CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance

por Li, Yu, Guaman Tipan, Pablo, Selden, Hilary J, Srinivasan, Jayashree, Hale, Laura P, Ehrlich, Lauren IR
Publicado 2023

Central tolerance is impaired in the middle‐aged thymic environment

por Lancaster, Jessica N., Keatinge‐Clay, Damaris E., Srinivasan, Jayashree, Li, Yu, Selden, Hilary J., Nam, Seohee, Richie, Ellen R., Ehrlich, Lauren I. R.
Publicado 2022

The initial age‐associated decline in early T‐cell progenitors reflects fewer pre‐thymic progenitors and altered signals in the bone marrow and thymus microenvironments

por Srinivasan, Jayashree, Vasudev, Anusha, Shasha, Carolyn, Selden, Hilary J., Perez, Encarnacion, LaFleur, Bonnie, Sinari, Shripad A., Krueger, Andreas, Richie, Ellen R., Ehrlich, Lauren I. R.
Publicado 2023