Apatite phosphate doped by cobalt as hight efficient catalyst of multi-component synthesis of therapeutic spiropyrimidine compound

por Rhihil, Abdallah, Aichi, Youness, Zahouily, Mohamed, Sebti, Saïd, El Guendouzi, Mohamed
Publicado 2022

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities

por Patel, Ronil A., Liu, Yan, Wang, Binglin, Li, Rongshi, Sebti, Saïd M.
Publicado 2013

Novel mutant KRAS addiction signature predicts response to the combination of ERBB and MEK inhibitors in lung and pancreatic cancers

por Tyc, Katarzyna M., Kazi, Aslamuzzaman, Ranjan, Alok, Wang, Rui, Sebti, Said M.
Publicado 2023

Poly[(μ(3)-hydrogenphosphato)(4H-1,2,4-triazole-κN (1))zinc]

por Aitenneite, Hafid, El Bouari, Abdeslam, Sebti, Said, Saadi, Mohamed, El Ammari, Lahcen, Adil, Karim
Publicado 2012

δ-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis

por Husain, Kazim, Centeno, Barbara A, Coppola, Domenico, Trevino, Jose, Sebti, Said M, Malafa, Mokenge P
Publicado 2017

Lysophosphatidic Acid Acyltransferase Beta Regulates mTOR Signaling

por Blaskovich, Michelle A., Yendluri, Vimala, Lawrence, Harshani R., Lawrence, Nicholas J., Sebti, Saïd M., Springett, Gregory M.
Publicado 2013

Experimental Design-Based Response Surface Methodology Optimization for Synthesis of β-Mercapto Carbonyl Derivatives as Antimycobacterial Drugs Catalyzed by Calcium Pyrophosphate

por Abrouki, Younes, Anouzla, Abdelkader, Loukili, Hayat, Bennazha, Jamal, Lotfi, Rabiaâ, Rayadh, Ahmed, Bahlaoui, My Abdellah, Sebti, Saïd, Zakarya, Driss, Zahouily, Mohamed
Publicado 2014

Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104)

por Gajewski, Thomas F, Salama, April KS, Niedzwiecki, Donna, Johnson, Jeffrey, Linette, Gerald, Bucher, Cynthia, Blaskovich, Michelle A, Sebti, Said M, Haluska, Frank
Publicado 2012

Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation

por Yang, Hua, Lawrence, Harshani R., Kazi, Aslamuzzaman, Gevariya, Harsukh, Patel, Ronil, Luo, Yunting, Rix, Uwe, Schonbrunn, Ernst, Lawrence, Nicholas J., Sebti, Said M.
Publicado 2014

A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia

por Springett, Gregory M., Husain, Kazim, Neuger, Anthony, Centeno, Barbara, Chen, Dung-Tsa, Hutchinson, Tai Z., Lush, Richard M., Sebti, Saïd, Malafa, Mokenge P.
Publicado 2015

GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors

por Kazi, Aslamuzzaman, Xiang, Shengyan, Yang, Hua, Delitto, Daniel, Trevino, José, Jiang, Rays H. Y., Ayaz, Muhammad, Lawrence, Harshani R., Kennedy, Perry, Sebti, Saïd M.
Publicado 2018

Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIP(s)

por Francois, Rony A., Zhang, Anying, Husain, Kazim, Wang, Chen, Hutchinson, Sean, Kongnyuy, Michael, Batra, Surinder K., Coppola, Domenico, Sebti, Said M., Malafa, Mokenge P.
Publicado 2019

The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane

por Berndt, Norbert, Yang, Hua, Trinczek, Bernhard, Betzi, Stéphane, Zhang, Ziming, Wu, Bainan, Lawrence, Nicholas J., Pellecchia, Maurizio, Schönbrunn, Ernst, Cheng, Jin Q., Sebti, Saïd M.
Publicado 2010

Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-x(L) Binding to Bim

por Cheng, Chunwei, Liu, Yan, Balasis, Maria E., Simmons, Nicholas L., Li, Jerry, Song, Hao, Pan, Lili, Qin, Yong, Nicolaou, K. C., Sebti, Said M., Li, Rongshi
Publicado 2014

Vitamin E δ-Tocotrienol Induces p27(Kip1)-Dependent Cell-Cycle Arrest in Pancreatic Cancer Cells via an E2F-1-Dependent Mechanism

por Hodul, Pamela J., Dong, Yanbin, Husain, Kazim, Pimiento, Jose M., Chen, Jiandong, Zhang, Anying, Francois, Rony, Pledger, Warren J., Coppola, Domenico, Sebti, Said M., Chen, Dung-Tsa, Malafa, Mokenge P.
Publicado 2013

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim

por Cheng, Chunwei, Liu, Yan, Balasis, Maria E., Garner, Thomas P., Li, Jerry, Simmons, Nicholas L., Berndt, Norbert, Song, Hao, Pan, Lili, Qin, Yong, Nicolaou, K. C., Gavathiotis, Evripidis, Sebti, Said M., Li, Rongshi
Publicado 2014

PTEN counteracts FBXL2 to promote IP3R3– and Ca(2+)–mediated apoptosis limiting tumour growth

por Kuchay, Shafi, Giorgi, Carlotta, Simoneschi, Daniele, Pagan, julia, Missiroli, Sonia, Saraf, Anita, Florens, Laurence, Washburn, Michael P., Collazo-Lorduy, Ana, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Sebti, Said M., Pinton, Paolo, Pagano, Michele
Publicado 2017

Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation

por Mahajan, Kiran, Coppola, Domenico, Challa, Sridevi, Fang, Bin, Chen, Y. Ann, Zhu, Weiwei, Lopez, Alexis S., Koomen, John, Engelman, Robert W., Rivera, Charlene, Muraoka-Cook, Rebecca S., Cheng, Jin Q., Schönbrunn, Ernst, Sebti, Said M., Earp, H. Shelton, Mahajan, Nupam P.
Publicado 2010

Prostate Cancer Chemoprevention Targeting Men with High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) and Atypical Small Acinar Proliferation (ASAP): Model for Trial Design and...

por Kumar, Nagi, Crocker, Theresa, Smith, Tiffany, Connors, Shahnjayla, Pow-Sang, Julio, Spiess, Philippe E., Egan, Kathleen, Quinn, Gwen, Schell, Michael, Sebti, Said, Kazi, Aslam, Chuang, Tian, Salup, Raoul, Helal, Mohamed, Zagaja, Gregory, Trabulsi, Edouard, McLarty, Jerry, Fazili, Tajammul, Williams, Christopher R., Schreiber, Fred, Anderson, Kyle
Publicado 2012