IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3K(δ) inhibitor idelalisib

por Sandova, Veronika, Pavlasova, Gabriela Mladonicka, Seda, Vaclav, Cerna, Katerina Amruz, Sharma, Sonali, Palusova, Veronika, Brychtova, Yvona, Pospisilova, Sarka, Fernandes, Stacey M., Panovska, Anna, Doubek, Michael, Davids, Matthew S., Brown, Jennifer R., Mayer, Jiri, Mraz, Marek
Publicado 2021

Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells

por Boudny, Miroslav, Zemanova, Jana, Khirsariya, Prashant, Borsky, Marek, Verner, Jan, Cerna, Jana, Oltova, Alexandra, Seda, Vaclav, Mraz, Marek, Jaros, Josef, Jaskova, Zuzana, Spunarova, Michaela, Brychtova, Yvona, Soucek, Karel, Drapela, Stanislav, Kasparkova, Marie, Mayer, Jiri, Paruch, Kamil, Trbusek, Martin
Publicado 2019

S142: FOXO1-RICTOR AXIS INDUCES ADAPTIVE INCREASE IN AKT ACTIVITY DURING BCR INHIBITOR THERAPY IN CLL: IMPLICATIONS FOR COMBINATION THERAPY

por Ondrisova, Laura, Seda, Vaclav, Hoferkova, Eva, Chiodin, Giorgia, Hlavac, Krystof, Kostalova, Lenka, Filip, Daniel, Faria Zeni, Pedro, Panovska, Anna, Plevova, Karla, Pospisilova, Sarka, Simkovic, Martin, Vrbacky, Filip, Lysak, Daniel, Fernandes, Stacey M., Davids, Matthew S., Maiques-Diaz, Alba, Charalampopoulou, Stella, Martin-Subero, Jose I, Brown, Jennifer R, Doubek, Michael, Forconi, Francesco, Mayer, Jiri, Mraz, Marek
Publicado 2023