L-Asparaginase-Induced Continuous Hyperglycemia With Type 1 Diabetes-Related Antibodies and HLA Genotypes: A Case Study

por Furuta, Yasuhisa, Yatoh, Shigeru, Iwasaki, Hitoshi, Sugano, Yoko, Sekiya, Motohiro, Suzuki, Hiroaki, Shimano, Hitoshi
Publicado 2022

Exploratory analysis using machine learning of predictive factors for falls in type 2 diabetes

por Suzuki, Yasuhiro, Suzuki, Hiroaki, Ishikawa, Tatsuya, Yamada, Yasunori, Yatoh, Shigeru, Sugano, Yoko, Iwasaki, Hitoshi, Sekiya, Motohiro, Yahagi, Naoya, Hada, Yasushi, Shimano, Hitoshi
Publicado 2022

Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells

por Yamazaki, Hisataka, Takahashi, Manabu, Wakabayashi, Tetsuji, Sakai, Kent, Yamamuro, Daisuke, Takei, Akihito, Takei, Shoko, Nagashima, Shuichi, Yagyu, Hiroaki, Sekiya, Motohiro, Ebihara, Ken, Ishibashi, Shun
Publicado 2019

The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice

por Araki, Masaya, Nakagawa, Yoshimi, Oishi, Asayo, Han, Song-iee, Wang, Yunong, Kumagai, Kae, Ohno, Hiroshi, Mizunoe, Yuhei, Iwasaki, Hitoshi, Sekiya, Motohiro, Matsuzaka, Takashi, Shimano, Hitoshi
Publicado 2018

Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion

por Sekiya, Motohiro, Matsuda, Takaaki, Yamamoto, Yuki, Furuta, Yasuhisa, Ohyama, Mariko, Murayama, Yuki, Sugano, Yoko, Ohsaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Yatoh, Shigeru, Suzuki, Hiroaki, Shimano, Hitoshi
Publicado 2020

The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis

por Sekiya, Motohiro, Kainoh, Kenta, Sugasawa, Takehito, Yoshino, Ryunosuke, Hirokawa, Takatsugu, Tokiwa, Hiroaki, Nakano, Shogo, Nagatoishi, Satoru, Tsumoto, Kouhei, Takeuchi, Yoshinori, Miyamoto, Takafumi, Matsuzaka, Takashi, Shimano, Hitoshi
Publicado 2021

Relationships between Cognitive Function and Odor Identification, Balance Capability, and Muscle Strength in Middle-Aged Persons with and without Type 2 Diabetes

por Midorikawa, Manabu, Suzuki, Hiroaki, Suzuki, Yasuhiro, Yamauchi, Kazuyoshi, Sato, Hiroyuki, Nemoto, Kiyotaka, Sugano, Yoko, Iwasaki, Hitoshi, Sekiya, Motohiro, Yatoh, Shigeru, Yahagi, Naoya, Hada, Yasushi, Arai, Tetsuaki, Shimano, Hitoshi
Publicado 2021

A Rare Coexistence of Pheochromocytoma and Parkinson's Disease With Diagnostic Challenges

por Matsumura-Matsuda, Erika, Sekiya, Motohiro, Omoto-Inuzuka, Miyoko, Santo, Kana, Shikama, Akito, Kuba, Motoko, Sugano, Yoko, Iwasaki, Hitoshi, Yatoh, Shigeru, Sato, Taiki, Hara, Hisato, Takekoshi, Kazuhiro, Suzuki, Hiroaki, Shimano, Hitoshi
Publicado 2017

A case of early-onset diabetes with impaired insulin secretion carrying a PAX6 gene Gln135* mutation

por Sekiya, Motohiro, Yuhara, Mikiko, Murayama, Yuki, Ohyama Osawa, Mariko, Nakajima, Rikako, Ohuchi, Nami, Matsumoto, Nako, Yamazaki, Daichi, Mori, Sayuri, Matsuda, Takaaki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Suzuki, Hiroaki, Shimano, Hitoshi
Publicado 2022

Effects of Branched-Chain Amino Acids on Skeletal Muscle, Glycemic Control, and Neuropsychological Performance in Elderly Persons with Type 2 Diabetes Mellitus: An Exploratory Rand...

por Matsuda, Takaaki, Suzuki, Hiroaki, Sugano, Yoko, Suzuki, Yasuhiro, Yamanaka, Daisuke, Araki, Risa, Yahagi, Naoya, Sekiya, Motohiro, Kawakami, Yasushi, Osaki, Yoshinori, Iwasaki, Hitoshi, Hashimoto, Koichi, Takahashi, Shin-Ichiro, Hada, Yasushi, Shimano, Hitoshi
Publicado 2022

Selective peroxisome proliferator‐activated receptor‐α modulator K‐877 efficiently activates the peroxisome proliferator‐activated receptor‐α pathway and improves lipid metabolism...

por Takei, Kenta, Han, Song‐iee, Murayama, Yuki, Satoh, Aoi, Oikawa, Fusaka, Ohno, Hiroshi, Osaki, Yoshinori, Matsuzaka, Takashi, Sekiya, Motohiro, Iwasaki, Hitoshi, Yatoh, Shigeru, Yahagi, Naoya, Suzuki, Hiroaki, Yamada, Nobuhiro, Nakagawa, Yoshimi, Shimano, Hitoshi
Publicado 2017

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms

por Satoh, Aoi, Han, Song-iee, Araki, Masaya, Nakagawa, Yoshimi, Ohno, Hiroshi, Mizunoe, Yuhei, Kumagai, Kae, Murayama, Yuki, Osaki, Yoshinori, Iwasaki, Hitoshi, Sekiya, Motohiro, Konishi, Morichika, Itoh, Nobuyuki, Matsuzaka, Takashi, Sone, Hirohito, Shimano, Hitoshi
Publicado 2020

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression

por Kikuchi, Takuya, Orihara, Kana, Oikawa, Fusaka, Han, Song-iee, Kuba, Motoko, Okuda, Kanako, Satoh, Aoi, Osaki, Yoshinori, Takeuchi, Yoshinori, Aita, Yuichi, Matsuzaka, Takashi, Iwasaki, Hitoshi, Yatoh, Shigeru, Sekiya, Motohiro, Yahagi, Naoya, Suzuki, Hiroaki, Sone, Hirohito, Nakagawa, Yoshimi, Yamada, Nobuhiro, Shimano, Hitoshi
Publicado 2016

Rapid manipulation of mitochondrial morphology in a living cell with iCMM

por Miyamoto, Takafumi, Uosaki, Hideki, Mizunoe, Yuhei, Han, Song-Iee, Goto, Satoi, Yamanaka, Daisuke, Masuda, Masato, Yoneyama, Yosuke, Nakamura, Hideki, Hattori, Naoko, Takeuchi, Yoshinori, Ohno, Hiroshi, Sekiya, Motohiro, Matsuzaka, Takashi, Hakuno, Fumihiko, Takahashi, Shin-Ichiro, Yahagi, Naoya, Ito, Koichi, Shimano, Hitoshi
Publicado 2021

Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism

por Sharma, Rahul, Matsuzaka, Takashi, Kaushik, Mahesh K., Sugasawa, Takehito, Ohno, Hiroshi, Wang, Yunong, Motomura, Kaori, Shimura, Takuya, Okajima, Yuka, Mizunoe, Yuhei, Ma, Yang, Saber, Zahara M., Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Aita, Yuichi, Han, Song-iee, Takeuchi, Yoshinori, Yahagi, Naoya, Miyamoto, Takafumi, Sekiya, Motohiro, Nakagawa, Yoshimi, Shimano, Hitoshi
Publicado 2019

Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids

por Han, Song-Iee, Nakakuki, Masanori, Nakagawa, Yoshimi, Wang, Yunong, Araki, Masaya, Yamamoto, Yuta, Tokiwa, Hiroaki, Takeda, Hiroyuki, Mizunoe, Yuhei, Motomura, Kaori, Ohno, Hiroshi, Kainoh, Kenta, Murayama, Yuki, Aita, Yuichi, Takeuchi, Yoshinori, Osaki, Yoshinori, Miyamoto, Takafumi, Sekiya, Motohiro, Matsuzaka, Takashi, Yahagi, Naoya, Sone, Hirohito, Daitoku, Hiroaki, Sato, Ryuichiro, Kawano, Hiroyuki, Shimano, Hitoshi
Publicado 2023

Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity

por Saito, Kenji, Sekiya, Motohiro, Kainoh, Kenta, Yoshino, Ryunosuke, Hayashi, Akio, Han, Song-Iee, Araki, Masaya, Ohno, Hiroshi, Takeuchi, Yoshinori, Tsuyuzaki, Tomomi, Yamazaki, Daichi, Wanpei, Chen, Hada, Lisa, Watanabe, Sho, Paramita Adi Putri, Putu Indah, Murayama, Yuki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Suzuki, Hiroaki, Miyamoto, Takafumi, Matsuzaka, Takashi, Shimano, Hitoshi
Publicado 2023

A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction

por Nakajima, Rikako, Sekiya, Motohiro, Furuta, Yasuhisa, Miyamoto, Takafumi, Sato, Masashi, Fukuda, Kuniaki, Hattori, Keiichiro, Suehara, Yasuhito, Sakata-Yanagimoto, Mamiko, Chiba, Shigeru, Okajima, Yuka, Matsuzaka, Takashi, Takase, Satoru, Takanashi, Mikio, Okazaki, Hiroaki, Takashima, Yusuke, Yuhara, Mikiko, Mitani, Yuta, Matsumoto, Nako, Murayama, Yuki, Ohyama Osawa, Mariko, Ohuchi, Nami, Yamazaki, Daichi, Mori, Sayuri, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Suzuki, Hiroaki, Shimano, Hitoshi
Publicado 2022