Regulatory Roles of PINK1-Parkin and AMPK in Ubiquitin-Dependent Skeletal Muscle Mitophagy

por Seabright, Alex P., Lai, Yu-Chiang
Publicado 2020

No effect of five days of bed rest or short‐term resistance exercise prehabilitation on markers of skeletal muscle mitochondrial content and dynamics in older adults

por Marshall, Ryan N., Smeuninx, Benoit, Seabright, Alex P., Morgan, Paul T., Atherton, Philip J., Philp, Andrew, Breen, Leigh
Publicado 2022

Acute resistance exercise training does not augment mitochondrial remodelling in master athletes or untrained older adults

por Marshall, Ryan Neil, McKendry, James, Smeuninx, Benoit, Seabright, Alex Peter, Morgan, Paul T., Greig, Carolyn, Breen, Leigh
Publicado 2023

Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis

por Webster, Justine M., Sagmeister, Michael S., Fenton, Chloe G., Seabright, Alex P., Lai, Yu-Chiang, Jones, Simon W., Filer, Andrew, Cooper, Mark S., Lavery, Gareth G., Raza, Karim, Langen, Ramon, Hardy, Rowan S.
Publicado 2021

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

por Seabright, Alex P., Fine, Nicholas H. F., Barlow, Jonathan P., Lord, Samuel O., Musa, Ibrahim, Gray, Alexander, Bryant, Jack A., Banzhaf, Manuel, Lavery, Gareth G., Hardie, D. Grahame, Hodson, David J., Philp, Andrew, Lai, Yu‐Chiang
Publicado 2020

The Effect of Ex Vivo Human Serum from Liver Disease Patients on Cellular Protein Synthesis and Growth

por Allen, Sophie L., Seabright, Alex P., Quinlan, Jonathan I., Dhaliwal, Amritpal, Williams, Felicity R., Fine, Nicholas H. F., Hodson, David J., Armstrong, Matthew J., Elsharkaway, Ahmed M., Greig, Carolyn A., Lai, Yu-Chiang, Lord, Janet M., Lavery, Gareth G., Breen, Leigh
Publicado 2022

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

por Elhassan, Yasir S., Kluckova, Katarina, Fletcher, Rachel S., Schmidt, Mark S., Garten, Antje, Doig, Craig L., Cartwright, David M., Oakey, Lucy, Burley, Claire V., Jenkinson, Ned, Wilson, Martin, Lucas, Samuel J.E., Akerman, Ildem, Seabright, Alex, Lai, Yu-Chiang, Tennant, Daniel A., Nightingale, Peter, Wallis, Gareth A., Manolopoulos, Konstantinos N., Brenner, Charles, Philp, Andrew, Lavery, Gareth G.
Publicado 2019