Amino Acid Residue 217 in the Hemagglutinin Glycoprotein Is a Key Mediator of Avian Influenza H7N9 Virus Antigenicity

por Chang, Pengxiang, Sealy, Joshua E., Sadeyen, Jean-Remy, Iqbal, Munir
Publicado 2018

A Global Perspective on H9N2 Avian Influenza Virus

por Peacock, T(homas). P., James, Joe, Sealy, Joshua E., Iqbal, Munir
Publicado 2019

A ligation and restriction enzyme independent cloning technique: an alternative to conventional methods for cloning hard-to-clone gene segments in the influenza reverse genetics sy...

por Bhat, Sushant, Bialy, Dagmara, Sealy, Joshua E., Sadeyen, Jean-Remy, Chang, Pengxiang, Iqbal, Munir
Publicado 2020

Genetic Determinants of Receptor-Binding Preference and Zoonotic Potential of H9N2 Avian Influenza Viruses

por Peacock, Thomas P., Sealy, Joshua E., Harvey, William T., Benton, Donald J., Reeve, Richard, Iqbal, Munir
Publicado 2021

Application of HDR-CRISPR/Cas9 and Erythrocyte Binding for Rapid Generation of Recombinant Turkey Herpesvirus-Vectored Avian Influenza Virus Vaccines

por Chang, Pengxiang, Ameen, Faisal, Sealy, Joshua E., Sadeyen, Jean-Remy, Bhat, Sushant, Li, Yongqing, Iqbal, Munir
Publicado 2019

The Evolution, Spread and Global Threat of H6Nx Avian Influenza Viruses

por Everest, Holly, Hill, Sarah C., Daines, Rebecca, Sealy, Joshua E., James, Joe, Hansen, Rowena, Iqbal, Munir
Publicado 2020

Immune Escape Adaptive Mutations in the H7N9 Avian Influenza Hemagglutinin Protein Increase Virus Replication Fitness and Decrease Pandemic Potential

por Chang, Pengxiang, Sealy, Joshua E., Sadeyen, Jean-Remy, Bhat, Sushant, Lukosaityte, Deimante, Sun, Yipeng, Iqbal, Munir
Publicado 2020

Engineered Recombinant Single Chain Variable Fragment of Monoclonal Antibody Provides Protection to Chickens Infected with H9N2 Avian Influenza

por Lukosaityte, Deimante, Sadeyen, Jean-Remy, Shrestha, Angita, Sealy, Joshua E., Bhat, Sushant, Chang, Pengxiang, Digard, Paul, Iqbal, Munir
Publicado 2020

Adsorptive mutation and N-linked glycosylation modulate influenza virus antigenicity and fitness

por Sealy, Joshua E., Peacock, Thomas P., Sadeyen, Jean-Remy, Chang, Pengxiang, Everest, Holly J., Bhat, Sushant, Iqbal, Munir
Publicado 2020

Amino acid substitutions in the H5N1 avian influenza haemagglutinin alter pH of fusion and receptor binding to promote a highly pathogenic phenotype in chickens

por Sealy, Joshua E., Howard, Wendy A., Molesti, Eleonora, Iqbal, Munir, Temperton, Nigel J., Banks, Jill, Slomka, Marek J., Barclay, Wendy S., Long, Jason S.
Publicado 2021

Antiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Infected Cell

por Xu, Jian, Li, Xiaoyang, Jiang, Bo, Feng, Xiaoyu, Wu, Jing, Cai, Yunhong, Zhang, Xixi, Huang, Xiufen, Sealy, Joshua E., Iqbal, Munir, Li, Yongqing
Publicado 2018

Contribution of Segment 3 to the Acquisition of Virulence in Contemporary H9N2 Avian Influenza Viruses

por Clements, Anabel L., Sealy, Joshua E., Peacock, Thomas P., Sadeyen, Jean-Remy, Hussain, Saira, Lycett, Samantha J., Shelton, Holly, Digard, Paul, Iqbal, Munir
Publicado 2020

PA-X is an avian virulence factor in H9N2 avian influenza virus

por Clements, Anabel L., Peacock, Thomas P., Sealy, Joshua E., Lee, Hui Min, Hussain, Saira, Sadeyen, Jean-Remy, Shelton, Holly, Digard, Paul, Iqbal, Munir
Publicado 2021

A DNA aptamer efficiently inhibits the infectivity of Bovine herpesvirus 1 by blocking viral entry

por Xu, Jian, Zhang, Xixi, Zhou, Shuanghai, Shen, Junjun, Yang, Dawei, Wu, Jing, Li, Xiaoyang, Li, Meiling, Huang, Xiufen, Sealy, Joshua E., Iqbal, Munir, Li, Yongqing
Publicado 2017

Poultry trading behaviours in Vietnamese live bird markets as risk factors for avian influenza infection in chickens

por Sealy, Joshua E., Fournie, Guillaume, Trang, Pham Hong, Dang, Nguyen Hoang, Sadeyen, Jean‐Remy, Thanh, To Long, van Doorn, H. Rogier, Bryant, Juliet E., Iqbal, Munir
Publicado 2019

The RNA helicase DDX5 promotes viral infection via regulating N(6)-methyladenosine levels on the DHX58 and NFκB transcripts to dampen antiviral innate immunity

por Xu, Jian, Cai, Yunhong, Ma, ZhenBang, Jiang, Bo, Liu, Wenxiao, Cheng, Jing, Guo, Nannan, Wang, Zishu, Sealy, Joshua E., Song, Cuiping, Wang, Xiaojia, Li, Yongqing
Publicado 2021

Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus

por Chang, Pengxiang, Lukosaityte, Deimante, Sealy, Joshua E., Rijal, Pramila, Sadeyen, Jean-Remy, Bhat, Sushant, Crossley, Sylvia, Daines, Rebecca, Huang, Kuan-Yin A., Townsend, Alain R., Iqbal, Munir
Publicado 2022

Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristic...

por Peacock, Thomas P., Benton, Donald J., James, Joe, Sadeyen, Jean-Remy, Chang, Pengxiang, Sealy, Joshua E., Bryant, Juliet E., Martin, Stephen R., Shelton, Holly, Barclay, Wendy S., Iqbal, Munir
Publicado 2017

Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion

por Peacock, Thomas P, Benton, Donald J, Sadeyen, Jean-Remy, Chang, Pengxiang, Sealy, Joshua E, Bryant, Juliet E, Martin, Stephen R, Shelton, Holly, McCauley, John W, Barclay, Wendy S, Iqbal, Munir
Publicado 2017

Fc-Mediated Functions of Porcine IgG Subclasses

por Paudyal, Basudev, Mwangi, William, Rijal, Pramila, Schwartz, John C., Noble, Alistair, Shaw, Andrew, Sealy, Joshua E., Bonnet-Di Placido, Marie, Graham, Simon P., Townsend, Alain, Hammond, John A., Tchilian, Elma
Publicado 2022