TIGIT Expression Delineates T-cell Populations with Distinct Functional and Prognostic Impact in Pancreatic Cancer

por Heiduk, Max, Klimova, Anna, Reiche, Charlotte, Digomann, David, Beer, Carolin, Aust, Daniela E., Distler, Marius, Weitz, Jürgen, Seifert, Adrian M., Seifert, Lena
Publicado 2023

Interrupted versus continuous suture technique for biliary-enteric anastomosis: randomized clinical trial

por Seifert, Lena, von Renesse, Janusz, Seifert, Adrian M, Sturm, Dorothée, Meisterfeld, Ronny, Rahbari, Nuh N, Kahlert, Christoph, Distler, Marius, Weitz, Jürgen, Reissfelder, Christoph
Publicado 2023

Gamma-delta T cells stimulate IL-6 production by pancreatic stellate cells in pancreatic ductal adenocarcinoma

por Seifert, Adrian M., List, Julian, Heiduk, Max, Decker, Rahel, von Renesse, Janusz, Meinecke, Ann-Christin, Aust, Daniela E., Welsch, Thilo, Weitz, Jürgen, Seifert, Lena
Publicado 2020

Energy requirements of long-term ventilated COVID-19 patients with resolved SARS-CoV-2 infection

por von Renesse, Janusz, von Bonin, Simone, Held, Hanns-Christoph, Schneider, Ralph, Seifert, Adrian M., Seifert, Lena, Spieth, Peter, Weitz, Jürgen, Welsch, Thilo, Meisterfeld, Ronny
Publicado 2021

LAG-3-Expressing Tumor-Infiltrating T Cells Are Associated with Reduced Disease-Free Survival in Pancreatic Cancer

por Seifert, Lena, Plesca, Ioana, Müller, Luise, Sommer, Ulrich, Heiduk, Max, von Renesse, Janusz, Digomann, David, Glück, Jessica, Klimova, Anna, Weitz, Jürgen, Schmitz, Marc, Seifert, Adrian M.
Publicado 2021

VISTA Ligation Reduces Antitumor T-Cell Activity in Pancreatic Cancer

por Digomann, David, Strack, Johannes, Heiduk, Max, Plesca, Ioana, Rupp, Luise, Reiche, Charlotte, Nicolaus, Simone, Beer, Carolin, Sommer, Ulrich, Schmitz, Marc, Distler, Marius, Weitz, Jürgen, Seifert, Adrian M., Seifert, Lena
Publicado 2023

Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer

por Digomann, David, Heiduk, Max, Reiche, Charlotte, Glück, Jessica, Kahlert, Christoph, Mirtschink, Peter, Klimova, Anna, Bösch, Florian, Tonn, Torsten, Gaedcke, Jochen, Ghadimi, Michael, Weitz, Jürgen, Seifert, Lena, Seifert, Adrian M.
Publicado 2023

PD-1 Expression by Lymph Node and Intratumoral Regulatory T Cells Is Associated with Lymph Node Metastasis in Pancreatic Cancer

por Seifert, Adrian M., Eymer, Annabel, Heiduk, Max, Wehner, Rebekka, Tunger, Antje, von Renesse, Janusz, Decker, Rahel, Aust, Daniela E., Welsch, Thilo, Reissfelder, Christoph, Weitz, Jürgen, Schmitz, Marc, Seifert, Lena
Publicado 2020

Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma

por Plesca, Ioana, Benešová, Iva, Beer, Carolin, Sommer, Ulrich, Müller, Luise, Wehner, Rebekka, Heiduk, Max, Aust, Daniela, Baretton, Gustavo, Bachmann, Michael P, Feldmann, Anja, Weitz, Jürgen, Seifert, Lena, Seifert, Adrian M, Schmitz, Marc
Publicado 2022

Neoadjuvant chemotherapy drives intratumoral T cells toward a proinflammatory profile in pancreatic cancer

por Heiduk, Max, Plesca, Ioana, Glück, Jessica, Müller, Luise, Digomann, David, Reiche, Charlotte, von Renesse, Janusz, Decker, Rahel, Kahlert, Christoph, Sommer, Ulrich, Aust, Daniela E., Schmitz, Marc, Weitz, Jürgen, Seifert, Lena, Seifert, Adrian M.
Publicado 2022

ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumor

por Zeng, Shan, Seifert, Adrian M., Zhang, Jennifer Q., Kim, Teresa S., Bowler, Timothy G., Cavnar, Michael J., Medina, Benjamin D., Vitiello, Gerardo A., Rossi, Ferdinand, Loo, Jennifer K., Param, Nesteene J., DeMatteo, Ronald P.
Publicado 2017

Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels

por Seifert, Adrian M., Reiche, Charlotte, Heiduk, Max, Tannert, Anna, Meinecke, Ann-Christin, Baier, Stephanie, von Renesse, Janusz, Kahlert, Christoph, Distler, Marius, Welsch, Thilo, Reissfelder, Christoph, Aust, Daniela E., Miller, George, Weitz, Jürgen, Seifert, Lena
Publicado 2020

Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer

por Ganig, Nicole, Baenke, Franziska, Thepkaysone, May-Linn, Lin, Kuailu, Rao, Venkatesh S., Wong, Fang Cheng, Polster, Heike, Schneider, Martin, Helm, Dominic, Pecqueux, Mathieu, Seifert, Adrian M., Seifert, Lena, Weitz, Jürgen, Rahbari, Nuh N., Kahlert, Christoph
Publicado 2021

The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor

por Zhang, Jennifer Q., Bosbach, Benedikt, Loo, Jennifer K., Vitiello, Gerardo A., Zeng, Shan, Seifert, Adrian M., Medina, Benjamin D., Param, Nesteene J., Maltbaek, Joanna H., Rossi, Ferdinand, Antonescu, Cristina R., Besmer, Peter, DeMatteo, Ronald P.
Publicado 2020

Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells

por Santamaria-Barria, Juan A., Zeng, Shan, Greer, Jonathan B., Beckman, Michael J., Seifert, Adrian M., Cohen, Noah A., Zhang, Jennifer Q., Crawley, Megan H., Green, Benjamin L., Loo, Jennifer K., Maltbaek, Joanna H., DeMatteo, Ronald P.
Publicado 2019

Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation

por Sorenson, Eric C., Khanin, Raya, Bamboat, Zubin M., Cavnar, Michael J., Kim, Teresa S., Sadot, Eran, Zeng, Shan, Greer, Jonathan B., Seifert, Adrian M., Cohen, Noah A., Crawley, Megan H., Green, Benjamin L., Klimstra, David S., DeMatteo, Ronald P.
Publicado 2017

Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity

por Medina, Benjamin D., Liu, Mengyuan, Vitiello, Gerardo A., Seifert, Adrian M., Zeng, Shan, Bowler, Timothy, Zhang, Jennifer Q., Cavnar, Michael J., Loo, Jennifer K., Param, Nesteene J., Maltbaek, Joanna H., Rossi, Ferdinand, Balachandran, Vinod, DeMatteo, Ronald P.
Publicado 2019

Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer

por Kießler, Maximilian, Plesca, Ioana, Sommer, Ulrich, Wehner, Rebekka, Wilczkowski, Friederike, Müller, Luise, Tunger, Antje, Lai, Xixi, Rentsch, Anke, Peuker, Kenneth, Zeissig, Sebastian, Seifert, Adrian M, Seifert, Lena, Weitz, Jürgen, Bachmann, Michael, Bornhäuser, Martin, Aust, Daniela, Baretton, Gustavo, Schmitz, Marc
Publicado 2021

Tumour catabolism independent of malnutrition and inflammation in upper GI cancer patients revealed by longitudinal metabolomics

por von Renesse, Janusz, von Bechtolsheim, Felix, Jonas, Sophie, Seifert, Lena, Alves, Tiago C., Seifert, Adrian M., Komorek, Filip, Tritchkova, Guergana, Menschikowski, Mario, Bork, Ulrich, Meisterfeld, Ronny, Distler, Marius, Chavakis, Triantafyllos, Weitz, Jürgen, Funk, Alexander M., Kahlert, Christoph, Mirtschink, Peter
Publicado 2022

KIT oncogene inhibition drives intratumoral macrophage M2 polarization

por Cavnar, Michael J., Zeng, Shan, Kim, Teresa S., Sorenson, Eric C., Ocuin, Lee M., Balachandran, Vinod P., Seifert, Adrian M., Greer, Jonathan B., Popow, Rachel, Crawley, Megan H., Cohen, Noah A., Green, Benjamin L., Rossi, Ferdinand, Besmer, Peter, Antonescu, Cristina R., DeMatteo, Ronald P.
Publicado 2013