Cancer–Osteoblast Interaction Reduces Sost Expression in Osteoblasts and Up-Regulates lncRNA MALAT1 in Prostate Cancer

por Sebastian, Aimy, Hum, Nicholas R., Hudson, Bryan D., Loots, Gabriela G.
Publicado 2015

Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of GATA1 and STAG2 Mutations in Induced Pluripotent Stem Cells with Trisomy 21

por Barwe, Sonali P., Sebastian, Aimy, Sidhu, Ishnoor, Kolb, Edward Anders, Gopalakrishnapillai, Anilkumar
Publicado 2022

Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts

por Sebastian, Aimy, Hum, Nicholas R., Murugesh, Deepa K., Hatsell, Sarah, Economides, Aris N., Loots, Gabriela G.
Publicado 2017

Global molecular changes in a tibial compression induced ACL rupture model of post‐traumatic osteoarthritis

por Chang, Jiun C., Sebastian, Aimy, Murugesh, Deepa K., Hatsell, Sarah, Economides, Aris N., Christiansen, Blaine A., Loots, Gabriela G.
Publicado 2016

Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes

por Sebastian, Aimy, McCool, Jillian L., Hum, Nicholas R., Murugesh, Deepa K., Wilson, Stephen P., Christiansen, Blaine A., Loots, Gabriela G.
Publicado 2021

Preexisting Type 1 Diabetes Mellitus Blunts the Development of Posttraumatic Osteoarthritis

por Rios‐Arce, Naiomy D, Murugesh, Deepa K, Hum, Nicholas R, Sebastian, Aimy, Jbeily, Elias H, Christiansen, Blaine A, Loots, Gabriela G
Publicado 2022

Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression

por Sebastian, Aimy, Chang, Jiun C., Mendez, Melanie E., Murugesh, Deepa K., Hatsell, Sarah, Economides, Aris N., Christiansen, Blaine A., Loots, Gabriela G.
Publicado 2018

Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner()

por Collette, Nicole M., Yee, Cristal S., Murugesh, Deepa, Sebastian, Aimy, Taher, Leila, Gale, Nicholas W., Economides, Aris N., Harland, Richard M., Loots, Gabriela G.
Publicado 2013

Antibiotic Treatment Prior to Injury Improves Post-Traumatic Osteoarthritis Outcomes in Mice

por Mendez, Melanie E., Murugesh, Deepa K., Sebastian, Aimy, Hum, Nicholas R., McCloy, Summer A., Kuhn, Edward A., Christiansen, Blaine A., Loots, Gabriela G.
Publicado 2020

LPS‐Induced Inflammation Prior to Injury Exacerbates the Development of Post‐Traumatic Osteoarthritis in Mice

por Mendez, Melanie E, Sebastian, Aimy, Murugesh, Deepa K, Hum, Nicholas R, McCool, Jillian L, Hsia, Allison W, Christiansen, Blaine A, Loots, Gabriela G
Publicado 2020

MAVS mediates a protective immune response in the brain to Rift Valley fever virus

por Hum, Nicholas R., Bourguet, Feliza A., Sebastian, Aimy, Lam, Doris, Phillips, Ashlee M., Sanchez, Kristina R., Rasley, Amy, Loots, Gabriela G., Weilhammer, Dina R.
Publicado 2022

Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening

por Griffin, Katherine H., Thorpe, Steven W., Sebastian, Aimy, Hum, Nicholas R., Coonan, Thomas P., Sagheb, Isabel S., Loots, Gabriela G., Randall, R. Lor, Leach, J. Kent
Publicado 2023

SOST Inhibits Prostate Cancer Invasion

por Hudson, Bryan D., Hum, Nicholas R., Thomas, Cynthia B., Kohlgruber, Ayano, Sebastian, Aimy, Collette, Nicole M., Coleman, Matthew A., Christiansen, Blaine A., Loots, Gabriela G.
Publicado 2015

Methionine Adenosyltransferase 1a (MAT1A) Enhances Cell Survival During Chemotherapy Treatment and is Associated with Drug Resistance in Bladder Cancer PDX Mice

por Martin, Kelly A., Hum, Nicholas R., Sebastian, Aimy, He, Wei, Siddiqui, Salma, Ghosh, Paramita M., Pan, Chong-xian, de Vere White, Ralph, Loots, Gabriela G.
Publicado 2019

Global Gene Expression Analysis Identifies Age-Related Differences in Knee Joint Transcriptome during the Development of Post-Traumatic Osteoarthritis in Mice

por Sebastian, Aimy, Murugesh, Deepa K., Mendez, Melanie E., Hum, Nicholas R., Rios-Arce, Naiomy D., McCool, Jillian L., Christiansen, Blaine A., Loots, Gabriela G.
Publicado 2020

Single-Cell Transcriptomic Analysis of Tumor-Derived Fibroblasts and Normal Tissue-Resident Fibroblasts Reveals Fibroblast Heterogeneity in Breast Cancer

por Sebastian, Aimy, Hum, Nicholas R., Martin, Kelly A., Gilmore, Sean F., Peran, Ivana, Byers, Stephen W., Wheeler, Elizabeth K., Coleman, Matthew A., Loots, Gabriela G.
Publicado 2020

Dose-dependent consequences of sub-chronic fentanyl exposure on neuron and glial co-cultures

por Lam, Doris, Sebastian, Aimy, Bogguri, Chandrakumar, Hum, Nicholas R., Ladd, Alexander, Cadena, Jose, Valdez, Carlos A., Fischer, Nicholas O., Loots, Gabriela G., Enright, Heather A.
Publicado 2022

IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast Cancer

por Hum, Nicholas R., Sebastian, Aimy, Martin, Kelly A., Rios-Arce, Naiomy D., Gilmore, Sean F., Gravano, David M., Wheeler, Elizabeth K., Coleman, Matthew A., Loots, Gabriela G.
Publicado 2022

SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury

por Chang, Jiun C, Christiansen, Blaine A, Murugesh, Deepa K, Sebastian, Aimy, Hum, Nicholas R, Collette, Nicole M, Hatsell, Sarah, Economides, Aris N, Blanchette, Craig D, Loots, Gabriela G
Publicado 2018

Loss of Cadherin-11 in pancreatic ductal adenocarcinoma alters tumor-immune microenvironment

por Sebastian, Aimy, Martin, Kelly A., Peran, Ivana, Hum, Nicholas R., Leon, Nicole F., Amiri, Beheshta, Wilson, Stephen P., Coleman, Matthew A., Wheeler, Elizabeth K., Byers, Stephen W., Loots, Gabriela G.
Publicado 2023