BCL10 – Bridging CARDs to Immune Activation

por Gehring, Torben, Seeholzer, Thomas, Krappmann, Daniel
Publicado 2018

TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions

por O’Neill, Thomas J., Gewies, Andreas, Seeholzer, Thomas, Krappmann, Daniel
Publicado 2023

BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation

por Seeholzer, Thomas, Kurz, Susanne, Schlauderer, Florian, Woods, Simone, Gehring, Torben, Widmann, Simon, Lammens, Katja, Krappmann, Daniel
Publicado 2018

Molecular architecture and regulation of BCL10-MALT1 filaments

por Schlauderer, Florian, Seeholzer, Thomas, Desfosses, Ambroise, Gehring, Torben, Strauss, Mike, Hopfner, Karl-Peter, Gutsche, Irina, Krappmann, Daniel, Lammens, Katja
Publicado 2018

A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells

por Yin, Hongli, Karayel, Ozge, Chao, Ying-Yin, Seeholzer, Thomas, Hamp, Isabel, Plettenburg, Oliver, Gehring, Torben, Zielinski, Christina, Mann, Matthias, Krappmann, Daniel
Publicado 2022

Human immune disorder associated with homozygous hypomorphic mutation affecting MALT1B splice variant

por Kutukculer, Necil, Seeholzer, Thomas, O’Neill, Thomas J., Graß, Carina, Aykut, Ayca, Karaca, Neslihan Edeer, Durmaz, Asude, Cogulu, Ozgur, Aksu, Guzide, Gehring, Torben, Gewies, Andreas, Krappmann, Daniel
Publicado 2021

Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer

por Di Pilato, Mauro, Gao, Yun, Sun, Yi, Fu, Amina, Grass, Carina, Seeholzer, Thomas, Feederle, Regina, Mazo, Irina, Kazer, Samuel W., Litchfield, Kevin, von Andrian, Ulrich H., Mempel, Thorsten R., Jenkins, Russell W., Krappmann, Daniel, Keller, Peter
Publicado 2023

Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells

por Meininger, Isabel, Griesbach, Richard A., Hu, Desheng, Gehring, Torben, Seeholzer, Thomas, Bertossi, Arianna, Kranich, Jan, Oeckinghaus, Andrea, Eitelhuber, Andrea C., Greczmiel, Ute, Gewies, Andreas, Schmidt-Supprian, Marc, Ruland, Jürgen, Brocker, Thomas, Heissmeyer, Vigo, Heyd, Florian, Krappmann, Daniel
Publicado 2016

Human T(H)17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation

por Chao, Ying-Yin, Puhach, Alisa, Frieser, David, Arunkumar, Mahima, Lehner, Laurens, Seeholzer, Thomas, Garcia-Lopez, Albert, van der Wal, Marlot, Fibi-Smetana, Silvia, Dietschmann, Axel, Sommermann, Thomas, Ćiković, Tamara, Taher, Leila, Gresnigt, Mark S., Vastert, Sebastiaan J., van Wijk, Femke, Panagiotou, Gianni, Krappmann, Daniel, Groß, Olaf, Zielinski, Christina E.
Publicado 2023

Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation

por Cho, Jonathan J., Xu, Zhiwei, Parthasarathy, Upasana, Drashansky, Theodore T., Helm, Eric Y., Zuniga, Ashley N., Lorentsen, Kyle J., Mansouri, Samira, Cho, Joshua Y., Edelmann, Mariola J., Duong, Duc M., Gehring, Torben, Seeholzer, Thomas, Krappmann, Daniel, Uddin, Mohammad N., Califano, Danielle, Wang, Rejean L., Jin, Lei, Li, Hongmin, Lv, Dongwen, Zhou, Daohong, Zhou, Liang, Avram, Dorina
Publicado 2019