Untargeted Metabolomics of Slc13a5 Deficiency Reveal Critical Liver–Brain Axis for Lipid Homeostasis

por Milosavljevic, Sofia, Glinton, Kevin E., Li, Xiqi, Medeiros, Cláudia, Gillespie, Patrick, Seavitt, John R., Graham, Brett H., Elsea, Sarah H.
Publicado 2022

Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis

por Zhang, Jiangwen, Jackson, Audrey F., Naito, Taku, Dose, Marei, Seavitt, John, Liu, Feifei, Heller, Elizabeth J., Kashiwagi, Mariko, Yoshida, Toshimi, Gounari, Fotini, Petrie, Howard T., Georgopoulos, Katia
Publicado 2011

Three-dimensional microCT imaging of mouse development from early post-implantation to early postnatal stages

por Hsu, Chih-Wei, Wong, Leeyean, Rasmussen, Tara L., Kalaga, Sowmya, McElwee, Melissa L., Keith, Lance C., Bohat, Ritu, Seavitt, John R., Beaudet, Arthur L., Dickinson, Mary E.
Publicado 2016

Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction

por Hayakawa, Morisada, Hayakawa, Hiroko, Petrova, Tsvetana, Ritprajak, Patcharee, Sutavani, Ruhcha V., Jiménez-Andrade, Guillermina Yanek, Sano, Yasuyo, Choo, Min-Kyung, Seavitt, John, Venigalla, Ram K. C., Otsu, Kinya, Georgopoulos, Katia, Arthur, J. Simon C., Park, Jin Mo
Publicado 2017

Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles

por Lanza, Denise G., Gaspero, Angelina, Lorenzo, Isabel, Liao, Lan, Zheng, Ping, Wang, Ying, Deng, Yu, Cheng, Chonghui, Zhang, Chuansheng, Seavitt, John R., DeMayo, Francesco J., Xu, Jianming, Dickinson, Mary E., Beaudet, Arthur L., Heaney, Jason D.
Publicado 2018

Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance

por Stroup, Bridget M., Li, Xiaohui, Ho, Sara, Zhouyao, Haonan, Chen, Yuqing, Ani, Safa, Dawson, Brian, Jin, Zixue, Marom, Ronit, Jiang, Ming-Ming, Lorenzo, Isabel, Rosen, Daniel, Lanza, Denise, Aceves, Nathalie, Koh, Sara, Seavitt, John R., Heaney, Jason D., Lee, Brendan, Burrage, Lindsay C.
Publicado 2023

Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity

por Peterson, Kevin A., Khalouei, Sam, Hanafi, Nour, Wood, Joshua A., Lanza, Denise G., Lintott, Lauri G., Willis, Brandon J., Seavitt, John R., Braun, Robert E., Dickinson, Mary E., White, Jacqueline K., Lloyd, K. C. Kent, Heaney, Jason D., Murray, Stephen A., Ramani, Arun, Nutter, Lauryl M. J.
Publicado 2023

The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities

por Herbert, Eleanor, Stewart, Michelle, Hutchison, Marie, Flenniken, Ann M., Qu, Dawei, Nutter, Lauryl M. J., McKerlie, Colin, Hobson, Liane, Kick, Brenda, Lyons, Bonnie, Wiegand, Jean-Paul, Doty, Rosalinda, Aguilar-Pimentel, Juan Antonio, Hrabe de Angelis, Martin, Dickinson, Mary, Seavitt, John, White, Jacqueline K., Scudamore, Cheryl L., Wells, Sara
Publicado 2020

The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation

por Muñoz-Fuentes, Violeta, Cacheiro, Pilar, Meehan, Terrence F., Aguilar-Pimentel, Juan Antonio, Brown, Steve D. M., Flenniken, Ann M., Flicek, Paul, Galli, Antonella, Mashhadi, Hamed Haseli, Hrabě de Angelis, Martin, Kim, Jong Kyoung, Lloyd, K. C. Kent, McKerlie, Colin, Morgan, Hugh, Murray, Stephen A., Nutter, Lauryl M. J., Reilly, Patrick T., Seavitt, John R., Seong, Je Kyung, Simon, Michelle, Wardle-Jones, Hannah, Mallon, Ann-Marie, Smedley, Damian, Parkinson, Helen E.
Publicado 2018

Prevalence of sexual dimorphism in mammalian phenotypic traits

por Karp, Natasha A., Mason, Jeremy, Beaudet, Arthur L., Benjamini, Yoav, Bower, Lynette, Braun, Robert E., Brown, Steve D.M., Chesler, Elissa J., Dickinson, Mary E., Flenniken, Ann M., Fuchs, Helmut, Angelis, Martin Hrabe de, Gao, Xiang, Guo, Shiying, Greenaway, Simon, Heller, Ruth, Herault, Yann, Justice, Monica J., Kurbatova, Natalja, Lelliott, Christopher J., Lloyd, K.C. Kent, Mallon, Ann-Marie, Mank, Judith E., Masuya, Hiroshi, McKerlie, Colin, Meehan, Terrence F., Mott, Richard F., Murray, Stephen A., Parkinson, Helen, Ramirez-Solis, Ramiro, Santos, Luis, Seavitt, John R., Smedley, Damian, Sorg, Tania, Speak, Anneliese O., Steel, Karen P., Svenson, Karen L., Wakana, Shigeharu, West, David, Wells, Sara, Westerberg, Henrik, Yaacoby, Shay, White, Jacqueline K.
Publicado 2017

Human and mouse essentiality screens as a resource for disease gene discovery

por Cacheiro, Pilar, Muñoz-Fuentes, Violeta, Murray, Stephen A., Dickinson, Mary E., Bucan, Maja, Nutter, Lauryl M. J., Peterson, Kevin A., Haselimashhadi, Hamed, Flenniken, Ann M., Morgan, Hugh, Westerberg, Henrik, Konopka, Tomasz, Hsu, Chih-Wei, Christiansen, Audrey, Lanza, Denise G., Beaudet, Arthur L., Heaney, Jason D., Fuchs, Helmut, Gailus-Durner, Valerie, Sorg, Tania, Prochazka, Jan, Novosadova, Vendula, Lelliott, Christopher J., Wardle-Jones, Hannah, Wells, Sara, Teboul, Lydia, Cater, Heather, Stewart, Michelle, Hough, Tertius, Wurst, Wolfgang, Sedlacek, Radislav, Adams, David J., Seavitt, John R., Tocchini-Valentini, Glauco, Mammano, Fabio, Braun, Robert E., McKerlie, Colin, Herault, Yann, de Angelis, Martin Hrabě, Mallon, Ann-Marie, Lloyd, K. C.  Kent, Brown, Steve D. M., Parkinson, Helen, Meehan, Terrence F., Smedley, Damian
Publicado 2020

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

por Bowl, Michael R., Simon, Michelle M., Ingham, Neil J., Greenaway, Simon, Santos, Luis, Cater, Heather, Taylor, Sarah, Mason, Jeremy, Kurbatova, Natalja, Pearson, Selina, Bower, Lynette R., Clary, Dave A., Meziane, Hamid, Reilly, Patrick, Minowa, Osamu, Kelsey, Lois, Tocchini-Valentini, Glauco P., Gao, Xiang, Bradley, Allan, Skarnes, William C., Moore, Mark, Beaudet, Arthur L., Justice, Monica J., Seavitt, John, Dickinson, Mary E., Wurst, Wolfgang, de Angelis, Martin Hrabe, Herault, Yann, Wakana, Shigeharu, Nutter, Lauryl M. J., Flenniken, Ann M., McKerlie, Colin, Murray, Stephen A., Svenson, Karen L., Braun, Robert E., West, David B., Lloyd, K. C. Kent, Adams, David J., White, Jacqui, Karp, Natasha, Flicek, Paul, Smedley, Damian, Meehan, Terrence F., Parkinson, Helen E., Teboul, Lydia M., Wells, Sara, Steel, Karen P., Mallon, Ann-Marie, Brown, Steve D. M.
Publicado 2017

Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen

por Wotton, Janine M., Peterson, Emma, Flenniken, Ann M., Bains, Rasneer S., Veeraragavan, Surabi, Bower, Lynette R., Bubier, Jason A., Parisien, Marc, Bezginov, Alexandr, Haselimashhadi, Hamed, Mason, Jeremy, Moore, Michayla A., Stewart, Michelle E., Clary, Dave A., Delbarre, Daniel J., Anderson, Laura C., D'Souza, Abigail, Goodwin, Leslie O., Harrison, Mark E., Huang, Ziyue, Mckay, Matthew, Qu, Dawei, Santos, Luis, Srinivasan, Subhiksha, Urban, Rachel, Vukobradovic, Igor, Ward, Christopher S., Willett, Amelia M., Braun, Robert E., Brown, Steve D.M., Dickinson, Mary E., Heaney, Jason D., Kumar, Vivek, Lloyd, K.C. Kent, Mallon, Ann-Marie, McKerlie, Colin, Murray, Stephen A., Nutter, Lauryl M.J., Parkinson, Helen, Seavitt, John R., Wells, Sara, Samaco, Rodney C., Chesler, Elissa J., Smedley, Damian, Diatchenko, Luda, Baumbauer, Kyle M., Young, Erin E., Bonin, Robert P., Mandillo, Silvia, White, Jacqueline K.
Publicado 2022

Disease Model Discovery from 3,328 Gene Knockouts by The International Mouse Phenotyping Consortium

por Meehan, Terrence F., Conte, Nathalie, West, David B., Jacobsen, Julius O., Mason, Jeremy, Warren, Jonathan, Chen, Chao-Kung, Tudose, Ilinca, Relac, Mike, Matthews, Peter, Karp, Natasha, Santos, Luis, Fiegel, Tanja, Ring, Natalie, Westerberg, Henrik, Greenaway, Simon, Sneddon, Duncan, Morgan, Hugh, Codner, Gemma F, Stewart, Michelle E, Brown, James, Horner, Neil, Haendel, Melissa, Washington, Nicole, Mungall, Christopher J., Reynolds, Corey L, Gallegos, Juan, Gailus-Durner, Valerie, Sorg, Tania, Pavlovic, Guillaume, Bower, Lynette R, Moore, Mark, Morse, Iva, Gao, Xiang, Tocchini-Valentini, Glauco P, Obata, Yuichi, Cho, Soo Young, Seong, Je Kyung, Seavitt, John, Beaudet, Arthur L., Dickinson, Mary E., Herault, Yann, Wurst, Wolfgang, de Angelis, Martin Hrabe, Lloyd, K.C. Kent, Flenniken, Ann M, Nutter, Lauryl MJ, Newbigging, Susan, McKerlie, Colin, Justice, Monica J., Murray, Stephen A., Svenson, Karen L., Braun, Robert E., White, Jacqueline K., Bradley, Allan, Flicek, Paul, Wells, Sara, Skarnes, William C., Adams, David J., Parkinson, Helen, Mallon, Ann-Marie, Brown, Steve D.M., Smedley, Damian
Publicado 2017

Soft windowing application to improve analysis of high-throughput phenotyping data

por Haselimashhadi, Hamed, Mason, Jeremy C, Munoz-Fuentes, Violeta, López-Gómez, Federico, Babalola, Kolawole, Acar, Elif F, Kumar, Vivek, White, Jacqui, Flenniken, Ann M, King, Ruairidh, Straiton, Ewan, Seavitt, John Richard, Gaspero, Angelina, Garza, Arturo, Christianson, Audrey E, Hsu, Chih-Wei, Reynolds, Corey L, Lanza, Denise G, Lorenzo, Isabel, Green, Jennie R, Gallegos, Juan J, Bohat, Ritu, Samaco, Rodney C, Veeraragavan, Surabi, Kim, Jong Kyoung, Miller, Gregor, Fuchs, Helmult, Garrett, Lillian, Becker, Lore, Kang, Yeon Kyung, Clary, David, Cho, Soo Young, Tamura, Masaru, Tanaka, Nobuhiko, Soo, Kyung Dong, Bezginov, Alexandr, About, Ghina Bou, Champy, Marie-France, Vasseur, Laurent, Leblanc, Sophie, Meziane, Hamid, Selloum, Mohammed, Reilly, Patrick T, Spielmann, Nadine, Maier, Holger, Gailus-Durner, Valerie, Sorg, Tania, Hiroshi, Masuya, Yuichi, Obata, Heaney, Jason D, Dickinson, Mary E, Wolfgang, Wurst, Tocchini-Valentini, Glauco P, Lloyd, Kevin C Kent, McKerlie, Colin, Seong, Je Kyung, Yann, Herault, de Angelis, Martin Hrabé, Brown, Steve D M, Smedley, Damian, Flicek, Paul, Mallon, Ann-Marie, Parkinson, Helen, Meehan, Terrence F
Publicado 2020

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

por Swan, Anna L., Schütt, Christine, Rozman, Jan, del Mar Muñiz Moreno, Maria, Brandmaier, Stefan, Simon, Michelle, Leuchtenberger, Stefanie, Griffiths, Mark, Brommage, Robert, Keskivali-Bond, Piia, Grallert, Harald, Werner, Thomas, Teperino, Raffaele, Becker, Lore, Miller, Gregor, Moshiri, Ala, Seavitt, John R., Cissell, Derek D., Meehan, Terrence F., Acar, Elif F., Lelliott, Christopher J., Flenniken, Ann M., Champy, Marie-France, Sorg, Tania, Ayadi, Abdel, Braun, Robert E., Cater, Heather, Dickinson, Mary E., Flicek, Paul, Gallegos, Juan, Ghirardello, Elena J., Heaney, Jason D., Jacquot, Sylvie, Lally, Connor, Logan, John G., Teboul, Lydia, Mason, Jeremy, Spielmann, Nadine, McKerlie, Colin, Murray, Stephen A., Nutter, Lauryl M. J., Odfalk, Kristian F., Parkinson, Helen, Prochazka, Jan, Reynolds, Corey L., Selloum, Mohammed, Spoutil, Frantisek, Svenson, Karen L., Vales, Taylor S., Wells, Sara E., White, Jacqueline K., Sedlacek, Radislav, Wurst, Wolfgang, Lloyd, K. C. Kent, Croucher, Peter I., Fuchs, Helmut, Williams, Graham R., Bassett, J. H. Duncan, Gailus-Durner, Valerie, Herault, Yann, Mallon, Ann-Marie, Brown, Steve D. M., Mayer-Kuckuk, Philipp, Hrabe de Angelis, Martin
Publicado 2020

Identification of genes required for eye development by high-throughput screening of mouse knockouts

por Moore, Bret A., Leonard, Brian C., Sebbag, Lionel, Edwards, Sydney G., Cooper, Ann, Imai, Denise M., Straiton, Ewan, Santos, Luis, Reilly, Christopher, Griffey, Stephen M., Bower, Lynette, Clary, David, Mason, Jeremy, Roux, Michel J., Meziane, Hamid, Herault, Yann, McKerlie, Colin, Flenniken, Ann M., Nutter, Lauryl M. J., Berberovic, Zorana, Owen, Celeste, Newbigging, Susan, Adissu, Hibret, Eskandarian, Mohammed, Hsu, Chih-Wei, Kalaga, Sowmya, Udensi, Uchechukwu, Asomugha, Chinwe, Bohat, Ritu, Gallegos, Juan J., Seavitt, John R., Heaney, Jason D., Beaudet, Arthur L., Dickinson, Mary E., Justice, Monica J., Philip, Vivek, Kumar, Vivek, Svenson, Karen L., Braun, Robert E., Wells, Sara, Cater, Heather, Stewart, Michelle, Clementson-Mobbs, Sharon, Joynson, Russell, Gao, Xiang, Suzuki, Tomohiro, Wakana, Shigeharu, Smedley, Damian, Seong, J. K, Tocchini-Valentini, Glauco, Moore, Mark, Fletcher, Colin, Karp, Natasha, Ramirez-Solis, Ramiro, White, Jacqueline K., de Angelis, Martin Hrabe, Wurst, Wolfgang, Thomasy, Sara M., Flicek, Paul, Parkinson, Helen, Brown, Steve D. M., Meehan, Terrence F., Nishina, Patsy M., Murray, Stephen A., Krebs, Mark P., Mallon, Ann-Marie, Lloyd, K. C. Kent, Murphy, Christopher J., Moshiri, Ala
Publicado 2018

Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts

por Moore, Bret A., Leonard, Brian C., Sebbag, Lionel, Edwards, Sydney G., Cooper, Ann, Imai, Denise M., Straiton, Ewan, Santos, Luis, Reilly, Christopher, Griffey, Stephen M., Bower, Lynette, Clary, David, Mason, Jeremy, Roux, Michel J., Meziane, Hamid, Herault, Yann, McKerlie, Colin, Flenniken, Ann M., Nutter, Lauryl M. J., Berberovic, Zorana, Owen, Celeste, Newbigging, Susan, Adissu, Hibret, Eskandarian, Mohammed, Hsu, Chih-Wei, Kalaga, Sowmya, Udensi, Uchechukwu, Asomugha, Chinwe, Bohat, Ritu, Gallegos, Juan J., Seavitt, John R., Heaney, Jason D., Beaudet, Arthur L., Dickinson, Mary E., Justice, Monica J., Philip, Vivek, Kumar, Vivek, Svenson, Karen L., Braun, Robert E., Wells, Sara, Cater, Heather, Stewart, Michelle, Clementson-Mobbs, Sharon, Joynson, Russell, Gao, Xiang, Suzuki, Tomohiro, Wakana, Shigeharu, Smedley, Damian, Seong, J. K., Tocchini-Valentini, Glauco, Moore, Mark, Fletcher, Colin, Karp, Natasha, Ramirez-Solis, Ramiro, White, Jacqueline K., de Angelis, Martin Hrabe, Wurst, Wolfgang, Thomasy, Sara M., Flicek, Paul, Parkinson, Helen, Brown, Steve D. M., Meehan, Terrence F., Nishina, Patsy M., Murray, Stephen A., Krebs, Mark P., Mallon, Ann-Marie, Kent Lloyd, K. C., Murphy, Christopher J., Moshiri, Ala
Publicado 2019

High-throughput discovery of novel developmental phenotypes

por Dickinson, Mary E., Flenniken, Ann M., Ji, Xiao, Teboul, Lydia, Wong, Michael D., White, Jacqueline K., Meehan, Terrence F., Weninger, Wolfgang J., Westerberg, Henrik, Adissu, Hibret, Baker, Candice N., Bower, Lynette, Brown, James M., Caddle, L. Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J., Denegre, James M., Doe, Brendan, Dolan, Mary E., Edie, Sarah M., Fuchs, Helmut, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R., Hsu, Chih-wei, Johnson, Sara J., Kalaga, Sowmya, Keith, Lance C., Lanoue, Louise, Lawson, Thomas N., Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L., Newbigging, Susan, Nutter, Lauryl M.J., Peterson, Kevin A., Ramirez-Solis, Ramiro, Rowland, Douglas J., Ryder, Edward, Samocha, Kaitlin E., Seavitt, John R., Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G, Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B., Wong, Leeyean, Yoshiki, Atsushi, MacArthur, Daniel G., Tocchini-Valentini, Glauco P., Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C., Justice, Monica J., Parkinson, Helen E., Moore, Mark, Wells, Sara, Braun, Robert E., Svenson, Karen L., de Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R. Mark, Brown, Steve D.M., Adams, David J., Lloyd, K.C. Kent, McKerlie, Colin, Beaudet, Arthur L., Bucan, Maja, Murray, Stephen A.
Publicado 2016