Maximizing Completion of the Two-Dose COVID-19 Vaccine Series with Aid from Infographics

por Crutcher, Madison, Seidler, Paul M.
Publicado 2021

Selective inhibition of hsp90 paralogs: Structure and binding studies uncover the role of helix 1 in Grp94-selective ligand binding

por Que, Nanette L. S., Seidler, Paul M., Aw, Wen J., Chiosis, Gabriela, Gewirth, Daniel T.
Publicado 2023

Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation

por Shin, Woo Shik, Di, Jing, Cao, Qin, Li, Binsen, Seidler, Paul M., Murray, Kevin A., Bitan, Gal, Jiang, Lin
Publicado 2019

Correction to: Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation

por Shin, Woo Shik, Di, Jing, Cao, Qin, Li, Binsen, Seidler, Paul M., Murray, Kevin A., Bitan, Gal, Jiang, Lin
Publicado 2021

Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies

por Murray, Kevin A., Hughes, Michael P., Hu, Carolyn J., Sawaya, Michael R., Salwinski, Lukasz, Pan, Hope, French, Samuel W., Seidler, Paul M., Eisenberg, David S.
Publicado 2022

De novo designed protein inhibitors of amyloid aggregation and seeding

por Murray, Kevin A., Hu, Carolyn J., Griner, Sarah L., Pan, Hope, Bowler, Jeannette T., Abskharon, Romany, Rosenberg, Gregory M., Cheng, Xinyi, Seidler, Paul M., Eisenberg, David S.
Publicado 2022

A heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters: discovery of the Aspergillus fumigatus sa...

por Lin, Shu-Yi, Oakley, C. Elizabeth, Jenkinson, Cory B., Chiang, Yi-Ming, Lee, Ching-Kuo, Jones, Christopher G., Seidler, Paul M., Nelson, Hosea M., Todd, Richard B., Wang, Clay C. C., Oakley, Berl R.
Publicado 2023

Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils

por Murray, Kevin A., Hu, Carolyn J., Pan, Hope, Lu, Jiahui, Abskharon, Romany, Bowler, Jeannette T., Rosenberg, Gregory M., Williams, Christopher K., Elezi, Gazmend, Balbirnie, Melinda, Faull, Kym F., Vinters, Harry V., Seidler, Paul M., Eisenberg, David S.
Publicado 2023

Structure-based discovery of small molecules that disaggregate Alzheimer’s disease tissue derived tau fibrils in vitro

por Seidler, Paul M., Murray, Kevin A., Boyer, David R., Ge, Peng, Sawaya, Michael R., Hu, Carolyn J., Cheng, Xinyi, Abskharon, Romany, Pan, Hope, DeTure, Michael A., Williams, Christopher K., Dickson, Dennis W., Vinters, Harry V., Eisenberg, David S.
Publicado 2022

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

por Tayeb-Fligelman, Einav, Bowler, Jeannette T., Tai, Christen E., Sawaya, Michael R., Jiang, Yi Xiao, Garcia, Gustavo, Griner, Sarah L., Cheng, Xinyi, Salwinski, Lukasz, Lutter, Liisa, Seidler, Paul M., Lu, Jiahui, Rosenberg, Gregory M., Hou, Ke, Abskharon, Romany, Pan, Hope, Zee, Chih-Te, Boyer, David R., Li, Yan, Anderson, Daniel H., Murray, Kevin A., Falcon, Genesis, Cascio, Duilio, Saelices, Lorena, Damoiseaux, Robert, Arumugaswami, Vaithilingaraja, Guo, Feng, Eisenberg, David S.
Publicado 2023

Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau fibrils

por Abskharon, Romany, Pan, Hope, Sawaya, Michael R., Seidler, Paul M., Olivares, Eileen J., Chen, Yu, Murray, Kevin A., Zhang, Jeffrey, Lantz, Carter, Bentzel, Megan, Boyer, David R., Cascio, Duilio, Nguyen, Binh A., Hou, Ke, Cheng, Xinyi, Pardon, Els, Williams, Christopher K., Nana, Alissa L., Vinters, Harry V., Spina, Salvatore, Grinberg, Lea T., Seeley, William W., Steyaert, Jan, Glabe, Charles G., Ogorzalek Loo, Rachel R., Loo, Joseph A., Eisenberg, David S.
Publicado 2023