editing derived epitopes function as cancer antigens to elicit immune responses

por Zhang, Minying, Fritsche, Jens, Roszik, Jason, Williams, Leila J., Peng, Xinxin, Chiu, Yulun, Tsou, Chih-Chiang, Hoffgaard, Franziska, Goldfinger, Valentina, Schoor, Oliver, Talukder, Amjad, Forget, Marie A., Haymaker, Cara, Bernatchez, Chantale, Han, Leng, Tsang, Yiu-Huen, Kong, Kathleen, Xu, Xiaoyan, Scott, Kenneth L., Singh-Jasuja, Harpreet, Lizee, Greg, Liang, Han, Weinschenk, Toni, Mills, Gordon B., Hwu, Patrick
Publicado 2018

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

por Liang, Han, Cheung, Lydia W.T., Li, Jie, Ju, Zhenlin, Yu, Shuangxing, Stemke-Hale, Katherine, Dogruluk, Turgut, Lu, Yiling, Liu, Xiuping, Gu, Chao, Guo, Wei, Scherer, Steven E., Carter, Hannah, Westin, Shannon N., Dyer, Mary D., Verhaak, Roeland G.W., Zhang, Fan, Karchin, Rachel, Liu, Chang-Gong, Lu, Karen H., Broaddus, Russell R., Scott, Kenneth L., Hennessy, Bryan T., Mills, Gordon B.
Publicado 2012

Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2

por Choi, Byung-Kwon, Dayaram, Tajhal, Parikh, Neha, Wilkins, Angela D., Nagarajan, Meena, Novikov, Ilya B., Bachman, Benjamin J., Jung, Sung Yun, Haas, Peter J., Labrie, Jacques L., Pickering, Curtis R., Adikesavan, Anbu K., Regenbogen, Sam, Kato, Linda, Lelescu, Ana, Buchovecky, Christie M., Zhang, Houyin, Bao, Sheng Hua, Boyer, Stephen, Weber, Griff, Scott, Kenneth L., Chen, Ying, Spangler, Scott, Donehower, Lawrence A., Lichtarge, Olivier
Publicado 2018

A functional genomic approach to actionable gene fusions for precision oncology

por Li, Jun, Lu, Hengyu, Ng, Patrick Kwok-Shing, Pantazi, Angeliki, Ip, Carman Ka Man, Jeong, Kang Jin, Amador, Bianca, Tran, Richard, Tsang, Yiu Huen, Yang, Lixing, Song, Xingzhi, Dogruluk, Turgut, Ren, Xiaojia, Hadjipanayis, Angela, Bristow, Christopher A., Lee, Semin, Kucherlapati, Melanie, Parfenov, Michael, Tang, Jiabin, Seth, Sahil, Mahadeshwar, Harshad S., Mojumdar, Kamalika, Zeng, Dong, Zhang, Jianhua, Protopopov, Alexei, Seidman, Jonathan G., Creighton, Chad J., Lu, Yiling, Sahni, Nidhi, Shaw, Kenna R., Meric-Bernstam, Funda, Futreal, Andrew, Chin, Lynda, Scott, Kenneth L., Kucherlapati, Raju, Mills, Gordon B., Liang, Han
Publicado 2022