Integrating pathology into human disease modelling – how to eat the elephant

por Scudamore, Cheryl L.
Publicado 2014

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?

por Petrova, Tsvetana, Bennett, Kyle, Nanda, Sambit, Strickson, Sam, Scudamore, Cheryl L., Prescott, Alan R., Cohen, Philip
Publicado 2022

Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice

por Alliouachene, Samira, Bilanges, Benoit, Chaussade, Claire, Pearce, Wayne, Foukas, Lazaros C., Scudamore, Cheryl L., Moniz, Larissa S., Vanhaesebroeck, Bart
Publicado 2016

Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles

por Elshorbagy, Amany K., Jernerén, Fredrik, Scudamore, Cheryl L., McMurray, Fiona, Cater, Heather, Hough, Tertius, Cox, Roger, Refsum, Helga
Publicado 2016

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

por Stark, Anne-Katrien, Davenport, Elizabeth C. M., Patton, Daniel T., Scudamore, Cheryl L., Vanhaesebroeck, Bart, Veldhoen, Marc, Garden, Oliver A., Okkenhaug, Klaus
Publicado 2020

Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis

por Verbiest, Tom, Finnon, Rosemary, Brown, Natalie, Cruz-Garcia, Lourdes, Finnon, Paul, O’Brien, Grainne, Ross, Eleanor, Bouffler, Simon, Scudamore, Cheryl L., Badie, Christophe
Publicado 2018

HOIL‐1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation

por Kelsall, Ian R, McCrory, Elisha H, Xu, Yingqi, Scudamore, Cheryl L, Nanda, Sambit K, Mancebo‐Gamella, Paula, Wood, Nicola T, Knebel, Axel, Matthews, Stephen J, Cohen, Philip
Publicado 2022

High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice

por Podrini, Christine, Cambridge, Emma L., Lelliott, Christopher J., Carragher, Damian M., Estabel, Jeanne, Gerdin, Anna-Karin, Karp, Natasha A., Scudamore, Cheryl L., Ramirez-Solis, Ramiro, White, Jacqueline K.
Publicado 2013

Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues

por Al-Jazzar, Ahmed, Javaheri, Behzad, Prideaux, Matt, Boyde, Alan, Scudamore, Cheryl L., Cherifi, Chahrazad, Hay, Eric, Hopkinson, Mark, Boyd, Michael, Cohen-Solal, Martine, Farquharson, Colin, Pitsillides, Andrew A.
Publicado 2016

Long‐term treatment of cancer‐prone germline PTEN mutant mice with low‐dose rapamycin extends lifespan and delays tumour development

por Tibarewal, Priyanka, Rathbone, Victoria, Constantinou, Georgia, Pearce, Wayne, Adil, Mahreen, Varyova, Zofia, Folkes, Lisa, Hampson, Alix, Classen, Gala Anastasia Electra, Alves, Adriana, Carvalho, Sara, Scudamore, Cheryl L, Vanhaesebroeck, Bart
Publicado 2022

Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance

por Hugill, Alison J., Stewart, Michelle E., Yon, Marianne A., Probert, Fay, Cox, I. Jane, Hough, Tertius A., Scudamore, Cheryl L., Bentley, Liz, Wall, Gary, Wells, Sara E., Cox, Roger D.
Publicado 2015

Inactivation of the PI3K p110δ breaks regulatory T cell-mediated immune tolerance to cancer

por Ali, Khaled, Soond, Dalya R., Pineiro, Roberto, Hagemann, Thorsten, Pearce, Wayne, Lim, Ee Lyn, Bouabe, Hicham, Scudamore, Cheryl L., Hancox, Timothy, Maecker, Heather, Friedman, Lori, Turner, Martin, Okkenhaug, Klaus, Vanhaesebroeck, Bart
Publicado 2014

Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background

por Falcone, Sara, Wisby, Laura, Nicol, Thomas, Blease, Andrew, Starbuck, Becky, Parker, Andrew, Sanderson, Jeremy, Brown, Steve D. M., Scudamore, Cheryl L., Pusey, Charles D., Tam, Frederick W. K., Potter, Paul K.
Publicado 2019

Pharmacological Inhibition of FTO

por McMurray, Fiona, Demetriades, Marina, Aik, WeiShen, Merkestein, Myrte, Kramer, Holger, Andrew, Daniel S., Scudamore, Cheryl L., Hough, Tertius A., Wells, Sara, Ashcroft, Frances M., McDonough, Michael A., Schofield, Christopher J., Cox, Roger D.
Publicado 2015

Gadd45γ and Map3k4 Interactions Regulate Mouse Testis Determination via p38 MAPK-Mediated Control of Sry Expression

por Warr, Nick, Carre, Gwenn-Aël, Siggers, Pam, Faleato, Jessica Vitos, Brixey, Rachel, Pope, Madeleine, Bogani, Debora, Childers, Melissa, Wells, Sara, Scudamore, Cheryl L., Tedesco, Marianna, del Barco Barrantes, Ivan, Nebreda, Angel R., Trainor, Paul A., Greenfield, Andy
Publicado 2012

Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity

por Alliouachene, Samira, Bilanges, Benoit, Chicanne, Gaëtan, Anderson, Karen E., Pearce, Wayne, Ali, Khaled, Valet, Colin, Posor, York, Low, Pei Ching, Chaussade, Claire, Scudamore, Cheryl L., Salamon, Rachel S., Backer, Jonathan M., Stephens, Len, Hawkins, Phill T., Payrastre, Bernard, Vanhaesebroeck, Bart
Publicado 2015

Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors

por Kosti, Paris, Opzoomer, James W., Larios-Martinez, Karen I., Henley-Smith, Rhonda, Scudamore, Cheryl L., Okesola, Mary, Taher, Mustafa Y.M., Davies, David M., Muliaditan, Tamara, Larcombe-Young, Daniel, Woodman, Natalie, Gillett, Cheryl E., Thavaraj, Selvam, Maher, John, Arnold, James N.
Publicado 2021

International Recommendations for Training Future Toxicologic Pathologists Participating in Regulatory-Type, Nonclinical Toxicity Studies

por Bolon, Brad, Barale-Thomas, Erio, Bradley, Alys, Ettlin, Robert A., Franchi, Carla A.S., George, Catherine, Giusti, Anna Maria, Hall, Robert, Jacobsen, Matthew, Konishi, Yoichi, Ledieu, David, Morton, Daniel, Park, Jae-Hak, Scudamore, Cheryl L., Tsuda, Hiroyuki, Vijayasarathi, S.K., Wijnands, Marcel V.W.
Publicado 2010

An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

por Bentley, Liz, Esapa, Christopher T., Nesbit, M. Andrew, Head, Rosie A., Evans, Holly, Lath, Darren, Scudamore, Cheryl L., Hough, Tertius A., Podrini, Christine, Hannan, Fadil M., Fraser, William D., Croucher, Peter I., Brown, Matthew A., Brown, Steve D. M., Cox, Roger D., Thakker, Rajesh V.
Publicado 2014

Targeting of Slc25a21 Is Associated with Orofacial Defects and Otitis Media Due to Disrupted Expression of a Neighbouring Gene

por Maguire, Simon, Estabel, Jeanne, Ingham, Neil, Pearson, Selina, Ryder, Edward, Carragher, Damian M., Walker, Nicolas, Bussell, James, Chan, Wai-In, Keane, Thomas M., Adams, David J., Scudamore, Cheryl L., Lelliott, Christopher J., Ramírez-Solis, Ramiro, Karp, Natasha A., Steel, Karen P., White, Jacqueline K., Gerdin, Anna-Karin
Publicado 2014