High-Resolution Mutation Mapping Reveals Parallel Experimental Evolution in Yeast

por Segrè, Ayellet V, Murray, Andrew W, Leu, Jun-Yi
Publicado 2006

Pathways Targeted by Antidiabetes Drugs Are Enriched for Multiple Genes Associated With Type 2 Diabetes Risk

por Segrè, Ayellet V., Wei, Nancy, Altshuler, David, Florez, Jose C.
Publicado 2015

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

por Segrè, Ayellet V., Groop, Leif, Mootha, Vamsi K., Daly, Mark J., Altshuler, David
Publicado 2010

ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis

por Kang, Eun Yong, Park, Yurang, Li, Xiao, Segrè, Ayellet V., Han, Buhm, Eskin, Eleazar
Publicado 2016

Interaction of background genetic risk, psychotropic medications, and primary angle closure glaucoma in the UK Biobank

por Sekimitsu, Sayuri, Wang, Jiali, Elze, Tobias, Segrè, Ayellet V., Wiggs, Janey L., Zebardast, Nazlee
Publicado 2022

TRANSCRIPTOMIC ANALYSIS OF THE OCULAR POSTERIOR SEGMENT COMPLETES A CELL ATLAS OF THE HUMAN EYE

por Monavarfeshani, Aboozar, Yan, Wenjun, Pappas, Christian, Odenigbo, Kenechukwu A., He, Zhigang, Segrè, Ayellet V., van Zyl, Tavé, Hageman, Gregory S., Sanes, Joshua R.
Publicado 2023

TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study

por Rajasundaram, Skanda, Zebardast, Nazlee, Mehta, Puja, Khawaja, Anthony P., Warwick, Alasdair, Duchinski, Katherine, Burgess, Stephen, Gill, Dipender, Segrè, Ayellet V., Wiggs, Janey
Publicado 2023

Polygenic Risk Score Improves Prediction of Primary Open Angle Glaucoma Onset in the Ocular Hypertension Treatment Study

por Singh, Rishabh K., Zhao, Yan, Elze, Tobias, Fingert, John, Gordon, Mae, Kass, Michael A., Luo, Yuyang, Pasquale, Louis R., Scheetz, Todd, Segrè, Ayellet V., Wiggs, Janey L., Zebardast, Nazlee
Publicado 2023

Predicting molecular mechanisms of hereditary diseases by using their tissue‐selective manifestation

por Simonovsky, Eyal, Sharon, Moran, Ziv, Maya, Mauer, Omry, Hekselman, Idan, Jubran, Juman, Vinogradov, Ekaterina, Argov, Chanan M, Basha, Omer, Kerber, Lior, Yogev, Yuval, Segrè, Ayellet V, Im, Hae Kyung, Birk, Ohad, Rokach, Lior, Yeger‐Lotem, Esti
Publicado 2023

Identification of Novel Type 2 Diabetes Candidate Genes Involved in the Crosstalk between the Mitochondrial and the Insulin Signaling Systems

por Mercader, Josep M., Puiggros, Montserrat, Segrè, Ayellet V., Planet, Evarist, Sorianello, Eleonora, Sebastian, David, Rodriguez-Cuenca, Sergio, Ribas, Vicent, Bonàs-Guarch, Sílvia, Draghici, Sorin, Yang, Chenjing, Mora, Sílvia, Vidal-Puig, Antoni, Dupuis, Josée, Florez, Jose C., Zorzano, Antonio, Torrents, David
Publicado 2012

Insights into human health from phenome- and genome-wide analyses of UK Biobank retinal optical coherence tomography phenotypes

por Zekavat, Seyedeh Maryam, Jorshery, Saman Doroodgar, Shweikh, Yusrah, Horn, Katrin, Rauscher, Franziska G., Sekimitsu, Sayuri, Kayoma, Satoshi, Ye, Yixuan, Raghu, Vineet, Zhao, Hongyu, Ghassemi, Marzyeh, Elze, Tobias, Segrè, Ayellet V., Wiggs, Janey L., Scholz, Markus, Priore, Lucian Del, Wang, Jay C., Natarajan, Pradeep, Zebardast, Nazlee
Publicado 2023

Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease

por Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar
Publicado 2017

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

por Gamazon, Eric R., Segrè, Ayellet V., van de Bunt, Martijn, Wen, Xiaoquan, Xi, Hualin S., Hormozdiari, Farhad, Ongen, Halit, Konkashbaev, Anuar, Derks, Eske M., Aguet, François, Quan, Jie, Nicolae, Dan L., Eskin, Eleazar, Kellis, Manolis, Getz, Gad, McCarthy, Mark I., Dermitzakis, Emmanouil T., Cox, Nancy J., Ardlie, Kristin G.
Publicado 2018

Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature

por Zekavat, Seyedeh Maryam, Raghu, Vineet K., Trinder, Mark, Ye, Yixuan, Koyama, Satoshi, Honigberg, Michael C., Yu, Zhi, Pampana, Akhil, Urbut, Sarah, Haidermota, Sara, O’Regan, Declan P., Zhao, Hongyu, Ellinor, Patrick T., Segrè, Ayellet V., Elze, Tobias, Wiggs, Janey L., Martone, James, Adelman, Ron A., Zebardast, Nazlee, Del Priore, Lucian, Wang, Jay C., Natarajan, Pradeep
Publicado 2021

Exploiting the GTEx resources to decipher the mechanisms at GWAS loci

por Barbeira, Alvaro N., Bonazzola, Rodrigo, Gamazon, Eric R., Liang, Yanyu, Park, YoSon, Kim-Hellmuth, Sarah, Wang, Gao, Jiang, Zhuoxun, Zhou, Dan, Hormozdiari, Farhad, Liu, Boxiang, Rao, Abhiram, Hamel, Andrew R., Pividori, Milton D., Aguet, François, Bastarache, Lisa, Jordan, Daniel M., Verbanck, Marie, Do, Ron, Stephens, Matthew, Ardlie, Kristin, McCarthy, Mark, Montgomery, Stephen B., Segrè, Ayellet V., Brown, Christopher D., Lappalainen, Tuuli, Wen, Xiaoquan, Im, Hae Kyung
Publicado 2021

Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci

por Han, Xikun, Gharahkhani, Puya, Hamel, Andrew R., Ong, Jue Sheng, Rentería, Miguel E., Mehta, Puja, Dong, Xianjun, Pasutto, Francesca, Hammond, Christopher, Young, Terri L., Hysi, Pirro, Lotery, Andrew J., Jorgenson, Eric, Choquet, Hélène, Hauser, Michael, Cooke Bailey, Jessica N., Nakazawa, Toru, Akiyama, Masato, Shiga, Yukihiro, Fuller, Zachary L., Wang, Xin, Hewitt, Alex W., Craig, Jamie E., Pasquale, Louis R., Mackey, David A., Wiggs, Janey L., Khawaja, Anthony P., Segrè, Ayellet V., MacGregor, Stuart
Publicado 2023

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

por Carithers, Latarsha J., Ardlie, Kristin, Barcus, Mary, Branton, Philip A., Britton, Angela, Buia, Stephen A., Compton, Carolyn C., DeLuca, David S., Peter-Demchok, Joanne, Gelfand, Ellen T., Guan, Ping, Korzeniewski, Greg E., Lockhart, Nicole C., Rabiner, Chana A., Rao, Abhi K., Robinson, Karna L., Roche, Nancy V., Sawyer, Sherilyn J., Segrè, Ayellet V., Shive, Charles E., Smith, Anna M., Sobin, Leslie H., Undale, Anita H., Valentino, Kimberly M., Vaught, Jim, Young, Taylor R., Moore, Helen M.
Publicado 2015

Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

por Mäkinen, Ville-Petteri, Civelek, Mete, Meng, Qingying, Zhang, Bin, Zhu, Jun, Levian, Candace, Huan, Tianxiao, Segrè, Ayellet V., Ghosh, Sujoy, Vivar, Juan, Nikpay, Majid, Stewart, Alexandre F. R., Nelson, Christopher P., Willenborg, Christina, Erdmann, Jeanette, Blakenberg, Stefan, O'Donnell, Christopher J., März, Winfried, Laaksonen, Reijo, Epstein, Stephen E., Kathiresan, Sekar, Shah, Svati H., Hazen, Stanley L., Reilly, Muredach P., Lusis, Aldons J., Samani, Nilesh J., Schunkert, Heribert, Quertermous, Thomas, McPherson, Ruth, Yang, Xia, Assimes, Themistocles L.
Publicado 2014

Erratum. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes 2019;68:441—456...

por Pollack, Samuela, Igo, Robert P., Jensen, Richard A., Christiansen, Mark, Li, Xiaohui, Cheng, Ching-Yu, Ng, Maggie C.Y., Smith, Albert V., Rossin, Elizabeth J., Segrè, Ayellet V., Davoudi, Samaneh, Tan, Gavin S., Ida Chen, Yii-Der, Kuo, Jane Z., Dimitrov, Latchezar M., Stanwyck, Lynn K., Meng, Weihua, Hosseini, S. Mohsen, Imamura, Minako, Nousome, Darryl, Kim, Jihye, Hai, Yang, Jia, Yucheng, Ahn, Jeeyun, Leong, Aaron, Shah, Kaanan, Park, Kyu Hyung, Guo, Xiuqing, Ipp, Eli, Taylor, Kent D., Adler, Sharon G., Sedor, John R., Freedman, Barry I., Lee, I-Te, Sheu, Wayne H.-H., Kubo, Michiaki, Takahashi, Atsushi, Hadjadj, Samy, Marre, Michel, Tregouet, David-Alexandre, Mckean-Cowdin, Roberta, Varma, Rohit, McCarthy, Mark I., Groop, Leif, Ahlqvist, Emma, Lyssenko, Valeriya, Agardh, Elisabet, Morris, Andrew, Doney, Alex S.F., Colhoun, Helen M., Toppila, Iiro, Sandholm, Niina, Groop, Per-Henrik, Maeda, Shiro, Hanis, Craig L., Penman, Alan, Chen, Ching J., Hancock, Heather, Mitchell, Paul, Craig, Jamie E., Chew, Emily Y., Paterson, Andrew D., Grassi, Michael A., Palmer, Colin, Bowden, Donald W., Yaspan, Brian L., Siscovick, David, Cotch, Mary Frances, Wang, Jie Jin, Burdon, Kathryn P., Wong, Tien Y., Klein, Barbara E.K., Klein, Ronald, Rotter, Jerome I., Iyengar, Sudha K., Price, Alkes L., Sobrin, Lucia
Publicado 2020

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

por Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.
Publicado 2021