The who, where and how of fusobacteria and colon cancer

por Sears, Cynthia L
Publicado 2018

Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development

por Allen, Jawara, Sears, Cynthia L.
Publicado 2019

Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapy

por Drewes, Julia L, Housseau, Franck, Sears, Cynthia L
Publicado 2016

Clostridium difficile Infection in Pediatric Inflammatory Bowel Disease

por Hourigan, Suchitra K., Sears, Cynthia L., Oliva-Hemker, Maria
Publicado 2015

Impact of the microbiome on checkpoint inhibitor treatment in patients with non-small cell lung cancer and melanoma

por Shaikh, Fyza Y., Gills, Joell J., Sears, Cynthia L.
Publicado 2019

Next-generation sequencing: insights to advance clinical investigations of the microbiome

por Wensel, Caroline R., Pluznick, Jennifer L., Salzberg, Steven L., Sears, Cynthia L.
Publicado 2022

Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation

por Fu, Kai, Sun, Xin, Wier, Eric M, Hodgson, Andrea, Liu, Yue, Sears, Cynthia L, Wan, Fengyi
Publicado 2016

Diet-Related and Gut-Derived Metabolites and Health Outcomes: A Scoping Review

por Jia, Yuanxi, Yang, Xuhao, Wilson, Lisa M., Mueller, Noel T., Sears, Cynthia L., Treisman, Glenn J., Robinson, Karen A.
Publicado 2022

Gut colonization with an obesity-associated enteropathogenic microbe modulates the premetastatic niches to promote breast cancer lung and liver metastasis

por Parida, Sheetal, Siddharth, Sumit, Gatla, Himavanth R., Wu, Shaoguang, Wang, Guannan, Gabrielson, Kathleen, Sears, Cynthia L., Ladle, Brian H., Sharma, Dipali
Publicado 2023

Drug Discovery and Repurposing Inhibits a Major Gut Pathogen-Derived Oncogenic Toxin

por Metz, Paul, Tjan, Martijn J. H., Wu, Shaoguang, Pervaiz, Mehrosh, Hermans, Susanne, Shettigar, Aishwarya, Sears, Cynthia L., Ritschel, Tina, Dutilh, Bas E., Boleij, Annemarie
Publicado 2019

1001. Chronic Colonization with Toxigenic Clostridioides difficile Strains Drives Colonic Tumorigenesis in Mice

por Drewes, Julia L, Chen, Jie, Knippel, Reece, Markham, Nicholas, Domingue, Jada, Chan, June, McMann, Madison, Stevens, Courtney, Tam, Ada J, White, James, Mohammad, Fuad, Wu, Xinqun, Wu, Shaoguang, Simner, Patricia J, Carroll, Karen C, Carroll, Karen C, Ding, Hua, Shrubsole, Martha, Housseau, Franck, Lau, Ken, Coffey, Robert, Sears, Cynthia L, Sears, Cynthia L
Publicado 2021

Fecal Transplant in Children With Clostridioides difficile Gives Sustained Reduction in Antimicrobial Resistance and Potential Pathogen Burden

por Hourigan, Suchitra K, Ahn, Michelle, Gibson, Keylie M, Pérez-Losada, Marcos, Felix, Grace, Weidner, Melissa, Leibowitz, Ian, Niederhuber, John E, Sears, Cynthia L, Crandall, Keith A, Oliva-Hemker, Maria
Publicado 2019

Clinically adaptable polymer enables simultaneous spatial analysis of colonic tissues and biofilms

por Macedonia, Mary C., Drewes, Julia L., Markham, Nicholas O., Simmons, Alan J., Roland, Joseph T., Vega, Paige N., Scurrah, Cherie’ R., Coffey, Robert J., Shrubsole, Martha J., Sears, Cynthia L., Lau, Ken S.
Publicado 2020

Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Ge...

por Allen, Jawara, Rosendahl Huber, Axel, Pleguezuelos-Manzano, Cayetano, Puschhof, Jens, Wu, Shaoguang, Wu, Xinqun, Boot, Charelle, Saftien, Aurelia, O’Hagan, Heather M., Wang, Hao, van Boxtel, Ruben, Clevers, Hans, Sears, Cynthia L.
Publicado 2022

Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer

por Tomkovich, Sarah, Gharaibeh, Raad Z., Dejea, Christine M., Pope, Jillian L., Jiang, Jinmai, Winglee, Kathryn, Gauthier, Josee, Newsome, Rachel C., Yang, Ye, Fodor, Anthony A., Schmittgen, Thomas D., Sears, Cynthia L., Jobin, Christian
Publicado 2020

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

por Boleij, Annemarie, Fathi, Payam, Dalton, William, Park, Ben, Wu, Xinqun, Huso, David, Allen, Jawara, Besharati, Sepideh, Anders, Robert A., Housseau, Franck, Mackenzie, Amanda E., Jenkins, Laura, Milligan, Graeme., Wu, Shaoguang, Sears, Cynthia L.
Publicado 2021

Next-generation sequencing in neuropathologic diagnosis of infections of the nervous system

por Salzberg, Steven L., Breitwieser, Florian P., Kumar, Anupama, Hao, Haiping, Burger, Peter, Rodriguez, Fausto J., Lim, Michael, Quiñones-Hinojosa, Alfredo, Gallia, Gary L., Tornheim, Jeffrey A., Melia, Michael T., Sears, Cynthia L., Pardo, Carlos A.
Publicado 2016

The Myeloid Immune Signature of Enterotoxigenic Bacteroides Fragilis-Induced Murine Colon Tumorigenesis

por Orberg, Erik Thiele, Fan, Hongni, Tam, Ada J., Dejea, Christine M., Destefano-Shields, Christina E., Wu, Shaoguang, Chung, Liam, Finard, Benjamin B., Wu, Xinqun, Fathi, Payam, Ganguly, Sudipto, Fu, Juan, Pardoll, Drew M., Sears, Cynthia L., Housseau, Franck
Publicado 2016

Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A

por Chan, June L., Wu, Shaoguang, Geis, Abby L., Chan, Gabrielle V., Gomes, Talles A.M., Beck, Sarah E., Wu, Xinqun, Fan, Hongni, Tam, Ada J., Chung, Liam, Ding, Hua, Wang, Hao, Pardoll, Drew M., Housseau, Franck, Sears, Cynthia L.
Publicado 2018

A Central Role for Lipocalin-2 in the Adaptation to Short-Bowel Syndrome Through Down-Regulation of IL22 in Mice

por Zhang, Ailan, Sodhi, Chhinder P., Wang, Menghan, Shores, Darla R., Fulton, William, Prindle, Thomas, Brosten, Serena, O’Hare, Elizabeth, Lau, Alexander, Ding, Hua, Jia, Hongpeng, Lu, Peng, White, James R., Hui, Justin, Sears, Cynthia L., Hackam, David J., Alaish, Samuel M.
Publicado 2020