Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon

por Sharick, Joe T., Favreau, Peter F., Gillette, Amani A., Sdao, Sophia M., Merrins, Matthew J., Skala, Melissa C.
Publicado 2018

EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance

por Schaid, Michael D., Harrington, Jeffrey M., Kelly, Grant M., Sdao, Sophia M., Merrins, Matthew J., Kimple, Michelle E.
Publicado 2023

CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent K(ATP) channel closure

por Sdao, Sophia M., Ho, Thuong, Poudel, Chetan, Foster, Hannah R., De Leon, Elizabeth R., Adams, Melissa T., Lee, Ji-Hyeon, Blum, Barak, Rane, Sushil G., Merrins, Matthew J.
Publicado 2021

β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the K(ATP) channel

por Foster, Hannah R, Ho, Thuong, Potapenko, Evgeniy, Sdao, Sophia M, Huang, Shih Ming, Lewandowski, Sophie L, VanDeusen, Halena R, Davidson, Shawn M, Cardone, Rebecca L, Prentki, Marc, Kibbey, Richard G, Merrins, Matthew J
Publicado 2022

Pancreatic β-Cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced K(ATP) Channel Activity

por Gregg, Trillian, Poudel, Chetan, Schmidt, Brian A., Dhillon, Rashpal S., Sdao, Sophia M., Truchan, Nathan A., Baar, Emma L., Fernandez, Luis A., Denu, John M., Eliceiri, Kevin W., Rogers, Jeremy D., Kimple, Michelle E., Lamming, Dudley W., Merrins, Matthew J.
Publicado 2016

Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E(2) Signaling and Enhances Diabetic β-Cell Function

por Neuman, Joshua C., Schaid, Michael D., Brill, Allison L., Fenske, Rachel J., Kibbe, Carly R., Fontaine, Danielle A., Sdao, Sophia M., Brar, Harpreet K., Connors, Kelsey M., Wienkes, Haley N., Eliceiri, Kevin W., Merrins, Matthew J., Davis, Dawn B., Kimple, Michelle E.
Publicado 2017

Reduced synchroneity of intra-islet Ca(2+) oscillations in vivo in Robo-deficient β cells

por Adams, Melissa T, Dwulet, JaeAnn M, Briggs, Jennifer K, Reissaus, Christopher A, Jin, Erli, Szulczewski, Joseph M, Lyman, Melissa R, Sdao, Sophia M, Kravets, Vira, Nimkulrat, Sutichot D, Ponik, Suzanne M, Merrins, Matthew J, Mirmira, Raghavendra G, Linnemann, Amelia K, Benninger, Richard KP, Blum, Barak
Publicado 2021