Enhanced Permeability and Binding Activity of Isobutylene‐Grafted Peptides

por Sun, Shuang, Compañón, Ismael, Martínez‐Sáez, Nuria, Seixas, João D., Boutureira, Omar, Corzana, Francisco, Bernardes, Gonçalo J. L.
Publicado 2017

Study of the interactions of bovine serum albumin with a molybdenum(II) carbonyl complex by spectroscopic and molecular simulation methods

por Jeremias, Hélia F., Lousa, Diana, Hollmann, Axel, Coelho, Ana C., Baltazar, Carla S., Seixas, João D., Marques, Ana R., Santos, Nuno C., Romão, Carlos C., Soares, Cláudio M.
Publicado 2018

An N-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species

por Seixas, João D, Chaves-Ferreira, Miguel, Montes-Grajales, Diana, Gonçalves, Ana M, Marques, Ana R, Saraiva, Lígia M, Olivero-Verbel, Jesus, Romão, Carlos C, Bernardes, Gonçalo J L
Publicado 2015

Establishment of a Structure–Activity Relationship of 1H-Imidazo[4,5-c]quinoline-Based Kinase Inhibitor NVP-BEZ235 as a Lead for African Sleeping Sickness

por Seixas, João D., Luengo-Arratta, Sandra A., Diaz, Rosario, Saldivia, Manuel, Rojas-Barros, Domingo I., Manzano, Pilar, Gonzalez, Silvia, Berlanga, Manuela, Smith, Terry K., Navarro, Miguel, Pollastri, Michael P.
Publicado 2014

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

por Diaz, Rosario, Luengo-Arratta, Sandra A., Seixas, João D., Amata, Emanuele, Devine, William, Cordon-Obras, Carlos, Rojas-Barros, Domingo I., Jimenez, Elena, Ortega, Fatima, Crouch, Sabrinia, Colmenarejo, Gonzalo, Fiandor, Jose Maria, Martin, Jose Julio, Berlanga, Manuela, Gonzalez, Silvia, Manzano, Pilar, Navarro, Miguel, Pollastri, Michael P.
Publicado 2014

Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

por Seixas, João D., Sousa, Bárbara B., Marques, Marta C., Guerreiro, Ana, Traquete, Rui, Rodrigues, Tiago, Albuquerque, Inês S., Sousa, Marcos F. Q., Lemos, Ana R., Sousa, Pedro M. F., Bandeiras, Tiago M., Wu, Di, Doyle, Shelby K., Robinson, Carol V., Koehler, Angela N., Corzana, Francisco, Matias, Pedro M., Bernardes, Gonçalo J. L.
Publicado 2020

Selective Inhibition of Bruton’s Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors

por Sousa, Bárbara B., de Almeida, Cátia Rebelo, Barahona, Ana F., Lopes, Raquel, Martins-Logrado, Ana, Cavaco, Marco, Neves, Vera, Carvalho, Luís A. R., Labão-Almeida, Carlos, Coelho, Ana R., Leal Bento, Marta, Lopes, Ricardo M. R. M., Oliveira, Bruno L., Castanho, Miguel A. R. B., Neumeister, Peter, Deutsch, Alexander, Vladimer, Gregory I., Krall, Nikolaus, João, Cristina, Corzana, Francisco, Seixas, João D., Fior, Rita, Bernardes, Gonçalo J. L.
Publicado 2022