ANTI-AGING COMPOUNDS METFORMIN AND THIOFLAVIN T CAN ACT ON GENETICALLY DIVERSE, PROTEOSTASIS-COMPROMISED STRAINS

por Driscoll, Monica, Onken, Brian, Xu, Yunpeng, Song, Yuhua, Achanta, Madhuri, Sedore, Christine, Phillips, Patrick, Lithgow, Gordon
Publicado 2022

ROBUST LONGEVITY EFFECTS OF NOVEL COMPOUNDS TESTED BY THE CAENORHABDITIS INTERVENTION TESTING PROGRAM

por Driscoll, Monica, Onken, Brian, Sedore, Christine, Coleman-Hulbert, Anna, Hall, David, Lithgow, Gordon, Phillips, Patrick, Montes, Viviana Perez
Publicado 2022

Caenorhabditis Intervention Testing Program: the creatine analog β-guanidinopropionic acid does not extend lifespan in nematodes

por Coleman-Hulbert, Anna L., Johnson, Erik, Sedore, Christine A., Banse, Stephen A., Guo, Max, Driscoll, Monica, Lithgow, Gordon J., Phillips, Patrick C.
Publicado 2020

Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes

por Coleman-Hulbert, Anna L., Johnson, Erik, Sedore, Christine A., Banse, Stephen A., Guo, Max, Driscoll, Monica, Lithgow, Gordon J., Phillips, Patrick C.
Publicado 2019

Caenorhabditis Intervention Testing Program: the herbicide diuron does not robustly extend lifespan in nematodes

por Osman, Hadley C, Sedore, Christine A, Jackson, E Grace, Battistoni, Elena T, Hall, David, Foulger, Anna, Lucanic, Mark, Guo, Max, Driscoll, Monica, Phillips, Patrick, Lithgow, Gordon J
Publicado 2021

Caenorhabditis Intervention Testing Program: the farnesoid X receptor agonist obeticholic acid does not robustly extend lifespan in nematodes

por Morshead, Mackenzie L, Sedore, Christine A, Jones, E Grace, Hall, David, Plummer, W Todd, Garrett, Theo, Lucanic, Mark, Guo, Max, Driscoll, Monica, Phillips, Patrick C, Lithgow, Gordon
Publicado 2020

A simplified design for the C. elegans lifespan machine

por Abbott, Mark, Banse, Stephen A., Melentijevic, Ilija, Jarrett, Cody M., Ange, Jonathan St., Sedore, Christine A., Falkowski, Ron, Blue, Benjamin W., Coleman-Hulbert, Anna L., Johnson, Erik, Guo, Max, Lithgow, Gordon J., Phillips, Patrick C., Driscoll, Monica
Publicado 2020

Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes

por Onken, Brian, Sedore, Christine A., Coleman‐Hulbert, Anna L., Hall, David, Johnson, Erik, Jones, Eleanor Grace, Banse, Stephen A., Huynh, Phu, Guo, Suzhen, Xue, Jian, Chen, Esteban, Harinath, Girish, Foulger, Anna C., Chao, Elizabeth A., Hope, June, Bhaumik, Dipa, Plummer, Todd, Inman, Delaney, Morshead, Mackenzie, Guo, Max, Lithgow, Gordon J., Phillips, Patrick C., Driscoll, Monica
Publicado 2021

Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions

por Banse, Stephen A., Lucanic, Mark, Sedore, Christine A., Coleman-Hulbert, Anna L., Plummer, W. Todd, Chen, Esteban, Kish, Jason L., Hall, David, Onken, Brian, Presley, Michael P., Jones, E. Grace, Blue, Benjamin W., Garrett, Theo, Abbott, Mark, Xue, Jian, Guo, Suzhen, Johnson, Erik, Foulger, Anna C., Chamoli, Manish, Falkowski, Ron, Melentijevic, Ilija, Harinath, Girish, Huynh, Phu, Patel, Shobhna, Edgar, Daniel, Jarrett, Cody M., Guo, Max, Kapahi, Pankaj, Lithgow, Gordon J., Driscoll, Monica, Phillips, Patrick C.
Publicado 2019

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

por Lucanic, Mark, Plummer, W. Todd, Chen, Esteban, Harke, Jailynn, Foulger, Anna C., Onken, Brian, Coleman-Hulbert, Anna L., Dumas, Kathleen J., Guo, Suzhen, Johnson, Erik, Bhaumik, Dipa, Xue, Jian, Crist, Anna B., Presley, Michael P., Harinath, Girish, Sedore, Christine A., Chamoli, Manish, Kamat, Shaunak, Chen, Michelle K., Angeli, Suzanne, Chang, Christina, Willis, John H., Edgar, Daniel, Royal, Mary Anne, Chao, Elizabeth A., Patel, Shobhna, Garrett, Theo, Ibanez-Ventoso, Carolina, Hope, June, Kish, Jason L, Guo, Max, Lithgow, Gordon J., Driscoll, Monica, Phillips, Patrick C.
Publicado 2017