Foundations for architecting data solutions: managing successful data projects

por Malaska, Ted, Seidman, Jonathan
Publicado 2018

Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases

por Rios, Xavier, Briggs, Adrian W., Christodoulou, Danos, Gorham, Josh M., Seidman, Jonathan G., Church, George M.
Publicado 2012

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes

por Alamo, Lorenzo, Ware, James S, Pinto, Antonio, Gillilan, Richard E, Seidman, Jonathan G, Seidman, Christine E, Padrón, Raúl
Publicado 2017

PC16. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia

por Timberlake, Andrew T., Quiat, Daniel, Cunningham, Michael L., Persing, John, Luquetti, Daniela, Heike, Carrie L., Seidman, Jonathan, Seidman, Christine
Publicado 2023

1. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia

por Timberlake, Andrew T., Quiat, Daniel, Cunningham, Michael, Persing, John, Luquetti, Daniela V., Heike, Carrie L., Seidman, Jonathan, Seidman, Christine
Publicado 2023

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

por Zhang, Bing, Day, Daniel S., Ho, Joshua W., Song, Lingyun, Cao, Jingjing, Christodoulou, Danos, Seidman, Jonathan G., Crawford, Gregory E., Park, Peter J., Pu, William T.
Publicado 2013

Engineering a living cardiac pump on a chip using high-precision fabrication

por Michas, Christos, Karakan, M. Çağatay, Nautiyal, Pranjal, Seidman, Jonathan G., Seidman, Christine E., Agarwal, Arvind, Ekinci, Kamil, Eyckmans, Jeroen, White, Alice E., Chen, Christopher S.
Publicado 2022

ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients

por Chalkias, Spyros, Gorham, Joshua M., Mazaika, Erica, Parfenov, Michael, Dang, Xin, DePalma, Steve, McKean, David, Seidman, Christine E., Seidman, Jonathan G., Koralnik, Igor J.
Publicado 2018

Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers

por Adalsteinsdottir, Berglind, Burke, Michael, Maron, Barry J, Danielsen, Ragnar, Lopez, Begoña, Diez, Javier, Jarolim, Petr, Seidman, Jonathan, Seidman, Christine E., Ho, Carolyn Y, Gunnarsson, Gunnar Th
Publicado 2020

Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

por Onoue, Kenji, Wakimoto, Hiroko, Jiang, Jiangming, Parfenov, Michael, DePalma, Steven, Conner, David, Gorham, Joshua, McKean, David, Seidman, Jonathan G., Seidman, Christine E., Saito, Yoshihiko
Publicado 2021

Genetic profiling of fatty acid desaturase polymorphisms identifies patients who may benefit from high-dose omega-3 fatty acids in cardiac remodeling after acute myocardial infarct...

por Kwong, Raymond Y., Heydari, Bobak, Ge, Yin, Abdullah, Shuaib, Fujikura, Kana, Kaneko, Kyoichi, Harris, William S., Jerosch-Herold, Michael, Antman, Elliott M., Seidman, Jonathan G., Pfeffer, Marc A.
Publicado 2019

Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1

por Shi, Wei, Scialdone, Angel P., Emerson, James I., Mei, Liu, Wasson, Lauren K., Davies, Haley A., Seidman, Christine E., Seidman, Jonathan G., Cook, Jeanette G., Conlon, Frank L.
Publicado 2023

The Role of the L-Type Ca(2+) Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy

por Viola, Helena M., Johnstone, Victoria P.A., Cserne Szappanos, Henrietta, Richman, Tara R., Tsoutsman, Tatiana, Filipovska, Aleksandra, Semsarian, Christopher, Seidman, Jonathan G., Seidman, Christine E., Hool, Livia C.
Publicado 2016

Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans

por Zhang, Hao, Jamieson, K. Lockhart, Grenier, Justin, Nikhanj, Anish, Tang, Zeyu, Wang, Faqi, Wang, Shaohua, Seidman, Jonathan G., Seidman, Christine E., Thompson, Richard, Seubert, John M., Oudit, Gavin Y.
Publicado 2022

Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells

por Yang, Luhan, Grishin, Dennis, Wang, Gang, Aach, John, Zhang, Cheng-Zhong, Chari, Raj, Homsy, Jason, Cai, Xuyu, Zhao, Yue, Fan, Jian-Bing, Seidman, Christine, Seidman, Jonathan, Pu, William, Church, George
Publicado 2014

Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue

por Javor, Josh, Ewoldt, Jourdan K., Cloonan, Paige E., Chopra, Anant, Luu, Rebeccah J., Freychet, Guillaume, Zhernenkov, Mikhail, Ludwig, Karl, Seidman, Jonathan G., Seidman, Christine E., Chen, Christopher S., Bishop, David J.
Publicado 2021

Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy

por Oliveira, Theo G. M., Venturini, Gabriela, Alvim, Juliana M., Feijó, Larissa L., Dinardo, Carla L., Sabino, Ester C., Seidman, Jonathan G., Seidman, Christine E., Krieger, Jose E., Pereira, Alexandre C.
Publicado 2022

A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects

por Kamar, Amina, Fahed, Akl C., Shibbani, Kamel, El-Hachem, Nehme, Bou-Slaiman, Salim, Arabi, Mariam, Kurban, Mazen, Seidman, Jonathan G., Seidman, Christine E., Haidar, Rachid, Baydoun, Elias, Nemer, Georges, Bitar, Fadi
Publicado 2017

Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy

por Margara, Francesca, Psaras, Yiangos, Wang, Zhinuo Jenny, Schmid, Manuel, Doste, Ruben, Garfinkel, Amanda C., Repetti, Giuliana G., Seidman, Jonathan G., Seidman, Christine E., Rodriguez, Blanca, Toepfer, Christopher N., Bueno-Orovio, Alfonso
Publicado 2022

Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation–Contraction Coupling

por Moore, Jarrod, Ewoldt, Jourdan, Venturini, Gabriela, Pereira, Alexandre C., Padilha, Kallyandra, Lawton, Matthew, Lin, Weiwei, Goel, Raghuveera, Luptak, Ivan, Perissi, Valentina, Seidman, Christine E., Seidman, Jonathan, Chin, Michael T., Chen, Christopher, Emili, Andrew
Publicado 2023