Hypertrophic cardiomyopathy: Translating cellular cross talk into therapeutics

por Teekakirikul, Polakit, Padera, Robert F., Seidman, J.G., Seidman, Christine E.
Publicado 2012

Genes for two homologous G-protein α subunits map to different human chromosomes

por Neer, Eva J., Michel, Thomas, Eddy, Roger, Shows, Thomas, Seidman, J. G.
Publicado 1987

Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection

por Herman, Daniel S, Hovingh, G Kees, Iartchouk, Oleg, Rehm, Heidi L, Kucherlapati, Raju, Seidman, J G, Seidman, Christine E
Publicado 2009

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis

por Delgado-Olguín, Paul, Huang, Yu, Li, Xue, Christodoulou, Danos, Seidman, Christine E., Seidman, J.G., Tarakhovsky, Alexander, Bruneau, Benoit G.
Publicado 2012

poly(UG)-tailed RNAs in Genome Protection and Epigenetic Inheritance

por Shukla, Aditi, Yan, Jenny, Pagano, Daniel J., Dodson, Anne E., Fei, Yuhan, Gorham, Josh, Seidman, J.G., Wickens, Marvin, Kennedy, Scott
Publicado 2020

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro

por DeLaughter, Daniel M., Clark, Cynthia R., Christodoulou, Danos C., Seidman, Christine E., Baldwin, H. Scott, Seidman, J. G., Barnett, Joey V.
Publicado 2016

Dynamic Cellular Integration Drives Functional Assembly of the Heart’s Pacemaker Complex

por Bressan, Michael, Henley, Trevor, Louie, Jonathan D., Liu, Gary, Christodoulou, Danos, Bai, Xue, Taylor, Joan, Seidman, Christine E., Seidman, J.G., Mikawa, Takashi
Publicado 2018

NKX2-5 Mutations in an Inbred Consanguineous Population: Genetic and Phenotypic Diversity

por Abou Hassan, Ossama K., Fahed, Akl C., Batrawi, Manal, Arabi, Mariam, Refaat, Marwan M., DePalma, Steven R., Seidman, J. G., Seidman, Christine E., Bitar, Fadi F., Nemer, Georges M.
Publicado 2015

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

por Bick, Alexander G., Wakimoto, Hiroko, Kamer, Kimberli J., Sancak, Yasemin, Goldberger, Olga, Axelsson, Anna, DeLaughter, Daniel M., Gorham, Joshua M., Mootha, Vamsi K., Seidman, J. G., Seidman, Christine E.
Publicado 2017

Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

por Sun, Xin, Hota, Swetansu K., Zhou, Yu-Qing, Novak, Stefanie, Miguel-Perez, Dario, Christodoulou, Danos, Seidman, Christine E., Seidman, J. G., Gregorio, Carol C., Henkelman, R. Mark, Rossant, Janet, Bruneau, Benoit G.
Publicado 2017

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere

por Agarwal, Radhika, Wakimoto, Hiroko, Paulo, Joao A., Zhang, Qi, Reichart, Daniel, Toepfer, Christopher, Sharma, Arun, Tai, Angela C., Lun, Mingyue, Gorham, Joshua, DePalma, Steven R., Gygi, Steven P., Seidman, J.G., Seidman, Christine E.
Publicado 2022

Whole-Genome Sequencing as a First-Line Genetic Test in Familial Dilated Cardiomyopathy

por Minoche, Andre E., Horvat, Claire, Johnson, Renee, Gayevskiy, Velimir, Morton, Sarah U., Drew, Alexander P., Woo, Kerhan, Statham, Aaron L., Lundie, Ben, Bagnall, Richard D., Ingles, Jodie, Semsarian, Christopher, Seidman, J.G., Seidman, Christine E., Dinger, Marcel E., Cowley, Mark J., Fatkin, Diane
Publicado 2018

Genome-Wide Assessment for Genetic Variants Associated with Ventricular Dysfunction after Primary Coronary Artery Bypass Graft Surgery

por Fox, Amanda A., Pretorius, Mias, Liu, Kuang-Yu, Collard, Charles D., Perry, Tjorvi E., Shernan, Stanton K., De Jager, Philip L., Hafler, David A., Herman, Daniel S., DePalma, Steven R., Roden, Dan M., Muehlschlegel, Jochen D., Donahue, Brian S., Darbar, Dawood, Seidman, J. G., Body, Simon C., Seidman, Christine E.
Publicado 2011

The Role of Cardiac Troponin T Quantity and Function in Cardiac Development and Dilated Cardiomyopathy

por Ahmad, Ferhaan, Banerjee, Sanjay K., Lage, Michele L., Huang, Xueyin N., Smith, Stephen H., Saba, Samir, Rager, Jennifer, Conner, David A., Janczewski, Andrzej M., Tobita, Kimimasa, Tinney, Joseph P., Moskowitz, Ivan P., Perez-Atayde, Antonio R., Keller, Bradley B., Mathier, Michael A., Shroff, Sanjeev G., Seidman, Christine E., Seidman, J. G.
Publicado 2008

Loss of RNA expression and allele-specific expression associated with congenital heart disease

por McKean, David M., Homsy, Jason, Wakimoto, Hiroko, Patel, Neil, Gorham, Joshua, DePalma, Steven R., Ware, James S., Zaidi, Samir, Ma, Wenji, Patel, Nihir, Lifton, Richard P., Chung, Wendy K., Kim, Richard, Shen, Yufeng, Brueckner, Martina, Goldmuntz, Elizabeth, Sharp, Andrew J., Seidman, Christine E., Gelb, Bruce D., Seidman, J. G.
Publicado 2016

An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations

por Quiat, Daniel, Kim, Seong Won, Zhang, Qi, Morton, Sarah U., Pereira, Alexandre C., DePalma, Steven R., Willcox, Jon A. L., McDonough, Barbara, DeLaughter, Daniel M., Gorham, Joshua M., Curran, Justin J., Tumblin, Melissa, Nicolau, Yamileth, Artunduaga, Maria A., Quintanilla-Dieck, Lourdes, Osorno, Gabriel, Serrano, Luis, Hamdan, Usama, Eavey, Roland D., Seidman, Christine E., Seidman, J. G.
Publicado 2022

Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease

por Morton, Sarah U., Shimamura, Akiko, Newburger, Peter E., Opotowsky, Alexander R., Quiat, Daniel, Pereira, Alexandre C., Jin, Sheng Chih, Gurvitz, Michelle, Brueckner, Martina, Chung, Wendy K., Shen, Yufeng, Bernstein, Daniel, Gelb, Bruce D., Giardini, Alessandro, Goldmuntz, Elizabeth, Kim, Richard W., Lifton, Richard P., Porter, George A., Srivastava, Deepak, Tristani-Firouzi, Martin, Newburger, Jane W., Seidman, J. G., Seidman, Christine E.
Publicado 2020

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model

por Axelsson Raja, Anna, Wakimoto, Hiroko, DeLaughter, Daniel M., Reichart, Daniel, Gorham, Joshua, Conner, David A., Lun, Mingyue, Probst, Clemens K., Sakai, Norihiko, Knipe, Rachel S., Montesi, Sydney B., Shea, Barry, Adam, Leonard P., Leinwand, Leslie A., Wan, William, Choi, Esther Sue, Lindberg, Eric L., Patone, Giannino, Noseda, Michela, Hübner, Norbert, Seidman, Christine E., Tager, Andrew M., Seidman, J. G., Ho, Carolyn Y.
Publicado 2022

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease

por Hsieh, Alexander, Morton, Sarah U., Willcox, Jon A. L., Gorham, Joshua M., Tai, Angela C., Qi, Hongjian, DePalma, Steven, McKean, David, Griffin, Emily, Manheimer, Kathryn B., Bernstein, Daniel, Kim, Richard W., Newburger, Jane W., Porter, George A., Srivastava, Deepak, Tristani-Firouzi, Martin, Brueckner, Martina, Lifton, Richard P., Goldmuntz, Elizabeth, Gelb, Bruce D., Chung, Wendy K., Seidman, Christine E., Seidman, J. G., Shen, Yufeng
Publicado 2020

De Novo Copy Number Variants Identify New Genes and Loci in Isolated, Sporadic Tetralogy of Fallot

por Greenway, Steven C, Pereira, Alexandre C, Lin, Jennifer C, DePalma, Steven R, Israel, Samuel J, Mesquita, Sonia M, Ergul, Emel, Conta, Jessie R, Korn, Joshua M, McCarroll, Steven A, Gorham, Joshua M, Gabriel, Stacey, Altshuler, David A, de Lourdes Quintanilla-Dieck, Maria, Artunduaga, Maria Alexandra, Eavey, Roland D, Plenge, Robert M, Shadick, Nancy A, Weinblatt, Michael E, De Jager, Philip L, Hafler, David A, Breitbart, Roger E, Seidman, J G, Seidman, Christine E
Publicado 2009