CD40 ligand induced cytotoxicity in carcinoma cells is enhanced by inhibition of metalloproteinase cleavage and delivery via a conditionally-replicating adenovirus

por Elmetwali, Taha, Searle, Peter F, McNeish, Iain, Young, Lawrence S, Palmer, Daniel H
Publicado 2010

The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP (+) provide glimpses of its catalytic mechanism

por White, Scott A., Christofferson, Andrew J., Grainger, Alastair I., Day, Martin A., Jarrom, David, Graziano, Antonio E., Searle, Peter F., Hyde, Eva I.
Publicado 2022

Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954

por Day, Martin A., Christofferson, Andrew J., Anderson, J. L. Ross, Vass, Simon O., Evans, Adam, Searle, Peter F., White, Scott A., Hyde, Eva I.
Publicado 2023

The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN

por Day, Martin A., Jarrom, David, Christofferson, Andrew J., Graziano, Antonio E., Anderson, J. L. Ross, Searle, Peter F., Hyde, Eva I., White, Scott A.
Publicado 2021