Novel multi-objective affinity approach allows to identify pH-specific μ-opioid receptor agonists

por Secker, Christopher, Fackeldey, Konstantin, Weber, Marcus, Ray, Sourav, Gorgulla, Christoph, Schütte, Christof
Publicado 2023

LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells

por Trepte, Philipp, Kruse, Sabrina, Kostova, Simona, Hoffmann, Sheila, Buntru, Alexander, Tempelmeier, Anne, Secker, Christopher, Diez, Lisa, Schulz, Aline, Klockmeier, Konrad, Zenkner, Martina, Golusik, Sabrina, Rau, Kirstin, Schnoegl, Sigrid, Garner, Craig C, Wanker, Erich E
Publicado 2018

N‐methyl‐D‐aspartate receptor dysfunction by unmutated human antibodies against the NR1 subunit

por Wenke, Nina Kerstin, Kreye, Jakob, Andrzejak, Ewa, van Casteren, Adriana, Leubner, Jonas, Murgueitio, Manuela S., Reincke, S. Momsen, Secker, Christopher, Schmidl, Lars, Geis, Christian, Ackermann, Frauke, Nikolaus, Marc, Garner, Craig C., Wardemann, Hedda, Wolber, Gerhard, Prüss, Harald
Publicado 2019

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

por Trepte, Philipp, Secker, Christopher, Kostova, Simona, Maseko, Sibusiso B., Choi, Soon Gang, Blavier, Jeremy, Minia, Igor, Ramos, Eduardo Silva, Cassonnet, Patricia, Golusik, Sabrina, Zenkner, Martina, Beetz, Stephanie, Liebich, Mara J., Scharek, Nadine, Schütz, Anja, Sperling, Marcel, Lisurek, Michael, Wang, Yang, Spirohn, Kerstin, Hao, Tong, Calderwood, Michael A., Hill, David E., Landthaler, Markus, Olivet, Julien, Twizere, Jean-Claude, Vidal, Marc, Wanker, Erich E.
Publicado 2023

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

por Inak, Gizem, Rybak-Wolf, Agnieszka, Lisowski, Pawel, Pentimalli, Tancredi M., Jüttner, René, Glažar, Petar, Uppal, Karan, Bottani, Emanuela, Brunetti, Dario, Secker, Christopher, Zink, Annika, Meierhofer, David, Henke, Marie-Thérèse, Dey, Monishita, Ciptasari, Ummi, Mlody, Barbara, Hahn, Tobias, Berruezo-Llacuna, Maria, Karaiskos, Nikos, Di Virgilio, Michela, Mayr, Johannes A., Wortmann, Saskia B., Priller, Josef, Gotthardt, Michael, Jones, Dean P., Mayatepek, Ertan, Stenzel, Werner, Diecke, Sebastian, Kühn, Ralf, Wanker, Erich E., Rajewsky, Nikolaus, Schuelke, Markus, Prigione, Alessandro
Publicado 2021