A Selection Fit Mechanism in BMP Receptor IA as a Possible Source for BMP Ligand-Receptor Promiscuity

por Harth, Stefan, Kotzsch, Alexander, Hu, Junli, Sebald, Walter, Mueller, Thomas D.
Publicado 2010

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

por Heinecke, Kai, Seher, Axel, Schmitz, Werner, Mueller, Thomas D, Sebald, Walter, Nickel, Joachim
Publicado 2009

A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor

por Kraich, Michael, Klein, Markus, Patiño, Edwin, Harrer, Henning, Nickel, Joachim, Sebald, Walter, Mueller, Thomas D
Publicado 2006

Biological activity of a genetically modified BMP-2 variant with inhibitory activity

por Klammert, Uwe, Nickel, Joachim, Würzler, Kristian, Klingelhöffer, Christoph, Sebald, Walter, Kübler, Alexander C, Reuther, Tobias
Publicado 2009

Binding between Crossveinless-2 and Chordin Von Willebrand Factor Type C Domains Promotes BMP Signaling by Blocking Chordin Activity

por Zhang, Jin-Li, Patterson, Lucy J., Qiu, Li-Yan, Graziussi, Daria, Sebald, Walter, Hammerschmidt, Matthias
Publicado 2010

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor

por Weber, Dionys, Kotzsch, Alexander, Nickel, Joachim, Harth, Stefan, Seher, Axel, Mueller, Uwe, Sebald, Walter, Mueller, Thomas D
Publicado 2007

Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitro

por Seher, Axel, Nickel, Joachim, Mueller, Thomas D., Kneitz, Susanne, Gebhardt, Susanne, ter Vehn, Tobias Meyer, Schlunck, Guenther, Sebald, Walter
Publicado 2011

Utilizing BMP-2 muteins for treatment of multiple myeloma

por Seher, Axel, Lagler, Charlotte, Stühmer, Thorsten, Müller-Richter, Urs Dietmar Achim, Kübler, Alexander Christian, Sebald, Walter, Müller, Thomas Dieter, Nickel, Joachim
Publicado 2017

GDF-5 can act as a context-dependent BMP-2 antagonist

por Klammert, Uwe, Mueller, Thomas D., Hellmann, Tina V., Wuerzler, Kristian K., Kotzsch, Alexander, Schliermann, Anna, Schmitz, Werner, Kuebler, Alexander C., Sebald, Walter, Nickel, Joachim
Publicado 2015

The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed

por Fiebig, Juliane E., Weidauer, Stella E., Qiu, Li-Yan, Bauer, Markus, Schmieder, Peter, Beerbaum, Monika, Zhang, Jin-Li, Oschkinat, Hartmut, Sebald, Walter, Mueller, Thomas D.
Publicado 2013

Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN

por Seemann, Petra, Brehm, Anja, König, Jana, Reissner, Carsten, Stricker, Sigmar, Kuss, Pia, Haupt, Julia, Renninger, Stephanie, Nickel, Joachim, Sebald, Walter, Groppe, Jay C., Plöger, Frank, Pohl, Jens, Schmidt-von Kegler, Mareen, Walther, Maria, Gassner, Ingmar, Rusu, Cristina, Janecke, Andreas R., Dathe, Katarina, Mundlos, Stefan
Publicado 2009