ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations

por Hajji, Khadija, Sedmík, Jiří, Cherian, Anna, Amoruso, Damiano, Keegan, Liam P., O'Connell, Mary A.
Publicado 2022

Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein

por Wiatrek, Dagmara M., Candela, Maria E., Sedmík, Jiří, Oppelt, Jan, Keegan, Liam P., O'Connell, Mary A.
Publicado 2019

Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids

por Barak, Martin, Fedorova, Veronika, Pospisilova, Veronika, Raska, Jan, Vochyanova, Simona, Sedmik, Jiri, Hribkova, Hana, Klimova, Hana, Vanova, Tereza, Bohaciakova, Dasa
Publicado 2022

Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration

por Fedorova, Veronika, Pospisilova, Veronika, Vanova, Tereza, Amruz Cerna, Katerina, Abaffy, Pavel, Sedmik, Jiri, Raska, Jan, Vochyanova, Simona, Matusova, Zuzana, Houserova, Jana, Valihrach, Lukas, Hodny, Zdenek, Bohaciakova, Dasa
Publicado 2023

Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy

por Maroofian, Reza, Sedmík, Jiří, Mazaheri, Neda, Scala, Marcello, Zaki, Maha S, Keegan, Liam P, Azizimalamiri, Reza, Issa, Mahmoud, Shariati, Gholamreza, Sedaghat, Alireza, Beetz, Christian, Bauer, Peter, Galehdari, Hamid, O’Connell, Mary A, Houlden, Henry
Publicado 2021

Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

por Nemergut, Michal, Marques, Sérgio M., Uhrik, Lukas, Vanova, Tereza, Nezvedova, Marketa, Gadara, Darshak Chandulal, Jha, Durga, Tulis, Jan, Novakova, Veronika, Planas-Iglesias, Joan, Kunka, Antonin, Legrand, Anthony, Hribkova, Hana, Pospisilova, Veronika, Sedmik, Jiri, Raska, Jan, Prokop, Zbynek, Damborsky, Jiri, Bohaciakova, Dasa, Spacil, Zdenek, Hernychova, Lenka, Bednar, David, Marek, Martin
Publicado 2023