CRB3 and the FERM protein EPB41L4B regulate proliferation of mammary epithelial cells through the release of amphiregulin

por Walker, Stephanie J., Selfors, Laura M., Margolis, Ben L., Brugge, Joan S.
Publicado 2018

Evidence for a multipotent mammary progenitor with pregnancy-specific activity

por Kaanta, Alice S, Virtanen, Carl, Selfors, Laura M, Brugge, Joan S, Neel, Benjamin G
Publicado 2013

Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

por Zoeller, Jason J., Bronson, Roderick T., Selfors, Laura M., Mills, Gordon B., Brugge, Joan S.
Publicado 2017

Erratum: Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

por Zoeller, Jason J., Bronson, Roderick T., Selfors, Laura M., Mills, Gordon B., Brugge, Joan S.
Publicado 2017

Identification of cancer genes that are independent of dominant proliferation and lineage programs

por Selfors, Laura M., Stover, Daniel G., Harris, Isaac S., Brugge, Joan S., Coloff, Jonathan L.
Publicado 2017

Clinical evaluation of BCL-2/X(L) levels pre- and post- HER2-targeted therapy

por Zoeller, Jason J., Press, Michael F., Selfors, Laura M., Dering, Judy, Slamon, Dennis J., Hurvitz, Sara A., Brugge, Joan S.
Publicado 2021

Profiling Y561-Dependent and -Independent Substrates of CSF-1R in Epithelial Cells

por Knowlton, Melodie L., Selfors, Laura M., Wrobel, Carolyn N., Gu, Ting-Lei, Ballif, Bryan A., Gygi, Steven P., Polakiewicz, Roberto, Brugge, Joan S.
Publicado 2010

A protein interaction map for cell-cell adhesion regulators identifies DUSP23 as a novel phosphatase for β-catenin

por Gallegos, Lisa Leon, Ng, Mei Rosa, Sowa, Mathew E., Selfors, Laura M., White, Anne, Zervantonakis, Ioannis K., Singh, Pragya, Dhakal, Sabin, Harper, J. Wade, Brugge, Joan S.
Publicado 2016

Fibroblast–tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways

por Zervantonakis, Ioannis K., Poskus, Matthew D., Scott, Alexis L., Selfors, Laura M., Lin, Jia-Ren, Dillon, Deborah A., Pathania, Shailja, Sorger, Peter K., Mills, Gordon B., Brugge, Joan S.
Publicado 2020

Simultaneous isolation of hormone receptor–positive breast cancer organoids and fibroblasts reveals stroma-mediated resistance mechanisms

por Hogstrom, Jenny M., Cruz, Kayla A., Selfors, Laura M., Ward, Madelyn N., Mehta, Tejas S., Kanarek, Naama, Philips, Jordana, Dialani, Vandana, Wulf, Gerburg, Collins, Laura C., Patel, Jaymin M., Muranen, Taru
Publicado 2023

Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response

por Zervantonakis, Ioannis K., Iavarone, Claudia, Chen, Hsing-Yu, Selfors, Laura M., Palakurthi, Sangeetha, Liu, Joyce F., Drapkin, Ronny, Matulonis, Ursula, Leverson, Joel D., Sampath, Deepak, Mills, Gordon B., Brugge, Joan S.
Publicado 2017

Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities

por Tolopko, Andrew N, Sullivan, John P, Erickson, Sean D, Wrobel, David, Chiang, Su L, Rudnicki, Katrina, Rudnicki, Stewart, Nale, Jennifer, Selfors, Laura M, Greenhouse, Dara, Muhlich, Jeremy L, Shamu, Caroline E
Publicado 2010

Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors

por Choi, Bo-Hyun, Rawat, Vipin, Högström, Jenny, Burns, Philippa A., Conger, Kelly O., Ozgurses, Mete Emir, Patel, Jaymin M., Mehta, Tejas S., Warren, Angelica, Selfors, Laura M., Muranen, Taru, Coloff, Jonathan L.
Publicado 2022

Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages

por Rosenbluth, Jennifer M., Schackmann, Ron C. J., Gray, G. Kenneth, Selfors, Laura M., Li, Carman Man-Chung, Boedicker, Mackenzie, Kuiken, Hendrik J., Richardson, Andrea, Brock, Jane, Garber, Judy, Dillon, Deborah, Sachs, Norman, Clevers, Hans, Brugge, Joan S.
Publicado 2020

Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing

por Li, Carman Man-Chung, Shapiro, Hana, Tsiobikas, Christina, Selfors, Laura M., Chen, Huidong, Rosenbluth, Jennifer, Moore, Kaitlin, Gupta, Kushali P., Kenneth Gray, G., Oren, Yaara, Steinbaugh, Michael J., Guerriero, Jennifer L., Pinello, Luca, Regev, Aviv, Brugge, Joan S.
Publicado 2020

PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival

por Irie, Hanna Y., Shrestha, Yashaswi, Selfors, Laura M., Frye, Fabianne, Iida, Naoko, Wang, Zhigang, Zou, Lihua, Yao, Jun, Lu, Yiling, Epstein, Charles B., Natesan, Sridaran, Richardson, Andrea L., Polyak, Kornelia, Mills, Gordon B., Hahn, William C., Brugge, Joan S.
Publicado 2010

Transient commensal clonal interactions can drive tumor metastasis

por Naffar-Abu Amara, Suha, Kuiken, Hendrik J., Selfors, Laura M., Butler, Timothy, Leung, Marco L., Leung, Cheuk T., Kuhn, Elaine P., Kolarova, Teodora, Hage, Carina, Ganesh, Kripa, Panayiotou, Richard, Foster, Rosemary, Rueda, Bo R., Aktipis, Athena, Spellman, Paul, Ince, Tan A., Xiu, Joanne, Oberley, Matthew, Gatalica, Zoran, Navin, Nicholas, Mills, Gordon B., Bronson, Rodrick T., Brugge, Joan S.
Publicado 2020

Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

por Ince, Tan A., Sousa, Aurea D., Jones, Michelle A., Harrell, J. Chuck, Agoston, Elin S., Krohn, Marit, Selfors, Laura M., Liu, Wenbin, Chen, Ken, Yong, Mao, Buchwald, Peter, Wang, Bin, Hale, Katherine S., Cohick, Evan, Sergent, Petra, Witt, Abigail, Kozhekbaeva, Zhanna, Gao, Sizhen, Agoston, Agoston T., Merritt, Melissa A., Foster, Rosemary, Rueda, Bo R., Crum, Christopher P., Brugge, Joan S., Mills, Gordon B.
Publicado 2015

Glutathione supports lipid abundance in vivo

por Asantewaa, Gloria, Tuttle, Emily T., Ward, Nathan P., Kang, Yun Pyo, Kim, Yumi, Kavanagh, Madeline E., Girnius, Nomeda, Chen, Ying, Duncan, Renae, Rodriguez, Katherine, Hecht, Fabio, Zocchi, Marco, Smorodintsev-Schiller, Leonid, Scales, TashJaé Q., Taylor, Kira, Alimohammadi, Fatemeh, Sechrist, Zachary R, Agostini-Vulaj, Diana, Schafer, Xenia L., Chang, Hayley, Smith, Zachary, O’Connor, Thomas N., Whelan, Sarah, Selfors, Laura M., Crowdis, Jett, Gray, G. Kenneth, Bronson, Roderick T., Brenner, Dirk, Rufini, Alessandro, Dirksen, Robert T., Hezel, Aram F., Huber, Aaron R., Munger, Josh, Cravatt, Benjamin F., Vasiliou, Vasilis, Cole, Calvin L, DeNicola, Gina M., Harris, Isaac S.
Publicado 2023