Mouse IgG2a Isotype Therapeutic Antibodies Elicit Superior Tumor Growth Control Compared with mIgG1 or mIgE

por Vukovic, Natasa, Segués, Aina, Huang, Shuyu, Waterfall, Martin, Sijts, Alice J.A.M., Zaiss, Dietmar M.
Publicado 2023

Shortened Hinge Design of Fab x sdAb-Fc Bispecific Antibodies Enhances Redirected T-Cell Killing of Tumor Cells

por Huang, Shuyu, Segués, Aina, Waterfall, Martin, Wright, David, Vayssiere, Charlotte, van Duijnhoven, Sander M. J., van Elsas, Andrea, Sijts, Alice J. A. M., Zaiss, Dietmar M.
Publicado 2022

Intratumoral injection of IL-12-encoding mRNA targeted to CSFR1 and PD-L1 exerts potent anti-tumor effects without substantial systemic exposure

por Di Trani, Claudia Augusta, Cirella, Assunta, Arrizabalaga, Leire, Alvarez, Maite, Bella, Ángela, Fernandez-Sendin, Myriam, Russo-Cabrera, Joan Salvador, Gomar, Celia, Ardaiz, Nuria, Teijeira, Alvaro, Bolaños, Elixabet, González-Gomariz, José, Otano, Itziar, Aranda, Fernando, Palencia, Belén, Segués, Aina, Huang, Shuyu, van Duijnhoven, Sander M.J., van Elsas, Andrea, Melero, Ignacio, Berraondo, Pedro
Publicado 2023