Prediction of suicidal ideation risk in a prospective cohort study of medical interns

por Malone, Tyler L., Zhao, Zhou, Liu, Tzu-Ying, Song, Peter X. K., Sen, Srijan, Scott, Laura J.
Publicado 2021

Broad-Enrich: functional interpretation of large sets of broad genomic regions

por Cavalcante, Raymond G., Lee, Chee, Welch, Ryan P., Patil, Snehal, Weymouth, Terry, Scott, Laura J., Sartor, Maureen A.
Publicado 2014

ChIP-Enrich: gene set enrichment testing for ChIP-seq data

por Welch, Ryan P., Lee, Chee, Imbriano, Paul M., Patil, Snehal, Weymouth, Terry E., Smith, R. Alex, Scott, Laura J., Sartor, Maureen A.
Publicado 2014

Ancestry-agnostic estimation of DNA sample contamination from sequence reads

por Zhang, Fan, Flickinger, Matthew, Taliun, Sarah A. Gagliano, Abecasis, Gonçalo R., Scott, Laura J., McCaroll, Steven A., Pato, Carlos N., Boehnke, Michael, Kang, Hyun Min
Publicado 2020

Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans

por Carlson, Jedidiah, Locke, Adam E., Flickinger, Matthew, Zawistowski, Matthew, Levy, Shawn, Myers, Richard M., Boehnke, Michael, Kang, Hyun Min, Scott, Laura J., Li, Jun Z., Zöllner, Sebastian
Publicado 2018

Cabbage and Sauerkraut Consumption in Adolescence and Adulthood and Breast Cancer Risk among US-Resident Polish Migrant Women

por Pathak, Dorothy Rybaczyk, Stein, Aryeh D., He, Jian-Ping, Noel, Mary M., Hembroff, Larry, Nelson, Dorothy A., Vigneau, Fawn, Shen, Tiefu, Scott, Laura J., Charzewska, Jadwiga, Wajszczyk, Bożena, Clark, Karen, Rybaczyk, Leszek A., Pathak, Bogdan A., Błaszczyk, Dorota, Bankowski, Ann, Willett, Walter C.
Publicado 2021

Tissue-specific alternative splicing of TCF7L2

por Prokunina-Olsson, Ludmila, Welch, Cullan, Hansson, Ola, Adhikari, Neeta, Scott, Laura J., Usher, Nicolle, Tong, Maurine, Sprau, Andrew, Swift, Amy, Bonnycastle, Lori L., Erdos, Michael R., He, Zhi, Saxena, Richa, Harmon, Brennan, Kotova, Olga, Hoffman, Eric P., Altshuler, David, Groop, Leif, Boehnke, Michael, Collins, Francis S., Hall, Jennifer L.
Publicado 2009

Proteome-Wide Association Studies for Blood Lipids and Comparison with Transcriptome-Wide Association Studies

por Zhang, Daiwei, Gao, Boran, Feng, Qidi, Manichaikul, Ani, Peloso, Gina M., Tracy, Russell P., Durda, Peter, Taylor, Kent D., Liu, Yongmei, Johnson, W. Craig, Gabriel, Stacey, Gupta, Namrata, Smith, Joshua D., Aguet, Francois, Ardlie, Kristin G., Blackwell, Thomas W., Gerszten, Robert E., Rich, Stephen S., Rotter, Jerome I., Scott, Laura J., Zhou, Xiang, Lee, Seunggeun
Publicado 2023

Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle

por Taylor, D. Leland, Jackson, Anne U., Narisu, Narisu, Hemani, Gibran, Erdos, Michael R., Chines, Peter S., Swift, Amy, Idol, Jackie, Didion, John P., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Parker, Stephen C. J., Koistinen, Heikki A., Davey Smith, George, Boehnke, Michael, Scott, Laura J., Birney, Ewan, Collins, Francis S.
Publicado 2019

Comprehensive Association Study of Type 2 Diabetes and Related Quantitative Traits With 222 Candidate Genes

por Gaulton, Kyle J., Willer, Cristen J., Li, Yun, Scott, Laura J., Conneely, Karen N., Jackson, Anne U., Duren, William L., Chines, Peter S., Narisu, Narisu, Bonnycastle, Lori L., Luo, Jingchun, Tong, Maurine, Sprau, Andrew G., Pugh, Elizabeth W., Doheny, Kimberly F., Valle, Timo T., Abecasis, Gonçalo R., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis S., Boehnke, Michael, Mohlke, Karen L.
Publicado 2008

ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition

por El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.
Publicado 2020

Interactions between genetic variation and cellular environment in skeletal muscle gene expression

por Taylor, D. Leland, Knowles, David A., Scott, Laura J., Ramirez, Andrea H., Casale, Francesco Paolo, Wolford, Brooke N., Guan, Li, Varshney, Arushi, Albanus, Ricardo D’Oliveira, Parker, Stephen C. J., Narisu, Narisu, Chines, Peter S., Erdos, Michael R., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Stegle, Oliver, Boehnke, Michael, Birney, Ewan, Collins, Francis S.
Publicado 2018

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

por Spracklen, Cassandra N., Iyengar, Apoorva K., Vadlamudi, Swarooparani, Raulerson, Chelsea K., Jackson, Anne U., Brotman, Sarah M., Wu, Ying, Cannon, Maren E., Davis, James P., Crain, Aaron T., Currin, Kevin W., Perrin, Hannah J., Narisu, Narisu, Stringham, Heather M., Fuchsberger, Christian, Locke, Adam E., Welch, Ryan P., Kuusisto, Johanna K., Pajukanta, Päivi, Scott, Laura J., Li, Yun, Collins, Francis S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L.
Publicado 2020

Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk

por Yin, Xianyong, Bose, Debraj, Kwon, Annie, Hanks, Sarah C., Jackson, Anne U., Stringham, Heather M., Welch, Ryan, Oravilahti, Anniina, Fernandes Silva, Lilian, Locke, Adam E., Fuchsberger, Christian, Service, Susan K., Erdos, Michael R., Bonnycastle, Lori L., Kuusisto, Johanna, Stitziel, Nathan O., Hall, Ira M., Morrison, Jean, Ripatti, Samuli, Palotie, Aarno, Freimer, Nelson B., Collins, Francis S., Mohlke, Karen L., Scott, Laura J., Fauman, Eric B., Burant, Charles, Boehnke, Michael, Laakso, Markku, Wen, Xiaoquan
Publicado 2022

Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q

por Prokopenko, Inga, Zeggini, Eleftheria, Hanson, Robert L., Mitchell, Braxton D., Rayner, N. William, Akan, Pelin, Baier, Leslie, Das, Swapan K., Elliott, Katherine S., Fu, Mao, Frayling, Timothy M., Groves, Christopher J., Gwilliam, Rhian, Scott, Laura J., Voight, Benjamin F., Hattersley, Andrew T., Hu, Cheng, Morris, Andrew D., Ng, Maggie, Palmer, Colin N.A., Tello-Ruiz, Marcela, Vaxillaire, Martine, Wang, Cong-rong, Stein, Lincoln, Chan, Juliana, Jia, Weiping, Froguel, Philippe, Elbein, Steven C., Deloukas, Panos, Bogardus, Clifton, Shuldiner, Alan R., McCarthy, Mark I.
Publicado 2009

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

por Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.
Publicado 2016

Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits

por Brotman, Sarah M., El-Sayed Moustafa, Julia S., Guan, Li, Broadaway, K. Alaine, Wang, Dongmeng, Jackson, Anne U., Welch, Ryan, Currin, Kevin W., Tomlinson, Max, Vadlamudi, Swarooparani, Stringham, Heather M., Roberts, Amy L., Lakka, Timo A., Oravilahti, Anniina, Silva, Lilian Fernandes, Narisu, Narisu, Erdos, Michael R., Yan, Tingfen, Bonnycastle, Lori L., Raulerson, Chelsea K., Raza, Yasrab, Yan, Xinyu, Parker, Stephen C.J., Kuusisto, Johanna, Pajukanta, Päivi, Tuomilehto, Jaakko, Collins, Francis S., Boehnke, Michael, Love, Michael I., Koistinen, Heikki A., Laakso, Markku, Mohlke, Karen L., Small, Kerrin S., Scott, Laura J.
Publicado 2023

ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition—implications for COVID-19

por El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Acors, Sam, Kouphou, Neophytos, Wadge, Samuel, Duncan, Emma L., Steves, Claire J., Doores, Katie J., Malim, Michael H., Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.
Publicado 2022

Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

por Viñuela, Ana, Varshney, Arushi, van de Bunt, Martijn, Prasad, Rashmi B., Asplund, Olof, Bennett, Amanda, Boehnke, Michael, Brown, Andrew A., Erdos, Michael R., Fadista, João, Hansson, Ola, Hatem, Gad, Howald, Cédric, Iyengar, Apoorva K., Johnson, Paul, Krus, Ulrika, MacDonald, Patrick E., Mahajan, Anubha, Manning Fox, Jocelyn E., Narisu, Narisu, Nylander, Vibe, Orchard, Peter, Oskolkov, Nikolay, Panousis, Nikolaos I., Payne, Anthony, Stitzel, Michael L., Vadlamudi, Swarooparani, Welch, Ryan, Collins, Francis S., Mohlke, Karen L., Gloyn, Anna L., Scott, Laura J., Dermitzakis, Emmanouil T., Groop, Leif, Parker, Stephen C. J., McCarthy, Mark I.
Publicado 2020

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

por Yin, Xianyong, Chan, Lap Sum, Bose, Debraj, Jackson, Anne U., VandeHaar, Peter, Locke, Adam E., Fuchsberger, Christian, Stringham, Heather M., Welch, Ryan, Yu, Ketian, Fernandes Silva, Lilian, Service, Susan K., Zhang, Daiwei, Hector, Emily C., Young, Erica, Ganel, Liron, Das, Indraniel, Abel, Haley, Erdos, Michael R., Bonnycastle, Lori L., Kuusisto, Johanna, Stitziel, Nathan O., Hall, Ira M., Wagner, Gregory R., Kang, Jian, Morrison, Jean, Burant, Charles F., Collins, Francis S., Ripatti, Samuli, Palotie, Aarno, Freimer, Nelson B., Mohlke, Karen L., Scott, Laura J., Wen, Xiaoquan, Fauman, Eric B., Laakso, Markku, Boehnke, Michael
Publicado 2022