Discovery of a Novel l-Lyxonate Degradation Pathway in Pseudomonas aeruginosa PAO1

por Ghasempur, Salehe, Eswaramoorthy, Subramaniam, Hillerich, Brandan S., Seidel, Ronald D., Swaminathan, Subramanyam, Almo, Steven C., Gerlt, John A.
Publicado 2014

Prospecting for Unannotated Enzymes: Discovery of a 3′,5′-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily

por Cummings, Jennifer A., Vetting, Matthew, Ghodge, Swapnil V., Xu, Chengfu, Hillerich, Brandan, Seidel, Ronald D., Almo, Steven C., Raushel, Frank M.
Publicado 2014

Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes

por Pan, Jian-Jung, Solbiati, Jose O., Ramamoorthy, Gurusankar, Hillerich, Brandan S., Seidel, Ronald D., Cronan, John E., Almo, Steven C., Poulter, C. Dale
Publicado 2015

Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase

por Vladimirova, Anna, Patskovsky, Yury, Fedorov, Alexander A., Bonanno, Jeffrey B., Fedorov, Elena V., Toro, Rafael, Hillerich, Brandan, Seidel, Ronald D., Richards, Nigel G. J., Almo, Steven C., Raushel, Frank M.
Publicado 2015

Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex

por Garrett-Thomson, Sarah C., Massimi, Aldo, Fedorov, Elena V., Bonanno, Jeffrey B., Scandiuzzi, Lisa, Hillerich, Brandan, Seidel, Ronald D., Love, James D., Garforth, Scott J., Guha, Chandan, Almo, Steven C.
Publicado 2020

A glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm

por Piszczatowski, Richard T., Schwenger, Emily, Sundaravel, Sriram, Stein, Catarina M., Liu, Yang, Stanley, Pamela, Verma, Amit, Zheng, Deyou, Seidel, Ronald D., Almo, Steven C., Townley, Robert A., Bülow, Hannes E., Steidl, Ulrich
Publicado 2022

Discovery of Function in the Enolase Superfamily: d-Mannonate and d-Gluconate Dehydratases in the d-Mannonate Dehydratase Subgroup

por Wichelecki, Daniel J., Balthazor, Bryan M., Chau, Anthony C., Vetting, Matthew W., Fedorov, Alexander A., Fedorov, Elena V., Lukk, Tiit, Patskovsky, Yury V., Stead, Mark B., Hillerich, Brandan S., Seidel, Ronald D., Almo, Steven C., Gerlt, John A.
Publicado 2014

Large-Scale Determination of Sequence, Structure, and Function Relationships in Cytosolic Glutathione Transferases across the Biosphere

por Mashiyama, Susan T., Malabanan, M. Merced, Akiva, Eyal, Bhosle, Rahul, Branch, Megan C., Hillerich, Brandan, Jagessar, Kevin, Kim, Jungwook, Patskovsky, Yury, Seidel, Ronald D., Stead, Mark, Toro, Rafael, Vetting, Matthew W., Almo, Steven C., Armstrong, Richard N., Babbitt, Patricia C.
Publicado 2014

Peptide-HLA-based immunotherapeutics platforms for direct modulation of antigen-specific T cells

por Seidel, Ronald D., Merazga, Zohra, Thapa, Dharma Raj, Soriano, Jonathan, Spaulding, Emily, Vakkasoglu, Ahmet S., Ruthardt, Paige, Bautista, Wynona, Quayle, Steven N., Kiener, Peter A., Low, Simon, Ross, John F., Cemerski, Saso, Suri, Anish, Almo, Steven C., Chaparro, Rodolfo J.
Publicado 2021

Discovery of new enzymes and metabolic pathways using structure and genome context

por Zhao, Suwen, Kumar, Ritesh, Sakai, Ayano, Vetting, Matthew W., Wood, B. McKay, Brown, Shoshana, Bonanno, Jeffery B., Hillerich, Brandan S., Seidel, Ronald D., Babbitt, Patricia C., Almo, Steven C., Sweedler, Jonathan V., Gerlt, John A., Cronan, John E., Jacobson, Matthew P.
Publicado 2013

Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

por Zhao, Suwen, Sakai, Ayano, Zhang, Xinshuai, Vetting, Matthew W, Kumar, Ritesh, Hillerich, Brandan, San Francisco, Brian, Solbiati, Jose, Steves, Adam, Brown, Shoshana, Akiva, Eyal, Barber, Alan, Seidel, Ronald D, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P
Publicado 2014

Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes

por Vetting, Matthew W., Al-Obaidi, Nawar, Zhao, Suwen, San Francisco, Brian, Kim, Jungwook, Wichelecki, Daniel J., Bouvier, Jason T., Solbiati, Jose O., Vu, Hoan, Zhang, Xinshuai, Rodionov, Dmitry A., Love, James D., Hillerich, Brandan S., Seidel, Ronald D., Quinn, Ronald J., Osterman, Andrei L., Cronan, John E., Jacobson, Matthew P., Gerlt, John A., Almo, Steven C.
Publicado 2014